Results 81 to 90 of about 1,773 (158)

Identification of the Novel Lincosamide Resistance Gene lnu(E) Truncated by ISEnfa5-cfr-ISEnfa5 Insertion in Streptococcus suis: De Novo Synthesis and Confirmation of Functional Activity in Staphylococcus aureus [PDF]

, 2013
The novel lincosamide resistance gene lnu(E), truncated by insertion of an ISEnfa5-cfr-ISEnfa5 segment, was identified in Streptococcus suis.
Schwarz, Stefan, Shen, J., Wendlandt, Sarah, Zhao, Q., Wu, C., Li, H., Wang, Y.   +6 more
core   +1 more source

Network Pharmacology‐Based Identification of Potential Targets and Mechanisms of Isoginkgetin in Gastric Cancer

BioMed Research International, Volume 2026, Issue 1, 2026.
Background Isoginkgetin (ISO) is a natural flavonoid with potential anticancer effects. However, the anticancer mechanisms of ISO in gastric cancer remain insufficiently explored. Methods Network pharmacology, TCGA data analysis, and molecular docking were employed to identify potential ISO targets and their involvement in gastric cancer ...
Linen Li, Huiling Zhu, Kun Cao, Hao Chen, Poorani Gurumallesh Prabu   +4 more
wiley   +1 more source

DNA nucleotidyltransferases in cells infected with Shope Fibroma virus [PDF]

, 1968
This document only includes an excerpt of the corresponding thesis or dissertation. To request a digital scan of the full text, please contact the Ruth Lilly Medical Library's Interlibrary Loan Department (rlmlill@iu.edu)
Chang, Lucy Ming Shih
core   +1 more source

Clinical Efficacy of Traditional Chinese Medicine Chaihu‐Guizhi‐Ganjiang Decoction Combined With Danggui‐Shaoyao‐San for the Treatment of Oligomenorrhea: A Prospective, Open‐Label Clinical Study

International Journal of Clinical Practice, Volume 2026, Issue 1, 2026.
Objective To assess the efficacy and safety of Chaihu‐Guizhi‐Ganjiang decoction (CGGJD) combined with Danggui‐Shaoyao‐San (DS) in oligomenorrhea treatment. Methods In this prospective open‐label trial, 35 oligomenorrhea patients (30–40 years) received CGGJD‐DS for 3 months, followed by a 2‐month follow‐up.
Mei Yu, Gui-Yan Liu, Wen-Xuan Zhou, Zhao-Hua Liu, Lian-Tao Li, Jin Chai   +5 more
wiley   +1 more source

Characterization of Giant Myoviridae With Therapeutic Potential Against Grouper Pathogen, Vibrio alginolyticus

International Journal of Microbiology, Volume 2026, Issue 1, 2026.
Background Vibrio alginolyticus is a gram‐negative bacterium responsible for mass mortality in cultured groupers, leading to significant economic losses in the aquaculture industry. Although preventive measures such as chemical treatments, antibiotics, and pesticides have been employed, these methods have been reported to be toxic to the environment ...
Mohammad Tamrin Mohamad Lal, Rafidah Othman, Elliecpearl Jasca Joning, Gilbert Ringgit, Nor Azman Kasan, Motohiko Sano, Ibnu Bangkit Bioshina Suryadi, Attabik Mukhamad Amrillah, Julian Ransangan, Esha Saini   +9 more
wiley   +1 more source

Surprising Bacterial Nucleotidyltransferase Selectivity in the Conversion of Carbaglucose-1-phosphate

, 2016
The drive to understand the molecular determinants of carbohydrate binding as well as the search for more chemically and biochemically stable sugar derivatives and carbohydrate-based therapeutics has led to the synthesis of a variety of analogues that ...
Corbin J. Zea (2186041), Kwang-Seuk Ko (1572745), Nicola L. Pohl (2295247)   +2 more
core   +1 more source

Two complementing in vivo selection systems based on CCA-trimming exonucleases as a tool to monitor, select and evaluate enzymatic features of tRNA nucleotidyltransferases

RNA Biology
tRNA nucleotidyltransferase represents a ubiquitous and essential activity that adds the indispensable CCA triplet to the 3’-end of tRNAs. To fulfill this function, the enzyme contains a set of highly conserved motifs whose coordinated interplay is ...
Karolin Wellner, Josefine Gnauck, Dorian Bernier, Stephan H. Bernhart, Heike Betat, Mario Mörl   +5 more
doaj   +1 more source

Bacterial cGAS-like enzymes synthesize diverse nucleotide signals

Nature, 2019
Cyclic dinucleotides (CDNs) have central roles in bacterial homeostasis and virulence by acting as nucleotide second messengers. Bacterial CDNs also elicit immune responses during infection when they are detected by pattern-recognition receptors in ...
A. T. Whiteley, J. Eaglesham, C. C. de Oliveira Mann, B. R. Morehouse, B. Lowey, E. A. Nieminen, Olga Danilchanka, D. S. King, Amy S. Y. Lee, J. Mekalanos, P. Kranzusch   +10 more
semanticscholar   +1 more source

Inhibition of reverse transcriptases by seminalplasmin [PDF]

, 1983
Seminalplasmin, an antibacterial protein present in bovine seminal plasma, is shown to be a potent inhibitor of reverse transcriptases (RNA-dependent DNA nucleotidyltransferases).
Reddy, E. P., Reddy, E. S., Das, M. R., Bhargava, P. M.   +3 more
core   +2 more sources

A new yeast poly(A) polymerase complex involved in RNA quality control [PDF]

, 2005
Eukaryotic cells contain several unconventional poly(A) polymerases in addition to the canonical enzymes responsible for the synthesis of poly(A) tails of nuclear messenger RNA precursors.
Sabine Dettwiler (27038), Arno Friedlein (27039), Keller Walter, Stepánka Vanácová, Vanacova, S., Blank Diana, Martin Georges, Gérard Keith, Keller, W., Sabine Dettwiler, Jeannette Wolf (27035), Langen, H., Keith, G., Diana Blank (27037), Vanˇácˇová Sˇteˇpánka, Vanácová Stepánka, Georges Martin, Hanno Langen, Diana Blank, Hanno Langen (27040), Gérard Keith (27041), Keith Gérard, Walter Keller (27042), Wolf, J., Jeannette Wolf, Blank, D., Arno Friedlein, Wolf Jeannette, Štěpánka Vaňáčová (27034), Walter Keller, Friedlein, A., Langen Hanno, Friedlein Arno, Dettwiler, S., Dettwiler Sabine, Georges Martin (27036), Martin, G.   +36 more
core   +1 more source