Results 51 to 60 of about 1,491,280 (348)

PHOTON EXCHANGE IN NUCLEUS–NUCLEUS COLLISIONS [PDF]

International Journal of Modern Physics A, 2003
The strong electromagnetic fields in peripheral heavy ion collisions give rise to photon–photon and photon–nucleus interactions. I present a general survey of the photon–photon and photon-hadron physics accessible in these collisions. Among these processes I discuss the nuclear fragmentation through the excitation of giant resonances, the Coulomb ...
openaire   +3 more sources

Insights into PI3K/AKT signaling in B cell development and chronic lymphocytic leukemia

FEBS Letters, EarlyView.
This Review explores how the phosphoinositide 3‐kinase and protein kinase B pathway shapes B cell development and drives chronic lymphocytic leukemia, a common blood cancer. It examines how signaling levels affect disease progression, addresses treatment challenges, and introduces novel experimental strategies to improve therapies and patient outcomes.
Maike Buchner
wiley   +1 more source

Endoplasmic reticulum stress-related prognosis signature characterizes the immune landscape and predicts the prognosis of colon adenocarcinoma

Frontiers in Genetics
BackgroundColon adenocarcinoma (COAD) is characterized by high mortality and poor prognosis. Endoplasmic reticulum stress-related gene (ERSG) plays an indispensable role in the progression and immunotherapy of COAD.
Lichao Cao, Lichao Cao, Lichao Cao, Lichao Cao, Haoyang Dai, Haoyang Dai, Shangqing Wei, Shangqing Wei, Ying Ba, Ying Ba, Ying Ba, Fang Chen, Fang Chen, Fang Chen, Yingying Chen, Yingying Chen, Yingying Chen, Chendi Yu, Chendi Yu, Chendi Yu, Shenrui Zhang, Shenrui Zhang, Shenrui Zhang, Erfei Chen, Erfei Chen, Erfei Chen, Hezi Zhang, Hezi Zhang, Hezi Zhang   +28 more
doaj   +1 more source

Five-year follow-up of bilateral stimulation of the subthalamic nucleus in advanced Parkinson's disease.

New England Journal of Medicine, 2003
BACKGROUND Although the short-term benefits of bilateral stimulation of the subthalamic nucleus in patients with advanced Parkinson's disease have been well documented, the long-term outcomes of the procedure are unknown.
P. Krack, A. Batir, N. Van Blercom, S. Chabardès, V. Fraix, C. Ardouin, A. Koudsié, P. Limousin, A. Benazzouz, J. Lebas, A. Benabid, P. Pollak   +11 more
semanticscholar   +1 more source

Making tau amyloid models in vitro: a crucial and underestimated challenge

FEBS Letters, EarlyView.
This review highlights the challenges of producing in vitro amyloid assemblies of the tau protein. We review how accurately the existing protocols mimic tau deposits found in the brain of patients affected with tauopathies. We discuss the important properties that should be considered when forming amyloids and the benchmarks that should be used to ...
Julien Broc, Clara Piersson, Yann Fichou
wiley   +1 more source

Decoding the dual role of autophagy in cancer through transcriptional and epigenetic regulation

FEBS Letters, EarlyView.
Transcriptional and epigenetic regulation controls autophagy, which exerts context‐dependent effects on cancer: Autophagy suppresses tumorigenesis by maintaining cellular homeostasis or promotes tumor progression by supporting survival under stress. In this “In a Nutshell” article, we explore the intricate mechanisms of the dual function of autophagy ...
Young Suk Yu, Ik Soo Kim, Sung Hee Baek
wiley   +1 more source

Viruses in the Nucleus

Cold Spring Harbor Perspectives in Biology, 2021
Viral infection is intrinsically linked to the capacity of the virus to generate progeny. Many DNA and some RNA viruses need to access the nuclear machinery and therefore transverse the nuclear envelope barrier through the nuclear pore complex. Viral genomes then become chromatinized either in their episomal form or upon integration into the host ...
Lucic, B, de Castro, IJ, Lusic, M
openaire   +5 more sources

Autophagy in cancer and protein conformational disorders

FEBS Letters, EarlyView.
Autophagy plays a crucial role in numerous biological processes, including protein and organelle quality control, development, immunity, and metabolism. Hence, dysregulation or mutations in autophagy‐related genes have been implicated in a wide range of human diseases.
Sergio Attanasio
wiley   +1 more source

Role of the CaV1.2 distal carboxy terminus in the regulation of L-type current

Channels
L-type calcium channels are essential for the excitation-contraction coupling in cardiac muscle. The CaV1.2 channel is the most predominant isoform in the ventricle which consists of a multi-subunit membrane complex that includes the CaV1.2 pore-forming ...
Felipe Arancibia, Daniela De Giorgis, Franco Medina, Tamara Hermosilla, Felipe Simon, Diego Varela   +5 more
doaj   +1 more source

Live-Cell Imaging of Rhabdovirus-Induced Morphological Changes in Plant Nuclear Membranes

Molecular Plant-Microbe Interactions, 2005
Potato yellow dwarf virus (PYDV) and Sonchus yellow net virus (SYNV) belong to the genus Nucleorhabdovirus. These viruses replicate in nuclei of infected cells and mature virions accumulate in the perinuclear space after budding through the inner nuclear
Michael Goodin, Sharon Yelton, Debasish Ghosh, Stephanie Mathews, Judith Lesnaw   +4 more
doaj   +1 more source