Results 251 to 260 of about 1,684,114 (372)

FUS Selectively Facilitates circRNAs Packing into Small Extracellular Vesicles within Hypoxia Neuron

open access: yesAdvanced Science, EarlyView.
This study aimed to unravel the role of FUS in the loading of functional circRNAs into neuronal sEVs under hypoxic conditions, which involves their aggregations in SGs and specific interaction between the FUS Zf_RanBP domain to regulate circRNA sorting in sEVs.
Jiankun Zang   +14 more
wiley   +1 more source

Development of a cost-effective high-throughput mid-density 5K genotyping assay for germplasm characterization and breeding in groundnut. [PDF]

open access: yesPlant Genome
Pandey MK   +19 more
europepmc   +1 more source

PHOTOSYNTHETIC PYRIDINE NUCLEOTIDE REDUCTASE

open access: hybrid, 1958
Anthony San Pietro, Helga M. Lang
openalex   +1 more source

Deciphering the Transcription Factor Landscape in Prostate Cancer Progression: A Novel Approach to Understand NE Transdifferentiation

open access: yesAdvanced Science, EarlyView.
The study deciphers the landscapes of lineage‐related transcription factors in prostatic adenocarcinoma and neuroendocrine prostate cancer using an innovative approach. These findings, validated across cohorts, highlight TFs' roles in cell development and offer novel therapeutic targets.
Yu Wang   +20 more
wiley   +1 more source

PYRIDINE NUCLEOTIDE TRANSHYDROGENASE

open access: hybrid, 1952
Nathan O. Kaplan   +2 more
openalex   +1 more source

Shrimp Virus Regulates ROS Dynamics via the Nrf2 Pathway to Facilitate Viral Replication

open access: yesAdvanced Science, EarlyView.
Viruses manipulate host ROS as a strategy to achieve successful infection. WSSV exploits Nrf2 pathway to maintain ROS homeostasis and establishes a positive feedback loop to facilitate WSSV replication. Wsv220 competitively binds to Keap1 to activate Nrf2. Nrf2 up‐regulates LvG6PDH to produce more NADPH and GSH to eliminate excessive ROS.
Honghui He   +6 more
wiley   +1 more source

GRP78 Nanobody‐Directed Immunotoxin Activates Innate Immunity Through STING Pathway to Synergize Tumor Immunotherapy

open access: yesAdvanced Science, EarlyView.
A GRP78 nanobody‐directed immunotoxin suppresses cancer progression and metastasis by enhancing antitumor immunity via STING pathway activation, offering a pan‐cancer‐targeted approach and immunotherapy combination strategy. Abstract The lack of targetable antigens poses a significant challenge in developing effective cancer‐targeted therapies.
Huifang Wang   +16 more
wiley   +1 more source

Editorial: Targeting nucleotide metabolism for enhancing antitumor immunity

open access: yesFrontiers in Immunology
Jun Wu   +7 more
doaj   +1 more source

Detection and characterization of bovine coronavirus and rotavirus in calves in Ethiopia. [PDF]

open access: yesBMC Vet Res
Redda YT   +6 more
europepmc   +1 more source

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