Energy metabolism during the maturation of reticulocyte in vitro [PDF]
1. For the purpose to clarify the mechanism of the revolutional changes in energy metabolism during the reticulocyte maturation the metabolisms of glucose and of the pentose moieties of acid soluble nucleotides have been observed on rabbit reticulocytes ...
Hayashi, Kenji +5 more
core +1 more source
DNA replication stress mediates APOBEC3 family mutagenesis in breast cancer [PDF]
BACKGROUND: The APOBEC3 family of cytidine deaminases mutate the cancer genome in a range of cancer types. Although many studies have documented the downstream effects of APOBEC3 activity through next-generation sequencing, less is known about their ...
Bartek, J +16 more
core +8 more sources
The role of dinucleoside polyphosphates on the ocular surface and other eye structures [PDF]
Dinucleoside polyphosphates comprises a group of dinucleotides formed by two nucleosides linked by a variable number of phosphates, abbreviated NpnN (where n represents the number of phosphates). These compounds are naturally occurring substances present
Carracedo Rodríguez, Juan Gonzalo +3 more
core +1 more source
Lymphospecific toxicity in adenosine deaminase deficiency and purine nucleoside phosphorylase deficiency: Possible role of nucleoside kinase(s) [PDF]
Inherited deficiencies of the enzymes adenosine deaminase (adenosine aminohydrolase; EC 3.5.4.4) and purine nucleoside phosphorylase (purine-nucleoside:orthophosphate ribosyltransferase; EC 2.4.2.1) preferentially interfere with lymphocyte development while sparing most other organ systems.
D A, Carson, J, Kaye, J E, Seegmiller
openaire +2 more sources
In all organisms, transfer RNAs (tRNAs) undergo extensive post-transcriptional modifications. Although base modifications in the anticodon are known to alter decoding specificity or improve decoding accuracy, much less is known about the functional ...
Bock, R., Karcher, D., Zhou, W.
core +1 more source
Cell cycle regulation and novel structural features of thymidine kinase, an essential enzyme in Trypanosoma brucei [PDF]
Thymidine kinase (TK) is a key enzyme in the pyrimidine salvage pathway which catalyzes the transfer of the γ-phosphate of ATP to 2′-deoxythymidine (dThd) forming thymidine monophosphate (dTMP).
Ahmad +69 more
core +1 more source
Structure-guided discovery of highly efficient cytidine deaminases with sequence-context independence. [PDF]
Xu K +11 more
europepmc +2 more sources
136 HIV-1 Nef regulates activity of endoplasmic reticulum chaperone calnexin [PDF]
HIV-1 Nef promotes viral replication by downmodulating a number of cell surface transmembrane proteins, such as CD4, MHC-I and MHC-II, which are targeted by Nef to various degradation pathways.
Bukrinsky*, Michael +6 more
core +1 more source
ABSTRACT Microorganism and plant interactions are crucial for development and environmental adaptation. Plant growth promoting bacteria enhance agricultural productivity in a sustainable manner, while epigenetic modifications such as DNA methylation regulate gene expression and adaptive responses.
Pedro Igor Zocateli +12 more
wiley +1 more source
140 Reversing the Epidemic of HIV-1C in Southern Africa with Treatment as Prevention [PDF]
The epidemic of HIV-1C in southern Africa is characterized by a sustained prevalence that is substantially higher than for other epidemics of HIV/AIDS. Perhaps the best correlate of transmission is high viral load (HVL), which we target to prevent spread
Essex, M.
core +1 more source

