Results 41 to 50 of about 1,015,959 (268)
Nuclear Positioning in Muscle Development and Disease
Frontiers in Physiology, 2013 Muscle disease as a group is characterized by muscle weakness, muscle loss, and impaired muscle function. Although the phenotype is the same, the underlying cellular pathologies, and the molecular causes of these pathologies, are diverse.
Eric eFolker, Mary eBaylies
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Circadian Organelles: Rhythms at All Scales
Cells, 2021 Circadian clocks have evolved in most light-sensitive organisms, from unicellular organisms to mammals. Consequently, a myriad of biological functions exhibits circadian rhythmicity, from behavior to physiology, through tissue and cellular functions to ...
Rona Aviram, Yaarit Adamovich, Gad Asher
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Leukocyte nucleus segmentation and nucleus lobe counting [PDF]
BMC Bioinformatics, 2010 Abstract Background Leukocytes play an important role in the human immune system. The family of leukocytes is comprised of lymphocytes, monocytes, eosinophils, basophils, and neutrophils. Any infection or acute stress may increase or decrease the number of leukocytes.
Yung-Kuan Chan +4 more
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FEBS Letters, EarlyView.Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi +5 more
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Fractal and Fractional, 2023 Fractal analysis (FA) is a contemporary computational technique that can assist in identifying and assessing nuanced structural alterations in cells and tissues after exposure to certain toxic chemical agents.
Igor Pantic +3 more
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Reciprocal control of viral infection and phosphoinositide dynamics
FEBS Letters, EarlyView.Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
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Cells, 2021 Cells and tissues are continuously exposed to both chemical and physical stimuli and dynamically adapt and respond to this variety of external cues to ensure cellular homeostasis, regulated development and tissue-specific differentiation.
Inmaculada Navarro-Lérida +2 more
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Pion production in nucleus-nucleus collisions [PDF]
AIP Conference Proceedings, 1975 Current work on pion production in high‐energy nucleus‐nucleus collisions is reviewed. The majority of existing data are of the inclusive variety in which a single final state pion is detected. Experimental data are compared and their possible contributions to obtaining new information on nuclear structure is discussed.
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FEBS Letters, EarlyView.Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho +3 more
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Role of the CaV1.2 distal carboxy terminus in the regulation of L-type current
ChannelsL-type calcium channels are essential for the excitation-contraction coupling in cardiac muscle. The CaV1.2 channel is the most predominant isoform in the ventricle which consists of a multi-subunit membrane complex that includes the CaV1.2 pore-forming ...
Felipe Arancibia +5 more
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