Results 201 to 210 of about 130,320 (304)

Combined Effects of Romosozumab and Zoledronate on the Development of Osteonecrosis of the Jaw

Oral Diseases, EarlyView.
ABSTRACT Objective This study aimed to assess the occurrence of medication‐related osteonecrosis of the jaw (MRONJ) in mice following the sequential administration of romosozumab and zoledronate and to confirm their inhibitory effects on osteoclast differentiation in vitro.
Hae‐Seo Park, Shihyun Kim, Seo‐Yeong An, Reuben H. Kim, Jongho Choi, Moon‐Young Kim   +5 more
wiley   +1 more source

A comprehensive analysis of the use of nucleoside analogues in RNA therapeutics. [PDF]

J Transl Med
Kukushkina-Zvezdova AA, Zherebtsova AA, Telegina DV, Skvortsov IA, Ivanov RA, Reshetnikov VV.   +5 more
europepmc   +1 more source

Mapping and Functional Characterization of Homologous Genes AhSUCA06 and AhSUCA16 Underlying Sucrose, Oil and Protein Contents in Peanut (Arachis hypogaea L.)

Plant Biotechnology Journal, EarlyView.
ABSTRACT Cultivated peanut (Arachis hypogaea L.) is an important oilseed and cash crop, and seed sucrose content (SSC), seed oil content (SOC) and seed protein content (SPC) are key determinants of seed flavour, texture, and overall quality. Identifying quantitative trait loci (QTLs) and candidate genes associated with SSC, SOC and SPC is therefore of ...
Yuzhen Zheng, Feiyan Qi, Lei Shi, Ziqi Sun, Hongfei Liu, Hua Liu, Li Qin, Juan Wang, Chenyang Zhi, Mengmeng Wang, Ziqiang Mo, Stefano Pavan, Xiao Wang, Yaojun Hu, Huanhuan Zhao, Xiaona Li, Wenzhao Dong, Meng Zhang, XiaoDong Dai, Zheng Zheng, Xinyou Zhang   +20 more
wiley   +1 more source

Doxecitine and Doxribtimine: First Approval. [PDF]

Paediatr Drugs
Blair HA.
europepmc   +1 more source

Virocell Necromass Provides Limited Plant Nitrogen and Elicits Rhizosphere Metabolites That Affect Phage Dynamics

Plant, Cell &Environment, EarlyView.
ABSTRACT Bacteriophages impact soil bacteria through lysis, altering the availability of organic carbon and plant nutrients. However, the magnitude of nutrient uptake by plants from lysed bacteria remains unknown, partly because this process is challenging to investigate in the field.
Vlastimil Novak, Michelle C. M. van Winden, Thomas V. Harwood, Rachel Neurath, Suzanne M. Kosina, Katherine B. Louie, Matthew B. Sullivan, Simon Roux, Karsten Zengler, Vivek K. Mutalik, Trent R. Northen   +10 more
wiley   +1 more source

Pentose bisphosphate pathway can act in central metabolism for nucleoside-dependent growth of <i>Thermococcus kodakarensis</i> strains. [PDF]

Appl Environ Microbiol
Nishida T, Chen Y, Azuma T, Orita I, Fukui T.   +4 more
europepmc   +1 more source

DNA Methylation Shapes Seed‐Borne Microbiome and Proteome Responses During Early Maize‐Beneficial Bacteria Interactions

Plant, Cell &Environment, EarlyView.
ABSTRACT Microorganism and plant interactions are crucial for development and environmental adaptation. Plant growth promoting bacteria enhance agricultural productivity in a sustainable manner, while epigenetic modifications such as DNA methylation regulate gene expression and adaptive responses.
Pedro Igor Zocateli, Geovanna Vitória Olímpio, Felipe Astolpho de Almeida, Letícia Oliveira da Rocha, Diego Vinicius de Sena Martins, Sara Sangi, Fábio Lopes Olivares, Elyabe Monteiro de Matos, Juliana Siqueira, Lyderson Facio Viccini, Roberta Pena da Paschoa, Vanildo Silveira, Clícia Grativol   +12 more
wiley   +1 more source

Long‐Term Salt Exposure Reprograms the Nicotiana tabacum BY‐2 Suspension Proteome and Metabolome Toward Stabilization of the Core Metabolic Pathways, Protein Turnover Machinery Modifications, and Protective Metabolome Adjustments

Plant, Cell &Environment, EarlyView.
ABSTRACT In this study, we analyzed a unique Nicotiana tabacum BY‐2 line that was gradually adapted to and subsequently maintained in 190 mM NaCl for over 15 years. Years of continuous high salinity shaped a stable “new homeostasis” in BY‐2 suspension cells. Salt‐adapted cells were smaller and formed tighter clusters. Metabolomics revealed constitutive
Anita Rzadkiewicz, Łukasz Marczak, Aleksander Strugała, Maria Tomys, Ewelina Ratajczak, Tomasz Skrzypczak, Przemysław Wojtaszek, Anna Kasprowicz‐Maluśki, Agnieszka Szuba   +8 more
wiley   +1 more source

Space ionizing radiation triggers the formation of peptides and organophosphates on olivine surfaces. [PDF]

Nat Commun
Ding R, Qiu S, Guo X, Zhang M, Liu Y, Zou Z, Ying J, Zhang M, Zhang B, Zhao Y.   +9 more
europepmc   +1 more source

Electromechanical modelling and simulation of human‐induced pluripotent stem cell‐derived cardiomyocytes predict drug‐induced contractility effects

The Journal of Physiology, EarlyView.
Abstract figure legend A study described in this paper describes a new tool for hiPSC‐CM electromechanical behaviour simulations using mathematical modelling. The model enables in silico assays making drug testing quick, comprehensive and accurate. New hiPSC‐CM models can be used as a platform to integrate in vitro and in silico findings.
Milda Folkmanaite, Xin Zhou, Andreas Koschinski, Wan‐Hua Hong, Marilù Casini, Manuel Koch, Ursula Ravens, Remi Peyronnet, Manuela Zaccolo, Blanca Rodriguez   +9 more
wiley   +1 more source