Results 1 to 10 of about 6,868 (144)

Identification and characterization of codon usage pattern and influencing factors in HFRS-causing hantaviruses [PDF]

open access: yesFrontiers in Immunology, 2023
Hemorrhagic fever with renal syndrome (HFRS) is an acute viral zoonosis carried and transmitted by infected rodents through urine, droppings, or saliva.
Fatima Noor   +7 more
doaj   +2 more sources

Serological Evidence of Hantavirus in Bats from the Brazilian Atlantic Forest: An Investigation of Seroreactivity and Cross-Reactivity of Neotropical Bat Samples Using Nucleoproteins of Rodent- and Bat-Borne Hantaviruses [PDF]

open access: yesViruses
Hantaviruses are zoonotic pathogens associated with severe human diseases such as hemorrhagic fever with renal syndrome and hantavirus pulmonary syndrome.
Caroline Lacorte Rangel   +13 more
doaj   +2 more sources

Revealing long-range heterogeneous organization of nucleoproteins with 6mA footprinting by ipdTrimming [PDF]

open access: yesGenome Biology
Enabled by long-read sequencing technologies, particularly Single Molecule, Real-Time sequencing, N6-methyladenine (6mA) footprinting is a transformative methodology for revealing the heterogenous and dynamic distribution of nucleosomes and other DNA ...
Wentao Yang   +5 more
doaj   +2 more sources

ZNRD2 Mediated Nucleoprotein Aggregation Impairs Respiratory Syncytial Virus Replication [PDF]

open access: yesAdvanced Science
Nucleoproteins (N) of negative‐sense RNA viruses exhibit an inherent tendency to oligomerize, forming a ribonucleoprotein complex that protects the viral genome.
Haiwu Zhou   +8 more
doaj   +2 more sources

Rio Mamore Hantavirus Endemicity, Peruvian Amazon, 2020 [PDF]

open access: yesEmerging Infectious Diseases
To explore hantavirus infection patterns in Latin America, we conducted molecular and serologic hantavirus investigations among 3,400 febrile patients from Peru during 2020–2021.
Marta Piche-Ovares   +10 more
doaj   +2 more sources

Comprehensive computational analysis reveals YXXΦ[I/L/M/F/V] motif and YXXΦ-like tetrapeptides across HFRS causing Hantaviruses and their association with viral pathogenesis and host immune regulation

open access: yesFrontiers in Immunology, 2022
Hemorrhagic fever with renal syndrome (HFRS) is an acute zoonotic disease transmitted through aerosolized excrement of rodents. The etiology of HFRS is complex due to the involvement of viral factors and host immune and genetic factors. The viral species
Fatima Noor   +5 more
doaj   +1 more source

Insights into Paramyxovirus Nucleocapsids from Diverse Assemblies

open access: yesViruses, 2021
All paramyxoviruses, which include the mumps virus, measles virus, Nipah virus, Newcastle disease virus, and Sendai virus, have non-segmented single-stranded negative-sense RNA genomes.
Tianhao Li, Qing-Tao Shen
doaj   +1 more source

Epistatically interacting substitutions are enriched during adaptive protein evolution. [PDF]

open access: yesPLoS Genetics, 2014
Most experimental studies of epistasis in evolution have focused on adaptive changes-but adaptation accounts for only a portion of total evolutionary change. Are the patterns of epistasis during adaptation representative of evolution more broadly?
Lizhi Ian Gong, Jesse D Bloom
doaj   +1 more source

Nucleoprotein-based nanoscale assembly [PDF]

open access: yesProceedings of the National Academy of Sciences, 1997
A system for addressing in the construction of macromolecular assemblies can be based on the biospecificity of DNA (cytosine-5) methyltransferases and the capacity of these enzymes to form abortive covalent complexes at targeted 5-fluorocytosine residues in DNA.
S S, Smith   +5 more
openaire   +2 more sources

Clathrin-Mediated Endocytosis Delivers Proteolytically Active Phytaspases Into Plant Cells

open access: yesFrontiers in Plant Science, 2019
Phytaspases belong to the family of plant subtilisin-like proteases and are distinct from other family members, as they have strict and rarely occurring aspartate cleavage specificity and unusual localization dynamics.
Svetlana V. Trusova   +6 more
doaj   +1 more source

Home - About - Disclaimer - Privacy