Results 51 to 60 of about 23,008 (222)

Unlocking the Alkynyl Bromide Radical Anion With Alternating Current for Inverse Sonogashira C─H Coupling

Advanced Science, EarlyView.
An alternating current (AC)‐promoted, Pd‐catalyzed ortho‐aryl C─H alkynylation of 2,3‐diaryl acrylaldehydes is described. This synthetic scheme accommodates a broad substrate scope, delivering alkynylated stilbene derivatives with excellent arene site selectivity.
Junya Wang, Xiaozhou Wang, Pui Ying Choy, Chi‐Wai Cheung, Li‐Wen Xu, Hung Kay Lee, Gui‐Juan Cheng, Fuk Yee Kwong   +7 more
wiley   +1 more source

Synthesis of Novel Fluorescent Sensors Based on Naphthalimide Fluorophores for the Highly Selective Hg2+-Sensing

Journal of Chemistry, 2015
With an aim to develop the new sensors for optical detection of Hg2+ ions, two novel fluorometric sensors were designed and successfully prepared using 2-(3-(2-aminoethylsulfanyl)propylsulfanyl)ethanamine and one or two N-methylnaphthalimide moieties (1 ...
Yordkhuan Tachapermpon, Pornthip Piyanuch, Narupon Prapawattanapol, Kanjarat Sukrat, Kullatat Suwatpipat, Nantanit Wanichacheva   +5 more
doaj   +1 more source

Base-Promoted S_NAr Reactions of Fluoro- and Chloroarenes as a Route to N-Aryl Indoles and Carbazoles

Molecules, 2019
KOH/DMSO-promoted C-N bond formation via nucleophilic aromatic substitution (SNAr) between chloroarenes or fluoroarenes with indoles and carbazole under transition metal-free conditions affording the corresponding N-arylated indoles and carbazoles has ...
Muhammad Asif Iqbal, Hina Mehmood, Jiaying Lv, Ruimao Hua   +3 more
doaj   +1 more source

Hydrogen‐Bond Enabled Phosphite Based Intrinsic Flame‐Retardant Solid‐Solid Phase Change Materials Using Catalyst/Solvent‐Free Multi‐Component Reaction for Battery Thermal Management

Advanced Science, EarlyView.
The phosphite group endows intrinsic flame retardancy, while the P = O bond enhances intermolecular interactions to realize solid‐solid phase transition. Battery thermal management tests show the materials extend the safe working time of lithium‐ion batteries by 200%. Cone calorimeter tests indicate a 14s delay in ignition time, and reductions of 37.6%,
Changhui Liu, Guangyuan Liang, Yuanzheng Liu, Jiantang Gao, Zeyang Li, Lin Huang, Jiateng Zhao, Junbing Xiao, Xiaoxing Zhong, Jun (Joelle) Wang   +9 more
wiley   +1 more source

Modular and Stereoselective Synthesis of Cyclobutane β‐Amino Alcohols

Angewandte Chemie, EarlyView.
Late‐stage functionalization and photoisomerization of 1,2‐azaborine leads to a general strategy for the synthesis of diversely substituted cyclobutane β‐amino alcohols. The relative stereochemistry of the resulting products is unambiguously defined by the stereospecific and stereoselective nature of the photoisomerization‐hydrogenation‐oxidation ...
Xinyu Yang, Tomoya Ozaki, Bo Li, Shih‐Yuan Liu   +3 more
wiley   +2 more sources

NGHIÊN CỨU TỔNG HỢP DẪN XUẤT QUINOLINECARBOXAMIDE VÀ THỬ NGHIỆM HOẠT TÍNH SINH HỌC

Tạp chí Khoa học Đại học Cần Thơ, 2014
Trong nghiên cứu này, hai dẫn xuất quinolinecarboxamide là N-(2-(7-chloro-quinolin-4-ylamino)ethyl)acetamide (5) và N-(2-(7-chloroquinolin-4-ylamino)ethyl)benz-amide (8) đã được tổng hợp thành công từ tác chất ban đầu là 4,7-dichloroquinoline.
Trần Thị Thùy Dương, Nguyễn Hoàng Sơn, Bùi Thị Bửu Huê   +2 more
doaj  

Preparation of Indolenines via Nucleophilic Aromatic Substitution [PDF]

Organic Letters, 2019
An unusual aromatic substitution to access indolenines is described. 2-(2-Methoxyphenyl)acetonitrile derivatives are reacted with various alkyl and aryl Li reagents to furnish the corresponding indolenine products, constituents of natural products, and cyanine dyes such as indocyanine green.
Huber, Florian, Roesslein, Joel, Gademann, Karl   +2 more
openaire   +4 more sources

Deep Learning‐Driven Discovery and Engineering of an Efficient PETase for Depolymerization and Detoxification of PET Microplastics Under Physiological Conditions

Advanced Science, EarlyView.
A deep learning–driven pipeline mining 246 million protein sequences uncovers AhPETase, an evolutionarily distinct PET hydrolase. Engineered variant AhPETaseM1 degrades post‐consumer PET microplastics under physiological conditions and reverses microplasticinduced cytotoxicity in human lung and colon cells, establishing enzymatic microplastic ...
Yuxuan Wang, Shijie He, Yuheng Chang, Sheng Mao, Jianan Canal Li, Binbin Chen, Hongxun Gao, Mingchun Xu, Chenxu Liu, Yajie Wang   +9 more
wiley   +1 more source

Aromatic Pummerer‐Promoted Stereospecific Cross‐Coupling of Thiazoles With Boronic Esters

Angewandte Chemie, EarlyView.
A lithiation–borylation–aromatic Pummerer (LiBAP) strategy enables stereospecific, C5‐selective C(sp2)–C(sp3) cross‐coupling of thiazoles with boronic esters. By using exocyclic sulfoxide activation to overcome the low nucleophilicity that frustrates SEAr‐type coupling, the method delivers enantioenriched alkylated thiazoles bearing a versatile C2 ...
Mark John P. Mandigma, Julien Lefranc, Louise Eagling, Jasper L. Tyler, Varinder K. Aggarwal   +4 more
wiley   +2 more sources

Syntheses of fluorooxindole and 2-fluoro-2-arylacetic acid derivatives from diethyl 2-fluoromalonate ester

Beilstein Journal of Organic Chemistry, 2014
Diethyl 2-fluoromalonate ester is utilised as a building block for the synthesis of 2-fluoro-2-arylacetic acid and fluorooxindole derivatives by a strategy involving nucleophilic aromatic substitution reactions with ortho-fluoronitrobenzene substrates ...
Antal Harsanyi, Graham Sandford, Dmitri S. Yufit, Judith A.K. Howard   +3 more
doaj   +1 more source