Results 141 to 150 of about 2,664 (174)
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Adenosine Deaminase and Purine Nucleoside Phosphorylase Activities during Culturing of Fibrolasts
1980Fibroblast cultures can be used as a valuable model for the study of inborn errors and as an important diagnostic tool, e.g. amniotic fluid derived fibroblasts in prenatal diagnosis (1–3). In order to develop reliable enzyme assays of fibroblasts the effect of cell culture conditions on enzyme activities should be known.
M P, Uitendaal +4 more
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[71] Cytosine nucleoside deaminase from Escherichia coli
1955Publisher Summary This chapter discusses the determination of cytosine nucleoside deaminase from Escherichia coli (E. coli) . Spectrophotometric methods are used in following the activity of this enzyme, since the deamination of the cytosine compounds is accompanied b y a decrease in absorption of 55 % at 282 mμ.
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Leukemia Research, 1982
Three enzymes concerned in purine degradation, 5'nucleotidase (5'NT), adenosine deaminase (ADA) and purine nucleoside phosphorylase (PNP) have been measured biochemically in the bone marrow or peripheral blood blasts from 75 patients with acute leukaemia, from 18 patients with blast crisis of chronic granulocytic leukaemia and in the bone marrow and ...
SYLWESTROWICZ TA +6 more
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Three enzymes concerned in purine degradation, 5'nucleotidase (5'NT), adenosine deaminase (ADA) and purine nucleoside phosphorylase (PNP) have been measured biochemically in the bone marrow or peripheral blood blasts from 75 patients with acute leukaemia, from 18 patients with blast crisis of chronic granulocytic leukaemia and in the bone marrow and ...
SYLWESTROWICZ TA +6 more
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Synthesis, 2005
Adenosine deaminase (ADA) and adenylic acid deaminase (AMPDA) are enzymes that catalyze the hydrolytic deamination of various purine nucleosides. In light of recent reports, ADA and AMPDA may be considered as valuable biocatalysts in nucleoside chemistry.
E. Santaniello +2 more
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Adenosine deaminase (ADA) and adenylic acid deaminase (AMPDA) are enzymes that catalyze the hydrolytic deamination of various purine nucleosides. In light of recent reports, ADA and AMPDA may be considered as valuable biocatalysts in nucleoside chemistry.
E. Santaniello +2 more
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Biochemical Medicine, 1978
Abstract Previous studies on the urine composition of an adenosine deaminase deficient child have been extended. New analytical procedures have been developed for determination of adenine, deoxyadenosine and adenosine in urine. Of these compounds, deoxyadenosine was the major urinary component.
G C, Mills +3 more
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Abstract Previous studies on the urine composition of an adenosine deaminase deficient child have been extended. New analytical procedures have been developed for determination of adenine, deoxyadenosine and adenosine in urine. Of these compounds, deoxyadenosine was the major urinary component.
G C, Mills +3 more
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Nucleoside Deaminases for Cytidine and Adenosine: Comparison with Deaminases Acting on RNA
2014This chapter reviews the structure of Escherichia coli cytidine deaminase and implications for evolutionary relationships between members of the cytidine deaminase superfamily. It then summarizes details of the E. coli cytidine deaminase (ECCDA) reaction mechanism, with particular reference to the role of conserved residues and aspects of substrate ...
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European Journal of Organic Chemistry, 2004
AbstractThe enzymes adenosine deaminase (ADA) and adenylate deaminase (AMPDA) are able to catalyze the hydrolytic dechlorination of 6‐chloropurine riboside and the corresponding 2′,3′‐O‐isopropylidene derivative, but show no activity towards the 3,4‐O‐isopropylidene‐1‐methylriboside of 6‐chloropurine and adenine. (© Wiley‐VCH Verlag GmbH & Co. KGaA,
P.Ciuffreda +3 more
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AbstractThe enzymes adenosine deaminase (ADA) and adenylate deaminase (AMPDA) are able to catalyze the hydrolytic dechlorination of 6‐chloropurine riboside and the corresponding 2′,3′‐O‐isopropylidene derivative, but show no activity towards the 3,4‐O‐isopropylidene‐1‐methylriboside of 6‐chloropurine and adenine. (© Wiley‐VCH Verlag GmbH & Co. KGaA,
P.Ciuffreda +3 more
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Adenosine Deaminase and Purine Nucleoside Phosphorylase in Acute and Chronic Lymphatic Leukemia
1980Significant progress in the classification of leukemia has been achieved by the introduction of methods which make detailled characterisation of cell membrane antigens or receptors possible (1). These methods have proved to be of considerable clinical relevance as tools for precise classification of the underlying leukemic process, thus providing more ...
H, Ludwig +3 more
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1984
The present study was undertaken to study 3 selected purine pathway enzymes in infectious mononucleosis (IM). The enzymes concerned are adenosine deaminase (ADA), purine nucleoside phosphorylase (PNP) and 5′-nucleotidase (5′-N). The enzymes were selected since the absence of these enzymes have been associated with clinically defective lymphoid function
J, Mejer +4 more
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The present study was undertaken to study 3 selected purine pathway enzymes in infectious mononucleosis (IM). The enzymes concerned are adenosine deaminase (ADA), purine nucleoside phosphorylase (PNP) and 5′-nucleotidase (5′-N). The enzymes were selected since the absence of these enzymes have been associated with clinically defective lymphoid function
J, Mejer +4 more
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Base editing of organellar DNA with programmable deaminases
Nature Reviews Molecular Cell Biology, 2023Jin-Soo Kim, Jia Chen
exaly