Functional and mechanistic aspects of endogenous RNAi in C. elegans
RNAi is widely used as a genetic tool in a range of model organisms, however still relatively little is known about the endogenous functions of RNAi. In this thesis we have studied several aspects of the endogenous role of RNAi in order to enhance our ...
Wolfswinkel van, J.C. +4 more
core
Dysregulation of a nucleotidyltransferase induces division and surface glycan defects in <i>Escherichia coli</i> by altering related metabolite levels. [PDF]
Zheng MC +6 more
europepmc +1 more source
Regulation of RNA stability by terminal nucleotidyltransferases [PDF]
The dysregulation of RNAs has global effects on all cellular pathways. The regulation of RNA metabolism is thus tightly controlled. Terminal RNA nucleotidyltransferases (TENTs) regulate RNA stability and activity through the addition of non-templated nucleotides to the 3′-end.
openaire
<i>Pseudomonas aeruginosa</i> tRNA nucleotidyltransferase Cca controls resistance and tolerance to aminoglycoside antibiotics by regulating the MexXY multidrug efflux pump. [PDF]
Shen C +8 more
europepmc +1 more source
Proteomic Insights into Antimicrobial Resistance Mechanisms in Human-Associated Bacterial Pathogens. [PDF]
Babele P +4 more
europepmc +1 more source
Discovery and characterization of a novel chromosomally encoded aminoglycoside <i>O</i>-nucleotidyltransferase gene, designated <i>ant(9)-Ie</i>, in a strain of <i>Providencia</i>. [PDF]
Huang L +14 more
europepmc +1 more source
The post-reactive structures of <i>Leishmania major</i> UDP-sugar pyrophosphorylase provide insights into the product release mechanism. [PDF]
Prakash O +4 more
europepmc +1 more source
Bacterial 2',3'-cGAMP activates a SAVED effector to form membrane-disrupting filaments and restrict phage replication. [PDF]
Tak U +5 more
europepmc +1 more source
Temporal dynamics of the resistome in gilts raised in an organic operation in which semen used for artificial insemination is the primary source of antimicrobial exposure. [PDF]
Brito LFC +5 more
europepmc +1 more source
cGAS/STING-mediated γδ T cell recruitment drives radioresistance: implications for improving radioimmunotherapy outcomes. [PDF]
Braman BC, Raleigh DR.
europepmc +1 more source

