Results 301 to 310 of about 339,632 (390)

First‐in‐class inhibitors of SbnA reduce siderophore production in Staphylococcus aureus

The FEBS Journal, EarlyView.
The production of the iron‐chelating compound staphyloferrin B by the most invasive S. aureus strains is crucial for colonization, virulence, and survival in the host. Staphyloferrin B biosynthesis is carried out by eight enzymes, the Sbn system, that offer an appealing source of potential targets for the development of antimicrobials.
Sarah Hijazi, Monica Cozzi, Somayeh Asgharpour, Omar De Bei, Serena Faggiano, Francesco Marchesani, Luca Ronda, Marialaura Marchetti, Eleonora Gianquinto, Mariacristina Failla, Gauthier Trèves, Loretta Lazzarato, Francesca Spyrakis, Barbara Campanini, Emanuela Frangipani, Stefano Bettati   +15 more
wiley   +1 more source

3'-<i>O</i>-β-Glucosylation of nucleoside analogues using a promiscuous bacterial glycosyltransferase. [PDF]

RSC Chem Biol
Dolan JP, Keenan T, Cheallaigh AN, Fascione MA, Miller GJ.   +4 more
europepmc   +1 more source

The association between HIV drug resistance testing, viral suppression and mortality in Ontario: a retrospective cohort study

HIV Medicine, EarlyView.
Abstract Background Drug resistance compromises the effectiveness of antiretroviral therapy (ART). Resistance testing prior to initiating therapy is recommended in guidelines in many high‐income countries, and it has been shown to improve outcomes after first‐line ART regimen failure. There is limited evidence on its role in treatment‐naïve individuals.
Lawrence Mbuagbaw, Carmen H. Logie, Lehana Thabane, Fiona Smaill, Marek Smieja, Ann N. Burchell, Beth Rachlis, Jean Eric Tarride, Abigail E. Kroch, Tony Mazzulli, Elizabeth Alvarez, Francis Nguyen, Richard Perez, Cristian Garcia, Jessyca Matos Silva, Hsien Seow   +15 more
wiley   +1 more source

Transphosphorylation from Nucleoside Di- and Triphosphates by Apatite Crystals

, 1962
Stephen M. Krane, Melvin J. Glimcher
openalex   +1 more source

Cardiovascular risk knowledge stratified by predicted cardiovascular risk level among people living with HIV attending a tertiary HIV care centre in Gaborone, Botswana: A cross‐sectional study

HIV Medicine, EarlyView.
Abstract Objectives While people living with HIV are at an increased risk of cardiovascular disease (CVD), the level of awareness of CVD risk in this population is not well documented. This study aimed to assess the association between CVD risk factor knowledge and estimated CVD risk among people living with HIV.
Bernard Morapedi, Onkabetse Julia Molefe‐Baikai, Onkarabile Hiri, Kago Kebotsamang, Thato Moshomo, Mosepele Mosepele   +5 more
wiley   +1 more source

The Role of Uridine in Health and Disease. [PDF]

J Inflamm Res
Song C, Liu ZJ, Xu B, Zou R, Hu W.
europepmc   +1 more source

Purification and Properties of a Nucleoside Triphosphate Pyrophosphohydrolase from Red Cells of the Rabbit

, 1969
C.J. Chern, Alexander MacDonald, Allan J. Morris   +2 more
openalex   +1 more source

Leukocyte count and new‐onset diabetes mellitus in people with HIV: A longitudinal study

HIV Medicine, EarlyView.
Abstract Objectives The risk of diabetes mellitus (DM) is increased in people with HIV. Chronic inflammation contributes to DM risk. High leukocytes are associated with DM in the general population, but in people with HIV, evidence of a leukocyte–DM association is limited. Methods We included participants of the Swiss HIV Cohort Study with new‐onset DM
Sophia C. Meyer, Zoe Klein, Isabella C. Schoepf, Christian W. Thorball, Marco Labarile, Neeltje A. Kootstra, Peter Reiss, Lene Ryom, Dominique L. Braun, Maria C. Thurnheer, Catia Marzolini, Christian R. Kahlert, Enos Bernasconi, Matthias Cavassini, Annalisa Marinosci, Jacques Fellay, Huldrych F. Günthard, Roger D. Kouyos, Bruno Ledergerber, Philip E. Tarr, the Swiss HIV Cohort Study, I Abela, K Aebi‐Popp, A Anagnostopoulos, M Battegay, E Bernasconi, DL Braun, HC Bucher, A Calmy, M Cavassini, A Ciuffi, G Dollenmaier, M Egger, L Elzi, J Fehr, J Fellay, H Furrer, CA Fux, HF Günthard, A Hachfeld, D Haerry, B Hasse, HH Hirsch, M Hoffmann, I Hösli, M Huber, D Jackson‐Perry, patient representatives, CR Kahlert, O Keiser, T Klimkait, RD Kouyos, H Kovari, K Kusejko, N Labhardt, K Leuzinger, B Martinez de Tejada, C Marzolini, KJ Metzner, N Müller, J Nemeth, D Nicca, J Notter, P Paioni, G Pantaleo, M Perreau, A Rauch, L Salazar‐Vizcaya, P Schmid, R Speck, M Stöckle, P Tarr, A Trkola, G Wandeler, M Weisser, S. Yerly   +75 more
wiley   +1 more source

Pharmacokinetics and Metabolism of Broad-Spectrum Antivirals Remdesivir and Obeldesivir with a Consideration to Metabolite GS-441524: Same, Similar, or Different? [PDF]

Viruses
Babusis D, Kim C, Yang J, Zhao X, Geng G, Ip C, Kozon N, Le H, Leung J, Pitts J, Siegel DS, Kalla R, Murray B, Bilello JP, Bannister R, Mackman RL, Subramanian R.   +16 more
europepmc   +1 more source

On the Benzylation of Nucleosides. II. A Novel Synthesis of 2'-O-Benzyluridine

, 1968
Kiyomi Kikugawa, Fumiko Sato, Takashi Tsuruo, Nobumasa Imura, Tyunosin Ukita   +4 more
openalex   +2 more sources