Results 231 to 240 of about 64,059 (299)

Anti-histone and anti-nucleosome rather than anti-dsDNA antibodies associate with IFN-induced biomarkers in Sudanese and Swedish SLE patients. [PDF]

Rheumatology (Oxford)
Elbagir S, Mohammed NA, Oke V, Larsson A, Nilsson J, Elshafie A, Elagib EM, Nur MAM, Gunnarsson I, Svenungsson E, Rönnelid J.   +10 more
europepmc   +1 more source

The action of chymotrypsin on nucleosome cores. Histone products and conformational effects of limited digestion.

, 1986
Nancy Lynn Rosenberg, Rachel M. Smith, Randolph L. Rill   +2 more
openalex   +1 more source

Chromatin fibers observed in situ in frozen hydrated sections. Native fiber diameter is not correlated with nucleosome repeat length. [PDF]

, 1994
C. L. F. Woodcock
openalex   +1 more source

What's in a name: the multifaceted function of DNA‐ and RNA‐binding proteins in T cell responses

The FEBS Journal, Volume 292, Issue 8, Page 1853-1867, April 2025.
In this state‐of‐the‐art review, we describe how DNA‐ and RNA‐binding proteins (DRBPs) may bind both DNA and RNA and discuss the putative functional relevance of this dual binding. Furthermore, we perform an exploratory analysis into protein domains that are associated with DRBPs.
Kaspar Bresser, Branka Popović, Monika C. Wolkers   +2 more
wiley   +1 more source

The transactivation domain of Pho4 is required for nucleosome disruption at the PHO5 promoter. [PDF]

, 1994
John Svaren, Judith Schmitz, Wolfram Hörz   +2 more
openalex   +1 more source

Notch dependent chromatin remodeling enables Gata3 binding and drives lineage specific CD8+ T cell function

Immunology &Cell Biology, Volume 103, Issue 4, Page 365-382, April 2025.
This study examines how Notch signaling conditions the genome landscape within activated CD8+ T cells in such a way to alter the binding pattern of transcription factors such as Gata3. This Notch dependent conditioning directs Gata3 binding to CD8+ T cell lineage specific gene loci enabling generation of effective T cell responses.
Jessie O'Hara, Pushkar Dakle, Michelle Ly Thai Nguyen, Adele Barugahare, Taylah J Bennett, Vibha AV Udupa, Nicholas Murray, Gemma Schlegel, Constantine Kapouleas, Jasmine Li, Stephen J Turner, Brendan E Russ   +11 more
wiley   +1 more source

Structural insights into how Cas9 targets nucleosomes. [PDF]

Nat Commun
Nagamura R, Kujirai T, Kato J, Shuto Y, Kusakizako T, Hirano H, Endo M, Toki S, Saika H, Kurumizaka H, Nureki O.   +10 more
europepmc   +1 more source

Artificial nucleosome positioning sequences.

, 1989
Thomas E. Shrader, Donald M. Crothers
openalex   +1 more source

IRX5 Promoted SREBP1‐Mediated de Novo Fatty Acid Synthesis via HMGN4 in Hepatocellular Carcinoma

Journal of Cellular and Molecular Medicine, Volume 29, Issue 7, April 2025.
ABSTRACT Hepatocellular carcinoma (HCC), a prevalent malignant tumour, ranks highly in both morbidity and mortality, and its prevention and treatment need further studies. The transcription factor iroquois homeobox 5 (IRX5) plays an essential role in HCC, whereas little is known about its exact functions and underlying mechanisms in tumour metabolism ...
Liying Zhu, Yongjie Xu, Changyudong Huang, Chengcheng Li, Yiqiong Zhang, Xing Li, Wei Pan, Zhu Zeng   +7 more
wiley   +1 more source

Transfer learning reveals sequence determinants of the quantitative response to transcription factor dosage. [PDF]

Cell Genom
Naqvi S, Kim S, Tabatabaee S, Pampari A, Kundaje A, Pritchard JK, Wysocka J.   +6 more
europepmc   +1 more source