Results 21 to 30 of about 2,664 (174)

Energy metabolism during the maturation of reticulocyte in vitro [PDF]

open access: yes, 1968
1. For the purpose to clarify the mechanism of the revolutional changes in energy metabolism during the reticulocyte maturation the metabolisms of glucose and of the pentose moieties of acid soluble nucleotides have been observed on rabbit reticulocytes ...
Hayashi, Kenji   +5 more
core   +1 more source

DNA replication stress mediates APOBEC3 family mutagenesis in breast cancer [PDF]

open access: yes, 2016
BACKGROUND: The APOBEC3 family of cytidine deaminases mutate the cancer genome in a range of cancer types. Although many studies have documented the downstream effects of APOBEC3 activity through next-generation sequencing, less is known about their ...
Bartek, J   +16 more
core   +8 more sources

The role of dinucleoside polyphosphates on the ocular surface and other eye structures [PDF]

open access: yes, 2016
Dinucleoside polyphosphates comprises a group of dinucleotides formed by two nucleosides linked by a variable number of phosphates, abbreviated NpnN (where n represents the number of phosphates). These compounds are naturally occurring substances present
Carracedo Rodríguez, Juan Gonzalo   +3 more
core   +1 more source

Lymphospecific toxicity in adenosine deaminase deficiency and purine nucleoside phosphorylase deficiency: Possible role of nucleoside kinase(s) [PDF]

open access: yesProceedings of the National Academy of Sciences, 1977
Inherited deficiencies of the enzymes adenosine deaminase (adenosine aminohydrolase; EC 3.5.4.4) and purine nucleoside phosphorylase (purine-nucleoside:orthophosphate ribosyltransferase; EC 2.4.2.1) preferentially interfere with lymphocyte development while sparing most other organ systems.
D A, Carson, J, Kaye, J E, Seegmiller
openaire   +2 more sources

Importance of adenosine-to-inosine editing adjacent to the anticodon in an Arabidopsis alanine tRNA under environmental stress

open access: yes, 2013
In all organisms, transfer RNAs (tRNAs) undergo extensive post-transcriptional modifications. Although base modifications in the anticodon are known to alter decoding specificity or improve decoding accuracy, much less is known about the functional ...
Bock, R., Karcher, D., Zhou, W.
core   +1 more source

Cell cycle regulation and novel structural features of thymidine kinase, an essential enzyme in Trypanosoma brucei [PDF]

open access: yes, 2016
Thymidine kinase (TK) is a key enzyme in the pyrimidine salvage pathway which catalyzes the transfer of the γ-phosphate of ATP to 2′-deoxythymidine (dThd) forming thymidine monophosphate (dTMP).
Ahmad   +69 more
core   +1 more source

Structure-guided discovery of highly efficient cytidine deaminases with sequence-context independence. [PDF]

open access: yesNat Biomed Eng
Xu K   +11 more
europepmc   +2 more sources

136 HIV-1 Nef regulates activity of endoplasmic reticulum chaperone calnexin [PDF]

open access: yes, 2014
HIV-1 Nef promotes viral replication by downmodulating a number of cell surface transmembrane proteins, such as CD4, MHC-I and MHC-II, which are targeted by Nef to various degradation pathways.
Bukrinsky*, Michael   +6 more
core   +1 more source

DNA Methylation Shapes Seed‐Borne Microbiome and Proteome Responses During Early Maize‐Beneficial Bacteria Interactions

open access: yesPlant, Cell &Environment, EarlyView.
ABSTRACT Microorganism and plant interactions are crucial for development and environmental adaptation. Plant growth promoting bacteria enhance agricultural productivity in a sustainable manner, while epigenetic modifications such as DNA methylation regulate gene expression and adaptive responses.
Pedro Igor Zocateli   +12 more
wiley   +1 more source

140 Reversing the Epidemic of HIV-1C in Southern Africa with Treatment as Prevention [PDF]

open access: yes, 2014
The epidemic of HIV-1C in southern Africa is characterized by a sustained prevalence that is substantially higher than for other epidemics of HIV/AIDS. Perhaps the best correlate of transmission is high viral load (HVL), which we target to prevent spread
Essex, M.
core   +1 more source

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