Results 161 to 170 of about 235,474 (365)
Metabolisms of Nucleosides in Bacteria
Agricultural and Biological Chemistry, 1965 Pyrimidine nucleoside phosphorylases obtained from Er. carotovora and Cor. sepedonicum were purified by means of ammonium sulfate fractionation and DEAE-cellulose column chromatography. Some properties of these enzyme were also studied. The enzyme from Cor.
Takamitsu Yorifuji +3 more
openaire +6 more sources
Role of RNA modifications in carcinogenesis and carcinogen damage response
Molecular Carcinogenesis, Volume 62, Issue 1, Page 24-37, January 2023., 2023 Abstract The field of epitranscriptomics encompasses the study of post‐transcriptional RNA modifications and their regulatory enzymes. Among the numerous RNA modifications, N6‐methyladenosine (m6A) has been identified as the most common internal modification of messenger RNA (mRNA).
Michelle Verghese +2 more
wiley +1 more source
Beilstein Journal of Organic Chemistry, 2017 The 5’-alkynylation of uridine-derived aldehydes is described. The addition of alkynyl Grignard reagents on the carbonyl group is significantly influenced by the 2’,3’-di-O-protecting groups (R1): O-alkyl groups led to modest diastereoselectivities (65 ...
Raja Ben Othman +4 more
doaj +1 more source
Toxicity-related antiretroviral drug treatment modifications in individuals starting therapy: a cohort analysis of time patterns, sex, and other risk factors. [PDF]
, 2013 BackgroundModifications to combination antiretroviral drug therapy (CART) regimens can occur for a number of reasons, including adverse drug effects.
Begovac, Josip +4 more
core +1 more source
Isolation and Separation of the Pyrimidine Nucleosides of Yeast Ribosenucleic Acid [PDF]
, 1948 R. J. C. Harris, J. F. Thomas
openalex +1 more source
ChemBioChem, EarlyView.The findings of thermal denaturation experiments indicate that duplexes containing thymine analogues with 1,2‐ethylenediamine side chains show stabilizing effects with six metal ions (e.g., Cu(II), Ni(II), Zn(II), Co(II), Cd(II)). The 1,2‐diamine side chain demonstrated to be useful as a new metal‐ion binding site. Thymidine analogue with a 1,2‐diamino
Takahiro Atsugi +3 more
wiley +1 more source
AASLD practice guidance on drug, herbal, and dietary supplement–induced liver injury
, 2022 Hepatology, EarlyView.
Robert J. Fontana +6 more
wiley +1 more source
5'-nucleotidases, nucleosides and their distribution in the brain: pathological and therapeutic implications [PDF]
, 2013 Elements of the nucleoside system (nucleoside levels, 5'-nucleotidases (5'NTs) and other nucleoside metabolic enzymes, nucleoside transporters and nucleoside receptors) are unevenly distributed in the brain, suggesting that nucleosides have region ...
Dobolyi, Árpád +3 more
core
ChemBioChem, EarlyView.In the nascent processes of the beginnings and evolution of life, nucleobases and especially purines, ribonucleos(t)ides and primitive RNAs have been continuously modified. A RNA‐peptide world and key metabolic pathways probably have emerged from the corresponding chemical modifications resulting from adenine deamination, purine alkylation and ...
Jean‐Luc Décout +1 more
wiley +1 more source