Results 181 to 190 of about 2,047,681 (342)

Machine Learning‐Enabled Polymer Discovery for Enhanced Pulmonary siRNA Delivery

Advanced Functional Materials, EarlyView.
This study provides an efficient approach to train a machine learning model by merging heterogeneous literature data to predict suitable polymers for siRNA delivery. Without the need for extensive laboratory synthesis, the machine learning enabled a virtual screening and successfully predicted a polymer that is validated for effective gene silencing in
Felix Sieber‐Schäfer, Min Jiang, Adrian Kromer, Anny Nguyen, Müge Molbay, Simone Pinto Carneiro, David Jürgens, Gerald Burgstaller, Bastian Popper, Benjamin Winkeljann, Olivia Monika Merkel   +10 more
wiley   +1 more source

Visualizing DNA polymerase ι catalyze Hoogsteen-directed DNA synthesis. [PDF]

Nat Commun
Frevert Z, Reusch DT, Gildenberg MS, Jordan SM, Ryan BJ, Freudenthal BD, Washington MT.   +6 more
europepmc   +1 more source

ON THE REQUIREMENT FOR DIPHOSPHOPYRIDINE NUCLEOTIDE IN THE AEROBIC METABOLISM OF PYRUVATE BY BRAIN TISSUE

, 1949
Joseph Larner, Bernard J. Jandorf, William H. Summerson   +2 more
openalex   +1 more source

Pathways of Oxidation in Cell-free Potato Fractions. II. Properties of the Soluble Pyridine Nucleotide Oxidase System. [PDF]

, 1958
David P. Hackett
openalex   +1 more source

Synthetic Strategy for mRNA Encapsulation and Gene Delivery with Nanoscale Metal‐Organic Frameworks

Advanced Functional Materials, EarlyView.
This research utilizes the ZIF‐8 for the encapsulation and intracellular delivery of nucleic acids, specifically mRNA, for applications in gene delivery. Integrating PEI addresses the issue of mRNA leakage from ZIF‐8, resulting in the delivery and expression of green fluorescent protein (GFP) in vitro and firefly luciferase in vivo.
Harrison Douglas Lawson, Huy Hoang Nguyen, Keng‐Jung Lee, Nattarat Wongsuwan, Ayesha Tupe, Mengrou Lu, Mariah Lynn Arral, Anne Behre, Zihan Ling, Kathryn Ann Whitehead, Adam Walter Feinberg, Xi Ren, Si‐Yang Zheng   +12 more
wiley   +1 more source

Correction: A full-length S1 gene sequencing of a novel emerged GI-19 and GI-23 lineages of Infectious bronchitis virus currently circulating in chicken flocks in upper Egypt reveals marked genetic diversity and recombination events. [PDF]

Virol J
Shosha E, Abdelnaser S, Zanaty AM.
europepmc   +1 more source

ISOLATION OF THE RICKETTSIAL INHIBITOR FROM AUTOCLAVED DIPHOSPHOPYRIDINE NUCLEOTIDE

, 1954
Sheldon Rosenberg, Marianna R. Bovarnick
openalex   +1 more source

Quantum Requirement for Phosphopyridine Nucleotide Reduction in Photosynthesis. [PDF]

, 1959
L.N.M. Duysens, J. Amesz
openalex   +1 more source

Antibody‐Programmable Bimetallic Nanozymes for Transcriptional Blockade Therapy in HER2/ER‐Positive Breast Cancer

Advanced Functional Materials, EarlyView.
Zr‐Fe MOF@Ribociclib@Herceptin (ZFRH) efficiently targets/kills Human Epidermal Growth Factor Receptor 2/Estrogen Receptor‐positive (HER2/ER+) breast cancer cells. It combats tumors by: 1) Elevating ROS, altering redox balance; 2) Inhibiting transcription; 3) Inducing pyroptosis.
Hongkun Miao, Tong Ye, Mingjiang Liu, Jingchao Gao, Lian Tan, Qian Dong, Qingbo Lv, Qianqian Ye, Yu Wang   +8 more
wiley   +1 more source

A Histochemical Method for the Demonstration of Diphosphopyridine Nucleotide Diaphorase

, 1958
Marvin M. Nachlas, Donald G. Walker, Arnold M. Seligman   +2 more
openalex   +1 more source