Results 301 to 310 of about 141,257 (371)

Neutrophil Extracellular Traps Are Widely Distributed Across Lesional and Perilesional Hidradenitis Suppurativa Skin, and Elevated Serum NET Markers Associate With Moderate to Severe HS Disease

open access: yesInternational Journal of Dermatology, Volume 64, Issue 7, Page 1234-1241, July 2025.
Increased NET markers are detected in HS skin and blood. Neutrophils are scarce in healthy skin but infiltrate lesions of hidradenitis suppurativa (HS) patients. Activated neutrophils release proinflammatory neutrophil extracellular traps (NETs). The NET marker CitH3 was widely distributed across both lesional and perilesional regions of HS skin but ...
Stephanie C. M. van Dalen   +12 more
wiley   +1 more source

BAF60/SWP73 subunits define subclasses of SWI/SNF chromatin remodelling complexes in Arabidopsis

open access: yesNew Phytologist, Volume 247, Issue 2, Page 791-812, July 2025.
Summary Evolutionarily conserved switch‐defective/sucrose nonfermentable (SWI/SNF) ATP‐dependent chromatin remodelling complexes (CRCs) alter nucleosome positioning and chromatin states, affecting gene expression to regulate important processes such as proper development and hormonal signalling pathways.
Sebastian P. Sacharowski   +23 more
wiley   +1 more source

ISDH‐seq: a robust methodology for profiling and characterization of open chromatin

open access: yesPlant Biotechnology Journal, Volume 23, Issue 7, Page 2512-2525, July 2025.
Summary Profiling of open chromatin is essential for understanding regulatory mechanisms that govern DNA‐templated events. However, methodology‐dependent detection of open chromatin sites (OCSs) has been reported in both humans and plants. Therefore, there is a pressing need for any reliable orthogonal methodologies to broaden the identification of ...
Zhaoguo Li   +8 more
wiley   +1 more source

The Plant Mind: Unraveling Abiotic Stress Priming, Memory, and Adaptation

open access: yesPhysiologia Plantarum, Volume 177, Issue 4, July/August 2025.
ABSTRACT Plants exhibit a remarkable capacity to adapt to recurrent abiotic stresses, prompting a re‐evaluation of traditional views on plant responses to environmental challenges. This review explores the intricate mechanisms of stress priming, memory, and adaptation in plants.
K. P. R. Aswathi   +5 more
wiley   +1 more source

The Direct and Individual Transcriptional Function of the Human Homodimeric and Heterodimeric Basic Helix–Loop–Helix Transcription Factors E47 and Scleraxis

open access: yesThe FASEB Journal, Volume 39, Issue 12, 30 June 2025.
The isolated yeast model allowed visualization of the function of the heterodimeric SCX and E47 transcription factors (TFs) in the absence of other interacting proteins. The findings support the need for additional transcription factor binding sites (TFBS) and a permissive chromatin landscape for these TFs to exert a positive transcriptional effect ...
Karla Miranda López‐Delucio   +5 more
wiley   +1 more source

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