Results 251 to 260 of about 198,787 (385)

Preclinical Evaluation of a Novel Molecule Targeting Nucleoside Homeostasis to Restore Energy Metabolism and Cognitive Function in Alzheimer's Disease. [PDF]

Pharmacol Res Perspect
Wu KC, Lin CY, Tran T, Lin JH, Yeh HH, Ho CJ, Chern Y, Lin CJ.   +7 more
europepmc   +1 more source

Acid- and base-catalyzed ring-opening reactions or a sterically hindered epoxide [PDF]

, 1987
Bäuml, Englbert, Koschinsky, Rainer, Mayr, Herbert, Will, Elfriede   +3 more
core   +1 more source

The role of DNA in RNA synthesis, IX. Nucleoside triphosphate termini in RNA polymerase products.

, 1965
Umadas Maitra, H Hurwitz
openalex   +1 more source

Comparative lipidomic and proteomic analysis reveals species‐specific differences in midgut composition and insecticide absorption between Apis mellifera and Bombus terrestris

Pest Management Science, EarlyView.
Lipidomic and proteomic analysis revealed large‐scale differences in the midgut composition of the honeybee Apis mellifera and the buff‐tailed bumblebee Bombus terrestris. These differences correlated to increased insecticide absorption in the bumblebee when using an ex vivo Ussing chamber and subsequently in vivo feeding assay (created in Biorender ...
Emmanouil Kokkas, Joseph Hawkins, Lauraine Swindale, Aniko Kende, John Sinclair, Jacob M Riveron, Helen Thompson, Adam Pym   +7 more
wiley   +1 more source

Landscape of targets within nucleoside metabolism for the modification of immune responses. [PDF]

Front Oncol
Dunderdale EM, Abt ER.
europepmc   +1 more source

A Population Pharmacokinetic Approach to Understand the Effect of Efavirenz on CYP3A Activity in Healthy Volunteers Using Midazolam as a Probe

CPT: Pharmacometrics &Systems Pharmacology, EarlyView.
ABSTRACT Efavirenz induces and inhibits multiple drug‐metabolizing enzymes, contributing to significant drug–drug interactions. This study quantified the impact of multiple doses of efavirenz on CYP3A activity via midazolam metabolism using a population pharmacokinetic approach.
Kimberly S. Collins, Blessed W. Aruldhas, Ingrid F. Metzger, Jessica B. L. Lu, Michael A. Heathman, Sara K. Quinney, Zeruesenay Desta   +6 more
wiley   +1 more source

HR-MS Analysis of the Covalent Binding of Edaravone to 5-Formylpyrimidine Bases and a DNA Oligonucleotide Containing a 5-Formylcytidine Residue. [PDF]

Rapid Commun Mass Spectrom
Regnault R, Kouach M, Goossens L, Thuru X, Bailly C, Goossens JF.   +5 more
europepmc   +1 more source

Synthesis of 1’-N-homoazanucleosides as potential transition state analogues and antiviral agents [PDF]

, 2016
Bouton, Jakob, Van Calenbergh, Serge
core  

ALKBH8-mediated formation of a novel diastereomeric pair of wobble nucleosides in mammalian tRNA.

Nature Communications, 2011
E. van den Born, C. Vågbø, Lene Songe-Møller, Vibeke Leihne, G. F. Lien, G. Leszczynska, A. Małkiewicz, H. Krokan, F. Kirpekar, A. Klungland, P. Falnes   +10 more
semanticscholar   +1 more source

Ashwagandha: Is It Safe? Part 2: A Preclinical Evidence Review

Phytotherapy Research, EarlyView.
ABSTRACT The preclinical evidence for the safety of ashwagandha (Withania somnifera (L.) Dunal, AS) is reviewed, and its preparations (extracts) and constituents, from the general toxicity in animal models to in vitro and cell culture studies, which may elucidate mechanisms of action and explain clinical case reports.
Elizabeth M. Williamson, Thomas Brendler
wiley   +1 more source