Identification and characterization of codon usage pattern and influencing factors in HFRS-causing hantaviruses [PDF]
Frontiers in Immunology, 2023 Hemorrhagic fever with renal syndrome (HFRS) is an acute viral zoonosis carried and transmitted by infected rodents through urine, droppings, or saliva.
Fatima Noor +7 more
doaj +2 more sources
Comprehensive computational analysis reveals YXXΦ[I/L/M/F/V] motif and YXXΦ-like tetrapeptides across HFRS causing Hantaviruses and their association with viral pathogenesis and host immune regulation [PDF]
Frontiers in Immunology, 2022 Hemorrhagic fever with renal syndrome (HFRS) is an acute zoonotic disease transmitted through aerosolized excrement of rodents. The etiology of HFRS is complex due to the involvement of viral factors and host immune and genetic factors. The viral species
Fatima Noor +5 more
doaj +2 more sources
Serological Evidence of Hantavirus in Bats from the Brazilian Atlantic Forest: An Investigation of Seroreactivity and Cross-Reactivity of Neotropical Bat Samples Using Nucleoproteins of Rodent- and Bat-Borne Hantaviruses [PDF]
VirusesHantaviruses are zoonotic pathogens associated with severe human diseases such as hemorrhagic fever with renal syndrome and hantavirus pulmonary syndrome.
Caroline Lacorte Rangel +13 more
doaj +2 more sources
Revealing long-range heterogeneous organization of nucleoproteins with 6mA footprinting by ipdTrimming [PDF]
Genome BiologyEnabled by long-read sequencing technologies, particularly Single Molecule, Real-Time sequencing, N6-methyladenine (6mA) footprinting is a transformative methodology for revealing the heterogenous and dynamic distribution of nucleosomes and other DNA ...
Wentao Yang +5 more
doaj +2 more sources
Nucleoproteins of Negative Strand RNA Viruses; RNA Binding, Oligomerisation and Binding to Polymerase Co-Factor [PDF]
Viruses, 2010 Commentary on Tawar, R.G.; Duquerroy, S.; Vonrhein, C.; Varela, P.F.; Damier-Piolle, L.; Castagné, N.; MacLellan, K.; Bedouelle, H.; Bricogne, G.; Bhella, D.; Eléouët, J.-F.; Rey, F.A. Crystal structure of a nucleocapsid-like nucleoprotein-RNA complex of
Thibaut Crépin, Rob W. H. Ruigrok
doaj +2 more sources
Rio Mamore Hantavirus Endemicity, Peruvian Amazon, 2020 [PDF]
Emerging Infectious DiseasesTo explore hantavirus infection patterns in Latin America, we conducted molecular and serologic hantavirus investigations among 3,400 febrile patients from Peru during 2020–2021.
Marta Piche-Ovares +10 more
doaj +2 more sources
Insights into Paramyxovirus Nucleocapsids from Diverse Assemblies
Viruses, 2021 All paramyxoviruses, which include the mumps virus, measles virus, Nipah virus, Newcastle disease virus, and Sendai virus, have non-segmented single-stranded negative-sense RNA genomes.
Tianhao Li, Qing-Tao Shen
doaj +1 more source
Epistatically interacting substitutions are enriched during adaptive protein evolution. [PDF]
PLoS Genetics, 2014 Most experimental studies of epistasis in evolution have focused on adaptive changes-but adaptation accounts for only a portion of total evolutionary change. Are the patterns of epistasis during adaptation representative of evolution more broadly?
Lizhi Ian Gong, Jesse D Bloom
doaj +1 more source
Nipah shell disorder, modes of infection, and virulence [PDF]
, 2020 The Nipah Virus (NiV) was first isolated during a 1998–9 outbreak in Malaysia. The outbreak initially infected farm pigs and then moved to humans from pigs with a case-fatality rate (CFR) of about 40%.
Dunker, A. Keith +3 more
core +1 more source
Nucleoprotein-based nanoscale assembly [PDF]
Proceedings of the National Academy of Sciences, 1997 A system for addressing in the construction of macromolecular assemblies can be based on the biospecificity of DNA (cytosine-5) methyltransferases and the capacity of these enzymes to form abortive covalent complexes at targeted 5-fluorocytosine residues in DNA.
S S, Smith +5 more
openaire +2 more sources