Results 201 to 210 of about 58,095 (298)

Transgenic selection and underlying mechanisms in apicomplexan parasites

The FEBS Journal, EarlyView.
Transgenic selection markers have driven genetic engineering in apicomplexans, enabling precise, iterative experiments. This review discusses mechanistic details of drug selection markers, strategies for marker recycling, and practical considerations for several clinically relevant parasites.
Swaroop Peddiraju, Rakhee Lohia, Nishith Gupta   +2 more
wiley   +1 more source

Zinc Nanobiohybrid-Catalyzed Hydrolysis of <i>N</i>‑Glycosidic Bond of Uridine to Uracil and Derivatives by a Photo-Fenton Oxidation. [PDF]

ACS Omega
Garcia-Sanz C, Losada-Garcia N, Palomo JM.   +2 more
europepmc   +1 more source

Hydrothermal origin of metabolic phosphorylation

The FEBS Journal, EarlyView.
Serpentinizing hydrothermal vents are candidate sites for biochemical origins. They generate extremely reducing conditions, depositing phosphite (HPO32−) and transition metals, including palladium, in the native (zero‐valent) state. Schlikker et al.
Manon L. Schlikker, Nadja K. Hoffmann, Sabine Metzger, Jorge Moral‐Pombo, Harun Tüysüz, William F. Martin   +5 more
wiley   +1 more source

A versatile strategy for oligonucleotide functionalization via on-support phosphitylation. [PDF]

Nat Chem
Dasgupta A, Golojuch S, Xiao L, Fahmi NE, Anderson EA, Brown T.   +5 more
europepmc   +1 more source

Toward a minimal amino acid alphabet for protein design

The FEBS Journal, EarlyView.
Proteins are built from 20 canonical amino acids; however, it is interesting to investigate whether they can also be formed from reduced amino acid alphabets. Using protein design, we designed proteins based on all alphabets comprising 2 to 10 ‘early’ amino acids (those likely to have been present before the origin of life).
Karel Půbal, Kseniia Kushnir, Vojtěch Spiwok, Karolína Loužecká, Vladimír Setnička, Petra Lipovová   +5 more
wiley   +1 more source

Heck-type C-glycosylations in the synthesis of artificial nucleotides and functional nucleic acids. [PDF]

RSC Chem Biol
Dörrenhaus R, Zenz A, Kath-Schorr S.
europepmc   +1 more source

Dietary counselling and exercise training for lipid management in people living with HIV: A systematic review and meta‐analysis

HIV Medicine, EarlyView.
Abstract Objectives Dyslipidaemia is highly prevalent among people living with human immunodeficiency virus (HIV) and contributes to increased cardiovascular risk. Although lifestyle interventions are recommended, evidence specific to people living with HIV remains limited. Previous reviews have primarily focused on dietary interventions or low‐density
Maki Aomori, Hitomi Maeda
wiley   +1 more source

Cuprous Ions Binding to Cytosine and Guanine Oligonucleotides. [PDF]

Chembiochem
Pereira J, Brachet M, Barthélémy P, Alies B.   +3 more
europepmc   +1 more source

Stability of the HIV cascade of care throughout the COVID‐19 pandemic in Europe: Results from the multinational EuroSIDA cohort study (2016–2022)

HIV Medicine, EarlyView.
Abstract Background Prior to the COVID‐19 pandemic, antiretroviral therapy (ART) coverage and viral suppression were improving across Europe; however, the impact of the pandemic on HIV care remains uncertain. Methods In‐person visits, ART coverage and viral suppression among those on ART were described in the EuroSIDA cohort for each calendar year from
Olga Fursa, Wendy Bannister, Giovanni Guaraldi, Justyna Kowalska, Jose M. Miro, Robert Zangerle, David Jilich, Jean‐Paul Viard, Katharina Kusejko, Piotr Nowak, Pere Domingo, Claire Mackintosh, Antonella Castagna, Thomas Benfield, Bartosz Szetela, Johannes Bogner, Marta Boffito, Lars Peters, on behalf of the EuroSIDA study group   +18 more
wiley   +1 more source