Results 261 to 270 of about 72,215 (324)
Management of T‐cell malignancies: Bench‐to‐bedside targeting of epigenetic biology
Abstract The peripheral T‐cell lymphomas (PTCL) are the only disease for which four histone deacetylase (HDAC) inhibitors have been approved globally as single agents. Although it is not clear why the PTCL exhibit such a vulnerability to these drugs, understanding the biological basis for this activity is essential.
Ariana Sabzevari+7 more
wiley +1 more source
SMAdd-seq: probing chromatin accessibility with small molecule DNA intercalation and nanopore sequencing. [PDF]
Bai G+10 more
europepmc +1 more source
Selective Anchoring of TFIID to Nucleosomes by Trimethylation of Histone H3 Lysine 4
M. Vermeulen+9 more
semanticscholar +1 more source
ABSTRACT Rationale Edaravone (EDA) is a radical scavenger and an antioxidant drug approved to treat amyotrophic lateral sclerosis and used as a research tool to explore treatment of neurodegenerative diseases and cancers. It is also a reactive agent, known as PMP (1‐phenyl‐3‐methyl‐5‐pyrazolone), used for the analysis of polysaccharides composition ...
Romain Regnault+5 more
wiley +1 more source
The WAC-downWAC domain in the yeast ISW2 nucleosome remodeling complex forms a structural module essential for ISW2 function but not cell viability. [PDF]
Singh AK+3 more
europepmc +1 more source
Force transmission through the inner kinetochore is enhanced by centromeric DNA sequences. [PDF]
Miedlar E+9 more
europepmc +1 more source
MeCP2 requires interactions with nucleosome linker DNA to read chromatin DNA methylation
Watson JA+9 more
europepmc +1 more source