Results 61 to 70 of about 235,325 (216)

State-dependent fragmentation of protonated uracil and uridine [PDF]

, 2019
Tandem mass spectroscopy ($\textrm{MS}^2$) combined with single photon excitation in the VUV range (photon energy 4.5-9 eV) was performed on protonated uracil ($\textrm{UraH}^{+}$) and uridine ($\textrm{UrdH}^{+}$). The precursor ions with $m/z\;113$ and $m/z\;245$ respectively were produced by an Electrospray Ionization source (ESI) and accumulated ...
arxiv   +1 more source

Inhibition of adenovirus serotype 14 infection by octadecyloxyethyl esters of (S)-[(3-hydroxy-2-phosphonomethoxy)propyl]- nucleosides in vitro. [PDF]

, 2018
On September 22, 2008, a physician on Prince of Wales Island, Alaska, notified the Alaska Department of Health and Social Services (ADHSS) of an unusually high number of adult patients with recently diagnosed pneumonia (n = 10), including three persons ...
Barnard, Dale L, Beadle, James R, Hostetler, Karl Y, Kumaki, Yohichi, Mclean, Tyler Z, Roth, Jason P, Smee, Donald F, Valiaeva, Nadejda, Woolcott, John D   +8 more
core  

Utilization of a deoxynucleoside diphosphate substrate by HIV reverse transcriptase [PDF]

, 2008
Background: Deoxynucleoside triphosphates (dNTPs) are the normal substrates for DNA sysnthesis is catalyzed by polymerases such as HIV-1 reverse transcriptase (RT).
A Bevington, A Mas, AJ Smith, B Selmi, BA Barshop, BA Mulder, BR Bochner, C Cruchaga, C Isnard Bagnis, CK Tan, D Arion, EF Pettersen, G Pontarin, G Pontarin, G Yang, G Yang, GJ Kemp, H Huang, H Ling, H Pelletier, H Pelletier, HK Schachman, IA Nazarenko, K Bebenek, KL White, Kornberg, Linqi Zhang, M Rigourd, MC Franklin, Michael A. Parniak, MJ Bessman, MK Kukhanova, N Sluis-Cremer, PJ Rothwell, PL Boyer, PM Burgers, PM Burgers, PR Meyer, PR Meyer, PR Meyer, PR Meyer, PR Meyer, RS Fletcher, S Dharmasena, Scott J. Garforth, SJ Garforth, SV Doronin, SV Doronin, TA Kunkel, TA Rozovskaya, TA Steitz, UM Parikh, Vinayaka R. Prasad, Z Gu   +53 more
core   +3 more sources

Metabolic and functional consequences of cytosolic 5′-nucleotidase-IA overexpression in neonatal rat cardiomyocytes [PDF]

, 2003
Adenosine exerts a spectrum of energy-preserving actions on the heart negative chronotropic effects. The pathways leading to adenosine formation have remained controversial.
Curto, Maria de Los Angeles, Freeman, Nicola V. E., Newby, Andrew C., Sala-Newby, Graciela B.   +3 more
core   +1 more source

C5-Azobenzene-substituted 2'-Deoxyuridine-containing Oligodeoxynucleotides for Photo-Switching Hybridization

Molecules, 2014
A new photoisomeric nucleoside dUAz bearing an azobenzene group at the C5-position of 2'-deoxyuridine was designed and synthesized. Photoisomerization of dUAz in oligodeoxynucleotides can be achieved rapidly and selectively with 365 nm (forward) and 450
Shohei Mori, Kunihiko Morihiro, Satoshi Obika   +2 more
doaj   +1 more source

Dietary Supplementation With Bacillus subtilis Direct-Fed Microbials Alters Chicken Intestinal Metabolite Levels

Frontiers in Veterinary Science, 2020
Direct-fed microbials (DFMs) are dietary supplements containing live microorganisms which confer a performance and health benefit to the host, but the mechanisms are unclear.
Inkyung Park, Noah P. Zimmerman, Alexandra H. Smith, Thomas G. Rehberger, Erik. P. Lillehoj, Hyun S. Lillehoj   +5 more
doaj   +1 more source

Expanding a fluorescent RNA alphabet: synthesis, photophysics and utility of isothiazole-derived purine nucleoside surrogates. [PDF]

, 2017
A series of emissive ribonucleoside purine mimics, all comprised of an isothiazolo[4,3-d]pyrimidine core, was prepared using a divergent pathway involving a key Thorpe-Ziegler cyclization.
Fin, Andrea, Rovira, Alexander R, Tor, Yitzhak   +2 more
core   +1 more source

Silica Monolithic Capillary Columns for Hilic Separations

Hungarian Journal of Industry and Chemistry, 2018
The monolithic capillary columns (0.1 mm x 150 mm) prepared by the acidic hydrolysis of tetramethoxysilane (TMOS) in the presence of polyethylene glycol (PEG) and urea were modified by zwitterionic stationary phases and evaluated under HILIC separation ...
Moravcová Dana, Planeta Josef
doaj   +1 more source

Purine nucleosides replace cAMP in allosteric regulation of PKA in trypanosomatid pathogens

eLife
Cyclic nucleotide binding domains (CNB) confer allosteric regulation by cAMP or cGMP to many signaling proteins, including PKA and PKG. PKA of phylogenetically distant Trypanosoma is the first exception as it is cyclic nucleotide-independent and ...
Veronica Teresa Ober, George Boniface Githure, Yuri Volpato Santos, Sidney Becker, Gabriel Moya Munoz, Jérôme Basquin, Frank Schwede, Esben Lorentzen, Michael Boshart   +8 more
doaj   +1 more source

Transport in hybrid electronic devices based on a modified DNA nucleoside (deoxyguanosine) [PDF]

arXiv, 2000
We report on a new class of hybrid electronic devices based on a DNA nucleoside (deoxyguanosine lipophilic derivative) whose assembled polymeric ribbons interconnect a submicron metallic gate. The device exhibits large conductivity at room temperature, rectifying behaviour and strong current-voltage hysteresis.
arxiv