Results 51 to 60 of about 1,534,545 (314)

Role of the CaV1.2 distal carboxy terminus in the regulation of L-type current

open access: yesChannels
L-type calcium channels are essential for the excitation-contraction coupling in cardiac muscle. The CaV1.2 channel is the most predominant isoform in the ventricle which consists of a multi-subunit membrane complex that includes the CaV1.2 pore-forming ...
Felipe Arancibia   +5 more
doaj   +1 more source

Nuclear Positioning in Muscle Development and Disease

open access: yesFrontiers in Physiology, 2013
Muscle disease as a group is characterized by muscle weakness, muscle loss, and impaired muscle function. Although the phenotype is the same, the underlying cellular pathologies, and the molecular causes of these pathologies, are diverse.
Eric eFolker, Mary eBaylies
doaj   +1 more source

Circadian Organelles: Rhythms at All Scales

open access: yesCells, 2021
Circadian clocks have evolved in most light-sensitive organisms, from unicellular organisms to mammals. Consequently, a myriad of biological functions exhibits circadian rhythmicity, from behavior to physiology, through tissue and cellular functions to ...
Rona Aviram, Yaarit Adamovich, Gad Asher
doaj   +1 more source

Forward Physics in Proton-Nucleus and Nucleus-Nucleus Collisions [PDF]

open access: yesAIP Conference Proceedings, 2008
8 pages, 7 figures. Based on invited talk presented by J.N.
J. Nemchik   +5 more
openaire   +2 more sources

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

Oxidopamine-Induced Nuclear Alterations Quantified Using Advanced Fractal Analysis: Random Forest Machine Learning Approach

open access: yesFractal and Fractional, 2023
Fractal analysis (FA) is a contemporary computational technique that can assist in identifying and assessing nuanced structural alterations in cells and tissues after exposure to certain toxic chemical agents.
Igor Pantic   +3 more
doaj   +1 more source

suppression from hadron-nucleus to nucleus-nucleus collisions

open access: yesNuclear Physics B, 1990
Abstract We explore the combined role of inelastic final-state scattering with nucleons and comoving secondary particles in the suppression of J ψ production for hadron-nucleus and nucleus-nucleus collisions, as functions of target mass, beam energy, and transverse energy.
S. Gavin, R. Vogt
openaire   +1 more source

Nucleus-Nucleus Collisions at Highest Energies [PDF]

open access: yes, 1996
Proc. Int. Conf. on Nuclear Physics at the Turn of the Millenium: Structure of Vacuum and Elementary Matter, 10-16 March 1996, Wilderness/George, South ...
Bleicher, Marcus   +12 more
openaire   +2 more sources

Cortical and Subcortical Contributions to Stop Signal Response Inhibition: Role of the Subthalamic Nucleus

open access: yesJournal of Neuroscience, 2006
Suppressing an already initiated manual response depends critically on the right inferior frontal cortex (IFC), yet it is unclear how this inhibitory function is implemented in the motor system.
A. Aron, R. Poldrack
semanticscholar   +1 more source

The role and implications of mammalian cellular circadian entrainment

open access: yesFEBS Letters, EarlyView.
At their most fundamental level, mammalian circadian rhythms occur inside every individual cell. To tell the correct time, cells must align (or ‘entrain’) their circadian rhythm to the external environment. In this review, we highlight how cells entrain to the major circadian cues of light, feeding and temperature, and the implications this has for our
Priya Crosby
wiley   +1 more source

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