Results 251 to 260 of about 197,362 (384)

Acid- and base-catalyzed ring-opening reactions or a sterically hindered epoxide [PDF]

, 1987
Bäuml, Englbert, Koschinsky, Rainer, Mayr, Herbert, Will, Elfriede   +3 more
core   +1 more source

Chronic Cellular NAD Depletion Activates a Viral Infection‐Like Interferon Response Through Mitochondrial DNA Leakage

Aging Cell, EarlyView.
Chronic NAD depletion in fibroblasts lowers NAD levels, increases mitochondrial mass, and triggers an interferon‐dependent inflammatory response via mtDNA leakage through VDAC1, activating the cGAS‐STING pathway. This links NAD deficiency to metabolic and inflammatory processes, with implications for diseases associated with NAD decline.
Claudia C. S. Chini, Laura Colman, Eduardo Palmieri, Jessica L. Strange, Sonu Kashyap, Bing Han, Andres Benitez‐Rosendo, Gina L. Ciccio Lopez, Sara Peixoto Rabelo, Shreyartha Mukherjee, Gustavo H. de Souza, John Varga, Ralph G. Meyer, Mirella L. Meyer‐Ficca, Eduardo N. Chini   +14 more
wiley   +1 more source

Ionization of DNA Nucleotides in Explicit Solution. [PDF]

Molecules
Bai J, Zhang Y, Yin S, Che L, Yang S.
europepmc   +1 more source

Avian Lifespan Network Reveals Shared Mechanisms and New Key Players in Animal Longevity

Aging Cell, EarlyView.
In this work, we found that birds with similar lifespans exhibit convergent evolution in specific genes, suggesting that shared evolutionary pressures shape the genetic basis of lifespan similarity across species. By investigating protein–protein interactions across genes evolving convergently in long‐ and short‐lived species, we identified a network ...
Mirko Martini, Giovanni Piccinini, Liliana Milani, Mariangela Iannello   +3 more
wiley   +1 more source

Modeling and Optimization of Microwave Vacuum Drying for Pinelliae Rhizoma: Integrating Drying Kinetics, Artificial Neural Networks, and Quality Preservation. [PDF]

Food Sci Nutr
Wang P, Yang X, Huang X, Ma G, Zhang S, Wang S, Wang M, Zhu Z, Xu Y, Zang Z, Liu X.   +10 more
europepmc   +1 more source

Nucleoside phosphate levels in normal and tumour cells and their significance.

, 1969
Peter C. Jones
openalex   +2 more sources

Synthesis of 1’-N-homoazanucleosides as potential transition state analogues and antiviral agents [PDF]

, 2016
Bouton, Jakob, Van Calenbergh, Serge
core  

A Metabolite Score of Unintentional Weight Loss Explained a Substantial Proportion of Associated Mortality and Mobility Limitation Risk in a Biracial Older Cohort

Aging Cell, EarlyView.
A metabolite‐based score for short‐term unintentional weight loss was independently associated with mortality and mobility limitation risks in healthy older adults. It accounted for over 20% of the excess risk linked to unintentional weight loss, independent of lifestyle and medical history, suggesting a shared metabolic mechanism that remains ...
Shanshan Yao, Megan M. Marron, Samaneh Farsijani, Iva Miljkovic, George C. Tseng, Ravi V. Shah, Venkatesh L. Murthy, Anne B. Newman   +7 more
wiley   +1 more source

Mediated Electrochemical Oxidation of Nucleosides to Their 5'-Carboxylic Acid Derivatives. [PDF]

Chemistry
Abrams DJ, Johnson MR, Lacker CR, Yoon TP, Martinelli JR, Stahl SS.   +5 more
europepmc   +1 more source

Studies of Nucleosides and Nucleotides. XXIII. A Versatile Method for Replacement of 6-Hydroxyl Group of Purine Nucleoside.

, 1964
Morio Ikehara, Hitoshi Uno, Fumiyoshi Ishikawa   +2 more
openalex   +2 more sources