Results 81 to 90 of about 1,708,901 (308)

Singapore 1:25,000 road map [cartographic material] /

open access: yes, 1980
Ed. 3 SMU. Shows selected buildings, points of interest, and schools.; Base information, aerial photography dated Jan. 1974, Aug. 1979 and partial ground verification up to Jan. 1980.; "R.S.O. metric grid."; Some sheets include insets.; Includes lists of
Singapore. Ministry of Defence. Mapping Unit.
core  

Finding novel vulnerabilities of hypomorphic BRCA1 alleles

open access: yesMolecular Oncology, EarlyView.
Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder   +10 more
wiley   +1 more source

G-MAPSEQ – a new method for mapping reads to a reference genome

open access: yesFoundations of Computing and Decision Sciences, 2016
The problem of reads mapping to a reference genome is one of the most essential problems in modern computational biology. The most popular algorithms used to solve this problem are based on the Burrows-Wheeler transform and the FM-index.
Wojciechowski Pawel   +4 more
doaj   +1 more source

Identification of Single Nucleotide Polymorphisms and analysis of Linkage Disequilibrium in sunflower elite inbred lines using the candidate gene approach

open access: yesBMC Plant Biology, 2008
Background Association analysis is a powerful tool to identify gene loci that may contribute to phenotypic variation. This includes the estimation of nucleotide diversity, the assessment of linkage disequilibrium structure (LD) and the evaluation of ...
Heinz Ruth A   +4 more
doaj   +1 more source

Urandangi, Queensland [cartographic material] /

open access: yes, 1951
1st ed. Topographic map of Urandangi region, Queensland, showing classes of roads, railway and telephone lines, fences, state boundries, watercourses and dams, windpumps, and bore, tank and well classifictions. Relief shown by hachures and spot heights.;
Australia. National Mapping Section.
core  

MITF maintains genome stability in nonmelanocyte lineages

open access: yesMolecular Oncology, EarlyView.
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir   +13 more
wiley   +1 more source

Analysis of whole genome sequence of strain "0" of avian infectious laryngotracheitis virus

open access: yesВетеринария сегодня, 2018
Data on identification and analysis of whole genome nucleotide sequence of strain «O» of avian infectious laryngotracheitis virus are demonstrated.
A. A. Kozlov   +4 more
doaj  

Reference Genome Anchoring of High-Density Markers for Association Mapping and Genomic Prediction in European Winter Wheat

open access: yesFrontiers in Plant Science, 2019
In this study, we anchored genotyping-by-sequencing data to the International Wheat Genome Sequencing Consortium Reference Sequence v1.0 assembly to generate over 40,000 high quality single nucleotide polymorphism markers on a panel of 376 elite European
Olufunmilayo Ladejobi   +7 more
doaj   +1 more source

Avon Downs, Northern Territory [cartographic material] /

open access: yes, 1952
1st ed. Topographic map of Avon Downs region, Northern Territory, showing classes of roads, railway and telephone lines, fences, state boundries, watercourses and dams, windpumps, and bore, tank and well classifictions.
Australia. National Mapping Section.
core  

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola   +11 more
wiley   +1 more source

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