Results 1 to 10 of about 4,680 (126)

RNA Tailing by Nucleotidyltransferases in Plants: Mechanisms, Functions, and Biological Significance [PDF]

open access: yesPlants
RNA tailing, the non-templated addition of nucleotides to RNA 3′ ends, is a conserved post-transcriptional modification that plays a critical role in regulating RNA metabolism.
Xintong Xu   +6 more
doaj   +6 more sources

A Phylogeny of Bacterial RNA Nucleotidyltransferases: Bacillus halodurans Contains Two tRNA Nucleotidyltransferases [PDF]

open access: yesJournal of Bacteriology, 2005
ABSTRACT We have analyzed the distribution of RNA nucleotidyltransferases from the family that includes poly(A) polymerases (PAP) and tRNA nucleotidyltransferases (TNT) in 43 bacterial species. Genes of several bacterial species encode only one member of the nucleotidyltransferase superfamily (NTSF), and if that protein functions
Patricia Bralley, George H Jones
exaly   +5 more sources

Molecular mechanisms of template-independent RNA polymerization by tRNA nucleotidyltransferases [PDF]

open access: yesFrontiers in Genetics, 2014
The universal 3'-terminal CCA sequence of tRNA is built and/or synthesized by the CCA-adding enzyme, CTP:(ATP) tRNA nucleotidyltransferase. This RNA polymerase has no nucleic acid template, but faithfully synthesizes the defined CCA sequence on the 3 ...
Kozo eTomita, Seisueke eYamashita
doaj   +5 more sources

Recognition of the tRNA-like structure in tobacco mosaic viral RNA by ATP/CTP:tRNA nucleotidyltransferases from Escherichia coli and Saccharomyces cerevisiae.

open access: yesJournal of Biological Chemistry, 1990
The 3'-terminal tRNA-like structure of the tobacco mosaic virus RNA interacts with ATP/CTP:tRNA nucleotidyltransferases from Escherichia coli or yeast in much the same manner as do tRNAs. Primary sites of interaction cluster near the 3' end and in the loop proposed to be analogous to the psi-loop of a tRNA.
D L Thurlow
exaly   +3 more sources

The Battle for Survival: The Role of RNA Non-Canonical Tails in the Virus–Host Interaction

open access: yesMetabolites, 2023
Terminal nucleotidyltransferases (TENTs) could generate a ‘mixed tail’ or ‘U-rich tail’ consisting of different nucleotides at the 3′ end of RNA by non-templated nucleotide addition to protect or degrade cellular messenger RNA.
Xianghui Wen, Ahsan Irshad, Hua Jin
doaj   +1 more source

Promiscuous splicing-derived hairpins are dominant substrates of tailing-mediated defense of miRNA biogenesis in mammals

open access: yesCell Reports, 2023
Summary: Canonical microRNA (miRNA) hairpins are processed by the RNase III enzymes Drosha and Dicer into ∼22 nt RNAs loaded into an Argonaute (Ago) effector.
Seungjae Lee   +10 more
doaj   +1 more source

TYMV RNA As a substrate of the tRNA nucleotidyltransferase [PDF]

open access: yesFEBS Letters, 1970
It has been recently shown that in the presence of partly purified enzyme preparations from Escherichia coli and ATP. lhe RNA (M.W. = 2 × 106) of Turnip Yellow Mosaic Virus (TYMV) reacts with valine forming an ester bond analogous to that existing in aminoacyltRNA: lhe valine estcrifies the., -terminal adenosine ofTYMV RNA II. 21.
Litvak, S., Carré, D.S., Chapeville, F.
openaire   +2 more sources

Functions and mechanisms of RNA tailing by metazoan terminal nucleotidyltransferases [PDF]

open access: yesWIREs RNA, 2020
AbstractTermini often determine the fate of RNA molecules. In recent years, 3′ ends of almost all classes of RNA species have been shown to acquire nontemplated nucleotides that are added by terminal nucleotidyltransferases (TENTs). The best‐described role of 3′ tailing is the bulk polyadenylation of messenger RNAs in the cell nucleus that is catalyzed
Liudkovska, Vladyslava   +1 more
openaire   +2 more sources

The influence of spermidine on the reaction of RNA nucleotidyltransferase

open access: yesBiochimica et Biophysica Acta (BBA) - Nucleic Acids and Protein Synthesis, 1968
Abstract 1. 1. RNA synthesis, catalyzed by RNA nucleotidyltransferase ( Escherichia coli B) and directed by native, double-stranded DNA, is significantly increased by spermidine. 2. 2. By use of doubly labeled ATP ([8- 14 C]- and [γ- 32 P]-) and by zone centrifugation, we could show that, in the presence of spermidine, more RNA chains are ...
Petersen, E. E., Kroeger, H., Hagen, U.
openaire   +5 more sources

RNA minihelices as model substrates for ATP/CTP:tRNA nucleotidyltransferase [PDF]

open access: yesBiochemical Journal, 1997
Twenty-one RNA minihelices, resembling the coaxially stacked acceptor- /T-stems and T-loop found along the top of a tRNA's three-dimensional structure, were synthesized and used as substrates for ATP/CTP:tRNA nucleotidyltransferases from Escherichia coli and Saccharomyces cerevisiae.
Z, Li, Y, Sun, D L, Thurlow
openaire   +2 more sources

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