Results 211 to 220 of about 82,908 (301)

Efficacy of dolutegravir/lamivudine in adults with HIV‐1 and isolated reactive hepatitis B core antibody: Insights from Phase 3/3b study results

HIV Medicine, EarlyView.
Abstract Objectives As two‐drug HIV‐1 antiretroviral therapy (ART) regimens become standard, data gaps remain concerning their safety and efficacy among people with isolated reactive hepatitis B core antibodies (anti‐HBc). Here, we assessed the safety and efficacy of dolutegravir/lamivudine (DTG/3TC) versus three‐ or four‐drug regimens (3DRs/4DRs ...
D. Fox, J. Slim, E. T. Overton, A. Doblado‐Maldonado, P. Jeffery, R. A. Grove, S. D. Advani, R. Borsi, C. M. Parry, M. Underwood, B. Jones   +10 more
wiley   +1 more source

Coapplication of Adenine with Inosine or Guanosine Supports Rapid ATP Restoration by ATP-deprived Cultured Primary Astrocytes. [PDF]

Neurochem Res
Karger G, Dringen R.
europepmc   +1 more source

Systematic screening for age‐related comorbidities: Health care optimization among persons with HIV in an outpatient setting

HIV Medicine, EarlyView.
Abstract Background Age‐related comorbidities occur earlier and more frequently in people with HIV (PWH) than in the general population and have emerged as a key challenge in long‐term HIV care. Unfortunately, many of these conditions remain undiagnosed, and systematic screening in clinical practice remains limited.
Anna Katrine Haslund Roed, Anne‐Mette Lebech, Sabine Singh, Ole Kirk, Susanne Dam Nielsen   +4 more
wiley   +1 more source

Optimization of <i>q</i> Value for Sensitive Detection of Uridine and Thymidine Nucleosides by MS³. [PDF]

J Am Soc Mass Spectrom
Duan Z, Wang C, Wang Y.
europepmc   +1 more source

Real‐world clinical and laboratory changes after switching to two‐drug regimen in HIV‐suppressed individuals: 48 weeks and beyond

HIV Medicine, EarlyView.
Abstract Introduction Two‐drug regimens (2DRs) may reduce long‐term drug toxicities and drug‐drug interactions for people with HIV (PWH) on antiretroviral therapy (ART). This study evaluated clinical and laboratory outcomes in PWH who switched from standard ART to dolutegravir and lamivudine (DTG + 3TC) in real‐world settings.
Tommy Hing‐cheung Tang, Ruby Tsz‐shan Kwong, Phillip Chan, Kwok‐wai Lam, Helen Shuk‐ying Chan, Man‐yee Chu, Wilson Lam, Tak‐chiu Wu, Wai‐shing Leung, Sai‐kwong Yung, Wan‐man Ting, Annabel Kai‐tung Choy, Joe Lok‐fung Tung, Jason Ka‐wah Fong, Daniel Kai‐yeung Yeung, Man‐po Lee   +15 more
wiley   +1 more source

An mRNA-based FimH nanoparticle vaccine against uropathogenic <i>Escherichia coli</i> is highly immunogenic in rodents. [PDF]

Front Immunol
Roier S, Adamo R, Rosini R, Pezzicoli A, Scarselli M, Petsch B, Jasny E, Rauch S.   +7 more
europepmc   +1 more source

Klebsiella sp. strain B7 enhances alkaline tolerance by secreting pyruvic acid to accelerate L‐malic acid accumulation in soybean

Journal of Integrative Plant Biology, EarlyView.
Klebsiella sp. strain B7 acts as a positive regulator in alkaline stress responses in soybean. By activating pyruvic acid metabolism and L‐malic acid biosynthesis pathways, B7 significantly increases alkaline tolerance and yield in soybean. ABSTRACT Alkaline stress is a major constraint on crop growth and development and negatively impacts soybean ...
Yingxue Cao, Yijia Jiang, Yang Li, Yong Long, Siyu Huang, Hongwei Li, Miao Yang, Mingyu Yang, Yuecheng Tang, Bo Zhang, Zhongming Fang, Ming Yuan, Zhenhua Yu, Fanli Meng   +13 more
wiley   +1 more source

A Dual Luminescent and Chromogenic Pt-NCN Complex for the Detection of GTP and CTP in Aqueous Media. [PDF]

Inorg Chem
Valdes-García J, Vonlanthen M, Cuétara-Guadarrama F, Garcia-Bassoco D, Valdés-Negrín HL, López-Pérez A, Rivera E, Hernández-Ortega S, Dorazco-González A.   +8 more
europepmc   +1 more source

Key metabolites secreted by Chlorella vulgaris alleviate salt stress in soybean seedlings

Journal of Integrative Plant Biology, EarlyView.
Chlorella vulgaris secretes exosome‐derived linolenic acid and inosine, which alleviate salt stress and enhance salt tolerance in soybean seedlings by activating stress‐responsive signaling networks. ABSTRACT Soil salinization is a major abiotic stress factor that reduces soybean production.
Yunyi Shi, Ruitong Chen, Kai Jiang, Aijuan Jiang, Jianchao Yang, Hongli Cui, Min Chen   +6 more
wiley   +1 more source