Results 261 to 270 of about 72,215 (324)

Management of T‐cell malignancies: Bench‐to‐bedside targeting of epigenetic biology

open access: yesCA: A Cancer Journal for Clinicians, Volume 75, Issue 4, Page 282-307, July/August 2025.
Abstract The peripheral T‐cell lymphomas (PTCL) are the only disease for which four histone deacetylase (HDAC) inhibitors have been approved globally as single agents. Although it is not clear why the PTCL exhibit such a vulnerability to these drugs, understanding the biological basis for this activity is essential.
Ariana Sabzevari   +7 more
wiley   +1 more source

SMAdd-seq: probing chromatin accessibility with small molecule DNA intercalation and nanopore sequencing. [PDF]

open access: yesNucleic Acids Res
Bai G   +10 more
europepmc   +1 more source

Selective Anchoring of TFIID to Nucleosomes by Trimethylation of Histone H3 Lysine 4

open access: yesCell, 2007
M. Vermeulen   +9 more
semanticscholar   +1 more source

HR‐MS Analysis of the Covalent Binding of Edaravone to 5‐Formylpyrimidine Bases and a DNA Oligonucleotide Containing a 5‐Formylcytidine Residue

open access: yesRapid Communications in Mass Spectrometry, Volume 39, Issue 14, 30 July 2025.
ABSTRACT Rationale Edaravone (EDA) is a radical scavenger and an antioxidant drug approved to treat amyotrophic lateral sclerosis and used as a research tool to explore treatment of neurodegenerative diseases and cancers. It is also a reactive agent, known as PMP (1‐phenyl‐3‐methyl‐5‐pyrazolone), used for the analysis of polysaccharides composition ...
Romain Regnault   +5 more
wiley   +1 more source

Force transmission through the inner kinetochore is enhanced by centromeric DNA sequences. [PDF]

open access: yesElife
Miedlar E   +9 more
europepmc   +1 more source

MeCP2 requires interactions with nucleosome linker DNA to read chromatin DNA methylation

open access: yes
Watson JA   +9 more
europepmc   +1 more source

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