Results 61 to 70 of about 4,731 (160)

Regulation of RNA stability by terminal nucleotidyltransferases [PDF]

open access: yes, 2019
The dysregulation of RNAs has global effects on all cellular pathways. The regulation of RNA metabolism is thus tightly controlled. Terminal RNA nucleotidyltransferases (TENTs) regulate RNA stability and activity through the addition of non-templated nucleotides to the 3′-end.
openaire  

Primase-polymerases are a functionally diverse superfamily of replication and repair enzymes [PDF]

open access: yes, 2015
Until relatively recently, DNA primases were viewed simply as a class of proteins that synthesize short RNA primers requisite for the initiation of DNA replication.
Thomas A Guilliam (16214075)   +7 more
core   +1 more source

Evidence that virion-associated VP1 of avibirnaviruses contains viral RNA sequences

open access: yes
The VP1 encoded by genomic segment B of birnaviruses is generally known to exist as a genome-linked protein (VPg) and as a 'free' polypeptide of 90 kDa in virus particles.

core   +1 more source

Domain movements during CCA-addition: A new function for motif C in the catalytic core of the human tRNA nucleotidyltransferases

open access: yes, 2015
CCA-adding enzymes are highly specific RNA polymerases that synthesize and maintain the sequence CCA at the tRNA 3′-end. This nucleotide triplet is a prerequisite for tRNAs to be aminoacylated and to participate in protein biosynthesis.
Felix G M Ernst (805706)   +5 more
core   +1 more source

A novel function of Escherichia coli transfer RNA nucleotidyltransferase. Biosynthesis of the C-C-A sequence in a phage T4 transfer RNA precursor.

open access: yesJournal of Biological Chemistry, 1975
The biosynthesis of the phage T4-coded proline and serine transfer RNA species proceeds through a precursor RNA containing both tRNA sequences. Neither tRNA sequence in the precursor RNA contains the 3'-terminal C-C-A common to all mature tRNAs. Seidman and McClain ((1975) Proc. Natl. Acad. Sci. U. S. A.
openaire   +2 more sources

Organellar ribonucleases and poly(A) polymerases in Chlamydomonas reinhardtii [PDF]

open access: yes, 2008
RNA catabolism occurs in multiple cellular compartments. This study used the unicellular photosynthetic eukaryote Chlamydomonas reinhardtii to identify a small suite of putatively organellar, nucleus-encoded prokaryotic-like ribonucleases and poly(A ...
Zimmer, Sara
core  

Primer- and template-independent RNA polymerization by terminal nucleotidyltransferase TENT4B

open access: yes
Abstract RNA synthesis by eukaryotic polymerases requires existing polynucleotides to serve as templates or primers. Here, we describe primer- and template-free RNA generation by human terminal nucleotidyltransferase 4B (TENT4B) via de novo polymerization of free nucleotides.
Neha Nagpal   +3 more
openaire   +2 more sources

Biochemical and structural characterization of the RlaP family nucleotidyltransferase potentially involved in RNA repair

open access: yes
Abstract Nucleotidyltransferases (NTases) of Polβ superfamily are highly diverse and play many important biological functions. However, many families of NTases remain uncharacterized. Because of physical proximity of the genes encoding NTases of PF10127 family to those encoding RNA ligases involved in RNA repair ...
Carruthers, Amy   +2 more
openaire   +2 more sources

Confirmation of protein interactions involving tRNA nucleotidyltransferase from yeast two-hybrid data [PDF]

open access: yes, 2004
A transfer RNA (tRNA) requires the nucleotide sequence cytidine, cytidine, adenosine at its 3 ' terminus to be functional. These nucleotides are added by the enzyme ATP (CTP): tRNA-specific tRNA nucleotidyltransferase (tRNA nucleotidyltransferase).
Chang, Wen Tzu
core  

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