Results 281 to 290 of about 1,867,455 (347)

Beyond sequence: A physics-informed machine learning framework for predicting DNA mutations. [PDF]

Comput Struct Biotechnol J
Suárez-Villagrán M, Mitsakos N, Miller JH.   +2 more
europepmc   +1 more source

An Allele of Glutamate Formiminotransferase Triggers 5‐Methyl‐Tetrahydrofolate‐to‐MeFox Conversion and Facilitates Folate Biofortification in Maize

Advanced Science, EarlyView.
This work demonstrates the distinct roles of the glutamate formiminotransferase (GFT) enzyme in plants. The GFT triggers the conversion of 5‐methyl‐tetrahydrofolate to MeFox in plants, a process distinct from its role as a formiminotransferase in mammals.
Tong Lian, Wenzhu Guo, Yanjing Wang, Weiwei Wen, Weixuan Wang, Ling Jiang, Qiuju Liang, Ji'an Liu, Haijun Liu, Yuan Xue, Lixu Pan, Qiaoquan Liu, Ping Yin, Delin Zhang, Jianbing Yan, Chunyi Zhang   +15 more
wiley   +1 more source

Molecular characterization of Coxsackievirus A2 isolated from hand, foot and mouth disease in eastern China. [PDF]

Microb Genom
Chen L, Zhao G, Wang H, He Z, Chen N, Guo W.   +5 more
europepmc   +1 more source

Activation of Lysosomal Retrograde Transport Triggers TPC1‐IP3R1 Ca2+ Crosstalk at Lysosome‐ER MCSs Leading to Lethal Depleting of ER Calcium

Advanced Science, EarlyView.
The flavonoid compound LW‐213 exerts its antitumor effects through a novel mechanism involving lysosomal‐ER calcium regulation. Specifically, LW‐213 binds to LIMP2, which induces perinuclear clustering of lysosomes and facilitates calcium‐mediated lysosome‐ER interactions.
Meng‐yuan Zhu, Yong‐jian Guo, Yu‐qi Zhu, Hong‐zheng Wang, Hai‐di Wang, Hong‐yu Chen, Yue‐xin Jiang, Hui Li, Hui Hui   +8 more
wiley   +1 more source

Surveillance of tick-borne viruses in the border regions of the Tumen River Basin: Co-circulation in ticks and livestock. [PDF]

PLoS Negl Trop Dis
Liu Z, Ji S, Chang Q, Wang J, Galon EM, Xu Y, Yin G, Li J, Gao X, Tian W, Han Z, Li C, Xu Z, Du R, Xue S.   +14 more
europepmc   +1 more source

Homeostasis of Gut Microbiota Protects against Susceptibility to Fungal Pneumonia

Advanced Science, EarlyView.
Fungal pneumonia induces inflammation, shown by heightened IL‐6, IL‐1β, TNF‐α levels and a growth in Staphylococcus in the alveolar flora. The gut microbiota, acting through the gut‐lung axis via blood, impacts fungal pneumonia susceptibility by altering lung metabolism and inflammatory responses.
Jian Ji, Yongli Ye, Jiadi Sun, Lina Sheng, Jinyou Li, Jin Yang, Bing Wu, Yuting Wang, Xingxing Gao, Liang Luo, Jianfeng Ping, Yinzhi Zhang, Xiulan Sun   +12 more
wiley   +1 more source

Genomic insights into Yanbian cattle: Breed-specific selective sweeps identified by whole-genome sequencing. [PDF]

PLoS One
Baek J, Yan CL, Gao Q, Son S, Lee HK, Shin D, Yan CG.   +6 more
europepmc   +1 more source

Transcriptome‐Wide Association Uncovers LncRNAs Controlling Seed Weight in Soybean

Advanced Science, EarlyView.
This study employs transcriptome‐wide association studies (TWAS) to identify 201 long non‐coding RNAs (lncRNAs) associated with seed weight. Expression quantitative trait locus (eQTL) analysis reveals dynamic and static regulatory variants controlling lncRNA expression across development.
Xiang Wang, Xinyu Jiang, Xiaobo Yuan, Zhipeng Zhou, Zhenwei Zhao, Longfei Wang, Wu Jiao, Wenxue Ye, Qingxin Song   +8 more
wiley   +1 more source

Molecular Epidemiology, Lineage Evolutionary Dynamics, and Antigenic Variation Analysis of Type II PRRSV in China During 2024-2025. [PDF]

Transbound Emerg Dis
Zhu D, Liu G, Li H, Li F, Xu X, Fu Y, Chen P, Zhang G, Sun Y.   +8 more
europepmc   +1 more source