Cationic‐Hydrophilic Di‐Block Copolymers: Surface‐Shielded Vectors for Gene Delivery
This study develops synthetic polycationic di‐block carriers for nucleic acid (NA) delivery in gene therapy. Consisting of a cationic block and a hydrophilic block, these carriers efficiently form complexes with NAs and shield them with a protective bioinert layer, enhancing stability during circulation in the bloodstream while reducing undesirable ...
Eliška Hrdá+4 more
wiley +1 more source
Nanoparticle-assisted strategies in mass spectrometry-based metabolite analysis: recent advances across analytical workflow. [PDF]
Gamboa-Becerra R+5 more
europepmc +1 more source
Purine Molecular Interactions Determine Anisotropic Shape of Zebrafish Biogenic Crystals
Many organisms self‐organize crystals for vision, pigmentation, or storage. In zebrafish, iridophores produce anisotropic crystals in iridosomes. Using imaging and genetic tools, crystal growth is shown to favor the b‐axis, shaped by guanine‐to‐hypoxanthine ratios and hydrogen bonding resulting thereof.
Jannik Rothkegel+4 more
wiley +1 more source
On the Quest for Biomarkers: A Comprehensive Analysis of Modified Nucleosides in Ovarian Cancer Cell Lines. [PDF]
Mohl DA+12 more
europepmc +1 more source
Synthesis of Pyrrole Nucleosides by the Photo-dehydrogenation ofΔ3-Pyrroline Derivatives [PDF]
Masajiro Kawana, Sakae Emoto
openalex +1 more source
Acoustically Responsive Nanofibrous Scaffolds with 3D Hierarchy for Tympanic Membrane Regeneration
This study investigates the influence of molecular, hierarchical, and acoustical stimulation on biofabricated tympanic membrane (TM) scaffolds within a custom‐built bioreactor mimicking the native tissue niche. It demonstrates that synergistically integrated bioactive agents, 3D hierarchical patterns, and sound waves promote the formation of an aligned
Shivesh Anand+5 more
wiley +1 more source
Editorial: Nucleosides, nucleotides and nucleic acids: chemistry and biology
Leandro Soter de Mariz e Miranda+6 more
doaj +1 more source
Preparation of nucleoside analogues: opportunities for innovation at the interface of synthetic chemistry and biocatalysis. [PDF]
Salihovic A+2 more
europepmc +1 more source