Identification and characterization of codon usage pattern and influencing factors in HFRS-causing hantaviruses [PDF]
Hemorrhagic fever with renal syndrome (HFRS) is an acute viral zoonosis carried and transmitted by infected rodents through urine, droppings, or saliva.
Fatima Noor +7 more
doaj +2 more sources
Serological Evidence of Hantavirus in Bats from the Brazilian Atlantic Forest: An Investigation of Seroreactivity and Cross-Reactivity of Neotropical Bat Samples Using Nucleoproteins of Rodent- and Bat-Borne Hantaviruses [PDF]
Hantaviruses are zoonotic pathogens associated with severe human diseases such as hemorrhagic fever with renal syndrome and hantavirus pulmonary syndrome.
Caroline Lacorte Rangel +13 more
doaj +2 more sources
Revealing long-range heterogeneous organization of nucleoproteins with 6mA footprinting by ipdTrimming [PDF]
Enabled by long-read sequencing technologies, particularly Single Molecule, Real-Time sequencing, N6-methyladenine (6mA) footprinting is a transformative methodology for revealing the heterogenous and dynamic distribution of nucleosomes and other DNA ...
Wentao Yang +5 more
doaj +2 more sources
ZNRD2 Mediated Nucleoprotein Aggregation Impairs Respiratory Syncytial Virus Replication [PDF]
Nucleoproteins (N) of negative‐sense RNA viruses exhibit an inherent tendency to oligomerize, forming a ribonucleoprotein complex that protects the viral genome.
Haiwu Zhou +8 more
doaj +2 more sources
Rio Mamore Hantavirus Endemicity, Peruvian Amazon, 2020 [PDF]
To explore hantavirus infection patterns in Latin America, we conducted molecular and serologic hantavirus investigations among 3,400 febrile patients from Peru during 2020–2021.
Marta Piche-Ovares +10 more
doaj +2 more sources
Hemorrhagic fever with renal syndrome (HFRS) is an acute zoonotic disease transmitted through aerosolized excrement of rodents. The etiology of HFRS is complex due to the involvement of viral factors and host immune and genetic factors. The viral species
Fatima Noor +5 more
doaj +1 more source
Insights into Paramyxovirus Nucleocapsids from Diverse Assemblies
All paramyxoviruses, which include the mumps virus, measles virus, Nipah virus, Newcastle disease virus, and Sendai virus, have non-segmented single-stranded negative-sense RNA genomes.
Tianhao Li, Qing-Tao Shen
doaj +1 more source
Epistatically interacting substitutions are enriched during adaptive protein evolution. [PDF]
Most experimental studies of epistasis in evolution have focused on adaptive changes-but adaptation accounts for only a portion of total evolutionary change. Are the patterns of epistasis during adaptation representative of evolution more broadly?
Lizhi Ian Gong, Jesse D Bloom
doaj +1 more source
Nucleoprotein-based nanoscale assembly [PDF]
A system for addressing in the construction of macromolecular assemblies can be based on the biospecificity of DNA (cytosine-5) methyltransferases and the capacity of these enzymes to form abortive covalent complexes at targeted 5-fluorocytosine residues in DNA.
S S, Smith +5 more
openaire +2 more sources
Clathrin-Mediated Endocytosis Delivers Proteolytically Active Phytaspases Into Plant Cells
Phytaspases belong to the family of plant subtilisin-like proteases and are distinct from other family members, as they have strict and rarely occurring aspartate cleavage specificity and unusual localization dynamics.
Svetlana V. Trusova +6 more
doaj +1 more source

