Results 231 to 240 of about 197,362 (384)

Cationic‐Hydrophilic Di‐Block Copolymers: Surface‐Shielded Vectors for Gene Delivery

open access: yesJournal of Polymer Science, Volume 63, Issue 6, Page 1419-1432, 15 March 2025.
This study develops synthetic polycationic di‐block carriers for nucleic acid (NA) delivery in gene therapy. Consisting of a cationic block and a hydrophilic block, these carriers efficiently form complexes with NAs and shield them with a protective bioinert layer, enhancing stability during circulation in the bloodstream while reducing undesirable ...
Eliška Hrdá   +4 more
wiley   +1 more source

Nanoparticle-assisted strategies in mass spectrometry-based metabolite analysis: recent advances across analytical workflow. [PDF]

open access: yesMikrochim Acta
Gamboa-Becerra R   +5 more
europepmc   +1 more source

Purine Molecular Interactions Determine Anisotropic Shape of Zebrafish Biogenic Crystals

open access: yesSmall Methods, EarlyView.
Many organisms self‐organize crystals for vision, pigmentation, or storage. In zebrafish, iridophores produce anisotropic crystals in iridosomes. Using imaging and genetic tools, crystal growth is shown to favor the b‐axis, shaped by guanine‐to‐hypoxanthine ratios and hydrogen bonding resulting thereof.
Jannik Rothkegel   +4 more
wiley   +1 more source

On the Quest for Biomarkers: A Comprehensive Analysis of Modified Nucleosides in Ovarian Cancer Cell Lines. [PDF]

open access: yesCells
Mohl DA   +12 more
europepmc   +1 more source

Acoustically Responsive Nanofibrous Scaffolds with 3D Hierarchy for Tympanic Membrane Regeneration

open access: yesSmall Structures, EarlyView.
This study investigates the influence of molecular, hierarchical, and acoustical stimulation on biofabricated tympanic membrane (TM) scaffolds within a custom‐built bioreactor mimicking the native tissue niche. It demonstrates that synergistically integrated bioactive agents, 3D hierarchical patterns, and sound waves promote the formation of an aligned
Shivesh Anand   +5 more
wiley   +1 more source

Editorial: Nucleosides, nucleotides and nucleic acids: chemistry and biology

open access: yesFrontiers in Chemistry
Leandro Soter de Mariz e Miranda   +6 more
doaj   +1 more source

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