Results 271 to 280 of about 1,867,455 (347)

Within-host genetic diversity of pneumococcal serotype 3 during one-year prolonged carriage in a healthy adult. [PDF]

Nat Commun
Sibale LL, Lo SW, Kalata N, Nyazika TK, Mitole N, Dyster V, Kusakala A, Khwiya M, Sagawa G, Phiri JA, Kalizang'oma A, Swarthout TD, Malisita K, Kamng'ona AW, Heyderman RS, Bentley SD, Kwambana-Adams BA, Chaguza C, Jambo KC.   +18 more
europepmc   +1 more source

Antibody‐Functionalized DNA Hydrogels Recognize and Isolate Living Tumor Cells

Advanced Materials Interfaces, EarlyView.
We present a novel strategy using DNA Y‐motif nanostar hydrogels and DNA‐functionalized antibodies for precise live‐cell manipulation. Target cells are labeled with DNA sticky ends that hybridize with DNA Y‐motifs, enabling their incorporation and capture within the hydrogel during self‐assembly.
Laura Bourdon, Audrey Cochard, Yannick Tauran, Yoshinobu Sugitani, Yusuke Sato, Masahiro Takinoue, Hiroyuki Fujita, Teruo Fujii, Soo Hyeon Kim, Anthony J. Genot   +9 more
wiley   +1 more source

Identification and genetic evolutionary analysis of goose circovirus in Shandong and neighboring provinces in China in 2024. [PDF]

Poult Sci
Yang X, Wang Y, Wu P, Zhu T, Zhang S, Yang X, Meng X, Jiang Z, Lu Y, Ning Z, Wu X, Song X, Jiang S, Wei L.   +13 more
europepmc   +1 more source

Dual‐Functional Ingestible Passive Capsules for High‐Throughput Intestinal Sampling with Sealed Containment and Targeted Drug Delivery

Advanced Robotics Research, EarlyView.
To address challenges in high‐throughput intestinal sampling with sealed containment and target drug delivery, we developed a dual‐functional ingestible passive capsule with a dual‐triggered control system based on pH‐response and mechanical actuation.
Libing Huang, Houyu Ling, Xizong Chen, Yufei Duan, Yu Liu, Shuntian Cai, Yandan Ren, Wenlong Li, Lei Ren, Miao Wang   +9 more
wiley   +1 more source

Metagenomic Sequencing of Maize Reveals Abundant Genomic RNA of a Comovirus, a Genus Previously Known to Infect Only Dicots. [PDF]

Plant Pathol J
Ilbağı H, Kanakala S, Masonbrink R, Lozier Z, Miller WA.   +4 more
europepmc   +1 more source

Glucose Deprivation‐Induced Disulfidptosis via the SLC7A11‐INF2 Axis: Pan‐Cancer Prognostic Exploration and Therapeutic Validation

Advanced Science, EarlyView.
Glucose deprivation or GLUT1 inhibition induces disulfidptosis in SLC7A11high ovarian cancer cells by promoting cystine accumulation, NADPH/ATP depletion, and F‐actin disulfide formation. SLC7A11 interacts with INF2 to further increase H₂O₂ levels and impair mitochondrial fission, suppressing cell migration. Targeting the SLC7A11–INF2 axis represents a
Zhenyu Song, Qiuming Yao, Lina Huang, Dan Cui, Jun Xie, Leilei Wu, Jianfeng Huang, Bo Zhai, Dan Liu, Xiao Xu   +9 more
wiley   +1 more source

A divergent cyclic nucleotide binding protein promotes Plasmodium ookinete infection of the mosquito. [PDF]

PLoS Pathog
Kwecka D, Wang Z, Eigminas E, Liu L, Regan JC, Kim C, Philip N.   +6 more
europepmc   +1 more source

XBP1s Mediates Cross‐resistance to Combination Treatment of CDK4/6 Inhibitors plus Endocrine Therapy in Breast Cancer

Advanced Science, EarlyView.
Elevated spliced form of X‐box–binding protein 1 (XBP1) correlates with unfavorable responses to endocrine therapy plus CDK4/6 inhibitors in HR+/HER2− advanced breast cancer. XBP1s facilitates cell proliferation and G1/S transition by transcriptionally activating SND1, thereby activating the E2F1 pathway.
Yuting Sang, Shiyang Liu, Xujie Zhou, Weiru Chi, Min Xiong, Ming Chen, Hengyu Ren, Douwaner Liu, Liyi Zhang, Jingyan Xue, Yayun Chi, Jiong Wu   +11 more
wiley   +1 more source

Phylogenetics and selective pressure analysis of human papillomavirus types 31 and 33 variants in Eastern China. [PDF]

BMC Infect Dis
Wang Y, Qu W, Zhou Q, Gong Y, Wang Y, Chen F, Mo J, Lin L, Bi T, Shi W, Zhang F, Wu Z, Sun Y, Liu X, He N, Li Y, Xu C.   +16 more
europepmc   +1 more source

Excessive DNA Double‐Strand Breaks–Associated 3D Genome Reorganization Contributes to Neural Tube Defects with Folate Deficiency

Advanced Science, EarlyView.
Neural tube defects (NTDs) are among the most common congenital malformations. However, the underlying etiology and mechanism remain elusive. Here, the role of DNA double‐strand breaks (DSBs) in 3D genome organization within the NTDs with folate deficiency is reported.
Ting Zhang, Lin Lin, Jianting Li, Caihua Li, Shengjun Liang, Xuemei Bai, Fang Wang, Yihua Bao, Dan Guo, Xiaochen Bo, Hao Li, Hebing Chen, Qiu Xie   +12 more
wiley   +1 more source