Results 81 to 90 of about 280,333 (306)
Micro satellite mapping of plant genomes [PDF]
Selekcija i Semenarstvo, 2001 Micro satellites are DNA markers, based on the repeated nucleotide sequences number polymorphism. They belong to a group of PCR markers and are mainly used as an addition to other types of markers.
Prodanović Slaven +2 more
doaj
FEBS Letters, EarlyView.An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley +1 more source
Distribution of nucleotide quality according to mapping status.
, 2016 The nucleotide quality scores were analyzed according to mapping status. In the mapped reads, there was no significant difference between the distributions of the 2 types of sample.
Ryong Nam Kim (834524) +7 more
core +1 more source
Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis
FEBS Letters, EarlyView.Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee +7 more
wiley +1 more source
Multilocus patterns of nucleotide variability and the demographic and selection history of drosophila melanogaster populations [PDF]
, 2005 Uncertainty about the demographic history of populations can hamper genome-wide scans for selection based on population genetic models. To obtain a portrait of the effects of demographic history on genome variability patterns in Drosophila melanogaster ...
Haddrill, Penelope R +7 more
core +1 more source
High throughput ANI analysis of 90K prokaryotic genomes reveals clear species boundaries
Nature Communications, 2018 Average Nucleotide Identity (ANI) is a robust and useful measure to gauge genetic relatedness between two genomes. Here, the authors develop FastANI, a method to compute ANI using alignment-free approximate sequence mapping, and show 95% ANI is an ...
Chirag Jain +4 more
doaj +1 more source
FEBS Letters, EarlyView.CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens +8 more
wiley +1 more source
Interaction Between Kb and Q4 Gene Sequences Generates the Kbm6 Mutation [PDF]
, 1986 Genetic interaction as a mechanism for the generation of mutations is suggested by recurrent, multiple nucleotide substitutions that are identical to nucleotide sequences elsewhere in the genome.
Pease, Larry R. +7 more
core +1 more source
Single nucleotide polymorphisms and disease gene mapping.
Arthritis research, 2002 Single nucleotide polymorphisms are the most important and basic form of variation in the genome, and they are responsible for genetic effects that produce susceptibility to most autoimmune diseases. The rapid development of databases containing very large numbers of single nucleotide polymorphisms, and the characterization of haplotypes and patterns ...
openaire +2 more sources
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source