Results 231 to 240 of about 156,001 (374)
Parasite nucleosomes: Chromatin dynamics rewired. [PDF]
Deák G, Wilson MD.
europepmc +1 more source
Histone Acetylation Status and DNA Sequence Modulate ATP-dependent Nucleosome Repositioning [PDF]
Władysław Krajewski
openalex +1 more source
The study identifies TRIM15 as a key driver in the development of obesity‐associated esophageal adenocarcinoma (EAC). Mechanistically, TRIM15 degrades YY2 through the proteasome pathway, suppressing FOXRED1 transcription and ultimately accelerating tumor proliferation.
Haohui Wang +10 more
wiley +1 more source
Genome-wide Map of Nucleosome Acetylation and Methylation in Yeast
Dmitry Pokholok +13 more
semanticscholar +1 more source
In contrast to the adult mammalian heart, which lacks regenerative capacity, the neonatal heart retains a transient regenerative capacity. In this study, high mobility group box 2 (HMGB2) is identified as a crucial protein driving heart regeneration based on comprehensive analyses using quantitative proteomics with tandem mass tag (TMT) labelling, RNA ...
Liu‐Hua Zhou +17 more
wiley +1 more source
BRD4 Phosphorylation Regulates the Structure of Chromatin Nanodomains. [PDF]
Seitz C, Fu D, Liu M, Ma H, Liu J.
europepmc +1 more source
The Handedness of Nucleosomes is Governed by the Supercoiling of DNA [PDF]
Sung Hyun Kim +5 more
openalex +1 more source
Genome‐wide, high‐resolution profiling of hydroxymethylation in mouse SCNT embryos reveals a transient, allele‐symmetric 5hmC reprogramming pattern distinct from natural embryos, with X‐chromosomes and imprinting control regions resistant to proper remodeling.
Zeming Xiang +9 more
wiley +1 more source
G34R cancer mutation alters the conformational ensemble and dynamics of the histone H3.3 tails. [PDF]
Fuchs HA +6 more
europepmc +1 more source
Geometrically Encoded Positioning of Introns, Intergenic Segments, and Exons in the Human Genome
This study introduces a new hypothesis: exons, introns, and intergenic segments are non‐random projections of the functional layers of 3D structure of chromatin packing domains. Evidence is presented that this “geometric code” may encode volumetric structure, reconciling epigenetic patterns, correlates with oncogenic mutations, acting as a potential ...
Luay M. Almassalha +11 more
wiley +1 more source

