Results 301 to 310 of about 156,001 (374)

Propionibacterium acnes evades microbicidal phagocytosis by inhibiting the mitochondrial biogenesis of nucleus pulposus cells

open access: yesThe FEBS Journal, Volume 293, Issue 1, Page 295-317, January 2026.
P. acnes infection impairs the mitochondrial biogenesis of nucleus pulposus cells (NPCs) through the AMPK/SIRT‐1/PGC‐1α signaling pathway. This results in impaired mitochondria that are unable to generate sufficient ATP, and impaired delivery of mitochondrial reactive oxygen species to carry out the bactericidal process effectively.
Lemeng Ren   +9 more
wiley   +1 more source

Lysine demethylase 4A: from chromatin to centrosomes

open access: yesThe FEBS Journal, Volume 293, Issue 2, Page 392-395, January 2026.
The lysine demethylase 4A (KDM4A) remodels chromatin by histone demethylation, regulating gene expression. In this issue, Chowdhury et al. report a previously undescribed localisation for KDM4A outside the nucleus, at the pericentriolar material around the centrosome.
Anushka Sharma   +2 more
wiley   +1 more source

Mechanisms of RNF168 nucleosome recognition and ubiquitylation

open access: hybrid
Qi Hu   +6 more
openalex   +1 more source

SWI/SNF Chromatin Remodelling Complex in Hepatic Physiology: Mechanistic Insights Into Development, Homeostasis and Pathogenesis

open access: yesJournal of Cellular and Molecular Medicine, Volume 30, Issue 2, January 2026.
ABSTRACT The liver executes essential metabolic functions including energy homeostasis, lipid biosynthesis, cholesterol regulation and xenobiotic detoxification. While hepatocyte metabolic activity forms the foundation of these processes, their precise regulation is achieved through chromatin remodelling mechanisms, with the SWI/SNF complex emerging as
Rui Li   +4 more
wiley   +1 more source

Molecular and epistatic interactions between pioneer transcription factors shape nucleosome dynamics and cell differentiation. [PDF]

open access: yesNat Commun
Coux RX   +6 more
europepmc   +1 more source

Experimental Evidence That Prenatal and Postnatal Developmental Stress Affects the Adult Seminal Fluid Proteome in a Precocial Bird

open access: yesMolecular Ecology, Volume 35, Issue 2, January 2026.
ABSTRACT Seminal fluid proteins are important modulators of male fertility and reproductive success, yet little is known about how their abundance responds to early‐life developmental stress. Japanese quail Coturnix japonica) males produce a unique seminal foam that enhances fertilisation success.
Chloe Mason   +6 more
wiley   +1 more source

Chromatin‐associated DEK proteins maintain H3K27me3 balance and coordinate developmental transitions in plants

open access: yesNew Phytologist, Volume 249, Issue 2, Page 930-944, January 2026.
Summary Chromatin organization and histone modifications play essential roles in regulating gene expression during development. DEK is a conserved chromatin‐associated protein implicated in DNA topology and transcriptional regulation, yet its in vivo function in plants has remained elusive.
Miyuki Nakamura   +8 more
wiley   +1 more source

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