Results 201 to 210 of about 235,474 (365)

Chiral Materials from Biomass: 3‐deoxy‐α‐D‐ribono‐1,4‐lactone and 3‐deoxy‐α‐D‐arabino‐1,4‐lactone via the Bromination of Cyrene

open access: yesEuropean Journal of Organic Chemistry, EarlyView.
The biomass pyrolysis product levoglucosenone enables the preparation of the feeding modulator 3‐deoxy‐d‐arabino‐1,4‐lactone and the diastereomer 3‐deoxy‐d‐ribono‐1,4‐lactone. The key steps involve a diastereoselective bromination using an enamine bromination‐hydrolysis strategy on the bicyclic ring‐system followed by selective nucleophilic ...
Johannes Puschnig   +2 more
wiley   +1 more source

DEGRADATION OF SUBSTITUTED PYRIMIDINE NUCLEOSIDES BY ESCHERICHIA COLI AND BACILLUS SUBTILIS

open access: hybrid, 1954
Irving J. Slotnick   +2 more
openalex   +1 more source

Contactless Conductivity Detection for Capillary Electrophoresis—Developments From 2020 to 2024

open access: yesELECTROPHORESIS, EarlyView.
ABSTRACT The review covering the development of capillary electrophoresis with capacitively coupled contactless conductivity detection from 2020 to 2024 is the latest in a series going back to 2004. The article considers applications employing conventional capillaries and planar lab‐on‐chip devices as well as fundamental and technical developments of ...
Peter C. Hauser, Pavel Kubáň
wiley   +1 more source

A Comprehensive Evaluation of Analytical Method Parameters Critical to the Reliable Assessment of Therapeutic mRNA Integrity by Capillary Gel Electrophoresis

open access: yesELECTROPHORESIS, EarlyView.
ABSTRACT In recent years, messenger ribonucleic acid (mRNA)‐lipid nanoparticle (LNP) biotherapeutics have demonstrated significant promise in disease treatment and prevention given their rapidly modifiable production processes and considerable capacity to adapt to complex or low‐yielding proteins of interest.
Jessica P. Tran   +7 more
wiley   +1 more source

Epigenotoxicity: Decoding the epigenetic imprints of genotoxic agents and their implications for regulatory genetic toxicology

open access: yesEnvironmental and Molecular Mutagenesis, EarlyView.
Abstract Regulatory genetic toxicology focuses on DNA damage and subsequent gene mutations. However, genotoxic agents can also affect epigenetic marks, and incorporation of epigenetic data into the regulatory framework may thus enhance the accuracy of risk assessment.
Roger Godschalk   +4 more
wiley   +1 more source

A review of Mpox: Biological characteristics, epidemiology, clinical features, diagnosis, treatment, and prevention strategies

open access: yesExploration, EarlyView.
The monkeypox virus (MPXV) has spread to many countries and caused thousands of infections all over the world. This review comprehensively introduces the biology, epidemiological characteristics of MPXV, and clinical manifestations of Mpox. The approaches for diagnosis, treatment, and prevention are also introduced, aiming to improve the general ...
Lin Jiang   +15 more
wiley   +1 more source

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