Results 81 to 90 of about 5,405 (175)
Journal of Biological Chemistry, 1975 The biosynthesis of the phage T4-coded proline and serine transfer RNA species proceeds through a precursor RNA containing both tRNA sequences. Neither tRNA sequence in the precursor RNA contains the 3'-terminal C-C-A common to all mature tRNAs. Seidman and McClain ((1975) Proc. Natl. Acad. Sci. U. S. A.
openaire +2 more sources
Biophysical and biochemical characterization of yeast tRNA nucleotidyltransferase variants [PDF]
, 2017 The enzyme ATP(CTP):tRNA-specific tRNA nucleotidyltransferase adds cytidine-cytidine-adenosine (CCA) to the 3’ end of eukaryotic tRNAs during their maturation. This CCA sequence plays a vital role in aminoacylation and hence in protein synthesis.
Rahman, Mohammed Samiur
core
, 2014 Post-transcriptional gene regulation mechanisms decide on cellular mRNA activities. Essential gatekeepers of post-transcriptional mRNA regulation are broadly conserved mRNA-modifying enzymes, such as cytoplasmic poly(A) polymerases (cytoPAPs).
Eckmann, C. +3 more
core +1 more source
The identity of the discriminator base has an impact on CCA addition [PDF]
, 2015 CCA-adding enzymes synthesize and maintain the C-C-A sequence at the tRNA 3''-end, generating the attachment site for amino acids. While tRNAs are the most prominent substrates for this polymerase, CCA additions on non-tRNA transcripts are described as ...
Betat, Heike +4 more
core +1 more source
THE IDENTIFICATION OF NOVEL INORGANIC CARBON SENSITIVE ENZYMES [PDF]
, 2010 Adenylyl cyclase catalyses the formation of the second messenger adenosine-3’, 5’-monophosphate from adenosine triphosphate, and is involved in a number of diverse signalling pathways in eukaryotes and prokaryotes.
TOWNSEND, PHILIP,DAVID
core
A LC-MS/MS-Based Approach to Studying the Saccharomyces cerevisiae Cca1 Protein [PDF]
, 2018 The enzyme ATP (CTP): tRNA-specific tRNA nucleotidyltransferase (tRNA-NT) is an essential enzyme in eukaryotes and some prokaryotes and plays a critical role in tRNA maturation. This enzyme is responsible for the addition of AMP and CMP residues to the 3’
Guan, Tian Lai
core
Characterization of Saccharomyces cerevisiae tRNA nucleotidyltransferase variants [PDF]
, 2014 Yeast cells exhibit a temperature-sensitive phenotype at 37°C due to an ATP(CTP): tRNA nucleotidyltransferase variant containing a glutamate to phenylalanine substitution at position 189.
Sandhu, Prit-Kamal Singh
core
Divergent Evolution of Eukaryotic CC- and A-Adding Enzymes [PDF]
Synthesis of the CCA end of essential tRNAs is performed either by CCA-adding enzymes or as a collaboration between enzymes restricted to CC- and A-incorporation. While the occurrence of such tRNA nucleotidyltransferases with partial activities seemed to
Betat, Heike +4 more
core +1 more source
The role of arginine 204 in Candida glabrata tRNA nucleotidyltransferase [PDF]
, 2011 The enzyme ATP(CTP):tRNA nucleotidyltransferase is required for protein synthesis in eukaryotes. It allows for the step-wise addition of a specific cytidine-cytidine-adenosine (CCA) sequence to the 3’ ends of tRNAs without the use of a nucleic acid ...
Colasurdo, Gabriele
core
The role of arginine 244 in Candida glabrata tRNA nucleotidyltransferase [PDF]
, 2009 The enzyme ATP(CTP):tRNA nucleotidyltransferase is essential in eukaryotes to allow tRNAs to participate in protein synthesis. It adds a specific cytidine-cytidine-adenosine (CCA) sequence to generate positions 74, 75, and 76 at the 3' ends of tRNAs in a
Arthur, Jason
core