Results 41 to 50 of about 5,405 (175)

Turnip Yellow Mosaic Virus RNA as a Substrate of the Transfer RNA Nucleotidyltransferase II. Incorporation of Cytidine 5′-Monophosphate and Determination of a Short Nucleotide Sequence at the 3′ End of the RNA [PDF]

Journal of Virology, 1973
Turnip yellow mosaic virus (TYMV) RNA treated with snake venom phosphodiesterase accepts cytidine 5′-monophosphate and adenosine 5′-monophosphate (AMP) when it is incubated in the presence of cytidine 5′-triphosphate (CTP), adenosine 5′-triphosphate, and Escherichia coli transfer RNA nucleotidyltransferase ...
S, Litvak, L, Tarrago-Litvak, F, Chapeville   +2 more
openaire   +2 more sources

Antimicrobial Effect of Spices and Their Phytochemicals: A Novel Approach to Overcoming Antibiotic Resistance

MedComm, Volume 7, Issue 4, April 2026.
This graphical abstract shows the antibacterial potential of phytochemicals from 15 spices, showcasing key compounds, their extraction methods, and mechanisms of action. It highlights membrane disruption, ROS generation, enzyme inhibition, and biofilm prevention as core antibacterial pathways.
Hettiyahandi Binodh De Silva, Yanqi Dai, Shervanthi Homer‐Vanniasinkam, Mohan Edirisinghe   +3 more
wiley   +1 more source

Inducible auto-phosphorylation regulates a widespread family of nucleotidyltransferase toxins

Nature Communications
Nucleotidyltransferases (NTases) control diverse physiological processes, including RNA modification, DNA replication and repair, and antibiotic resistance.
Tom J. Arrowsmith, Xibing Xu, Shangze Xu, Ben Usher, Peter Stokes, Megan Guest, Agnieszka K. Bronowska, Pierre Genevaux, Tim R. Blower   +8 more
doaj   +1 more source

Biochemical Engineering Perspective on cGAS: From Enzyme Discovery to Potential Industrial Application

ChemBioChem, Volume 27, Issue 5, 13 March 2026.
This review examines the structural and enzymatic properties of cyclic GMP‐AMP synthase, including substrate promiscuity, homologs, and engineered variants. In addition, it evaluates potential expression systems for large‐scale enzyme production and analyzes reaction and purification strategies for the synthesis of cyclic dinucleotides to connect ...
Makram Fataeri, Katrin Rosenthal
wiley   +1 more source

Bacterial resistance to antimicrobial agents and its impact on veterinary and human medicine [PDF]

, 2016
Background Antimicrobial resistance has become a major challenge in veterinary medicine, particularly in the context of bacterial pathogens that play a role in both humans and animals.
Aarestrup, Abedon, Arais, Becker, Bikard, Blondeau, Brackman, Bradford, Brandenburg, Brogden, Burrus, Bush, Bush, Bywater, Chopra, Clinical and Laboratory Standards Institute, Clinical and Laboratory Standards Institute, Clinical and Laboratory Standards Institute, Connell, Couto, Cuny, D'Costa, Damborg, Duijkeren, Ewers, Ewers, Falgenhauer, Feßler, Fischetti, Fuente-Núñez, Giessen, Goh, Grobbel, Grobbel, Groves, Guardabassi, Hall, Harada, Harrison, Hill, Hillier, International Working Group on the Classification of Staphylococcal Cassette Chromosome Elements (IWG-SCC), Kadlec, Kadlec, Kadlec, Kadlec, Kehrenberg, Köck, Laube, Lefebvre, Lindsay, Lloyd, Long, Lyon, Lüthje, Maaland, Maddox, Magiorakos, Mascaretti, McCarthy, McCarthy, McNulty, Michael, Michael, Michael, Moodley, Mueller, Nienhoff, Nobrega, O'Neill, Paterson, Perreten, Poole, Putman, Ramirez, Redgrave, Richter, Riesenberg, Roberts, Roberts, Roberts, Ruiz, Rule, Schaufler, Schmiedel, Schneider, Schuch, Schultz, Schwarz, Schwarz, Schwarz, Schwarz, Schwarz, Schwarz, Schwarz, Schwarz, Schwarz, Schwarz, Scott, Shen, Sing, Soares, Sobral, Thandar, Thomas, Tsonos, van, von, Walther, Wang, Weiß, Wendlandt, Wendlandt, Wendlandt, Wendlandt, Wendlandt, Werckenthin, Westgarth, Westgarth, White, Wu, Zervos, Zhao, Zurek   +123 more
core   +3 more sources

Small Extracellular Vesicles in Gestational Diabetes Mellitus: Current Landscape and Emerging Diagnostic Horizons

Journal of Extracellular Biology, Volume 5, Issue 3, March 2026.
ABSTRACT Gestational diabetes mellitus (GDM) is a common metabolic disorder of pregnancy associated with significant maternal and neonatal morbidity and mortality. Current diagnostic strategies, particularly the oral glucose tolerance test (OGTT), are limited by late detection, variability in diagnostic criteria, and patient burden, highlighting the ...
Mai Ahmed, Dada Oluwaseyi Temilola, Mushi Matjila, Manogari Chetty   +3 more
wiley   +1 more source

6-O-Nucleotidyltransferase: an aminoglycoside-modifying enzyme specific for streptomycin/streptidine [PDF]

, 2016
Aminoglycosides are especially useful for the treatment of hospital-acquired infections. The main problem for the application of these antibiotics is the presence of bacterial resistance enzymes, in particular, nucleotidyltransferases (ANTs).
Bastida, Agatha, García-Junceda, Eduardo, Latorre, Montserrat, Revuelta, Julia   +3 more
core   +1 more source

Histone mRNA is subject to 3’ uridylation and re-adenylation in Aspergillus nidulans [PDF]

, 2021
The role of post‐transcriptional RNA modification is of growing interest. One example is the addition of non‐templated uridine residues to the 3′ end of transcripts.
Bharudin, Izwan, Browne-Marke, Natasha, Caddick, Mark X., Connell, Sean R., Fucini, Paola, Mayans, Olga, Morozov, Igor, Mossanen-Parsi, A, Parisi, Daniele   +8 more
core   +2 more sources

The potato cyst nematode Globodera pallida overcomes major potato resistance through selection on standing variation at a single locus

New Phytologist, Volume 249, Issue 6, Page 3039-3059, March 2026.
Summary Globodera pallida poses a major threat to potato production, with management strategies primarily relying on genetic resistance. However, increasing virulence in field populations across Western Europe raises major concerns for G. pallida control.
Arno S. Schaveling, Dennie M. te Molder, Paul Heeres, Joris J. M. van Steenbrugge, Stefan J. S. van de Ruitenbeek, Casper C. van Schaik, Sven van den Elsen, Geert Smant, Mark G. Sterken   +8 more
wiley   +1 more source

Upstream molecular signaling pathways of p27(Kip1) expression: effects of 4-hydroxytamoxifen, dexamethasone, and retinoic acids [PDF]

, 2010
Background p27(Kip1) is a cyclin-dependent kinase inhibitor that inhibits G1-to-S phase transition of the cell cycle. It is known that a relatively large number of nutritional and chemopreventive anti-cancer agents specifically up-regulate expression of ...
Isao Eto
core   +1 more source