Results 171 to 180 of about 111,869 (302)

Nps‐Expressing Neurons Receive Extensive Input From Auditory Brainstem Nuclei

Journal of Comparative Neurology, Volume 534, Issue 4, April 2026.
Nps‐expressing neurons receive input from auditory brainstem nuclei, with additional afferents from the reticular formation, midbrain, hypothalamus, and extended amygdala. While rabies retrograde labeling in the cerebral cortex was sparse, cholera toxin beta (CTb) revealed copious input, and anterograde tracing identified many axons and boutons ...
Richie Zhang, Silvia Gasparini, Joel C. Geerling   +2 more
wiley   +1 more source

Fenofibrate restores glutamatergic and dopaminergic homeostasis in the nucleus accumbens and reduces alcohol relapse in rats. [PDF]

Front Pharmacol
Isla E, Gutiérrez-Vega I, Quilaqueo ME, Herrera-Marschitz M, Quintanilla ME, Morales P, Pérez-Reytor D, Rivera-Meza M, Karahanian E.   +8 more
europepmc   +1 more source

The Viloxazine Paradox: A Noradrenergic Agent's Journey From Antidepressant Obscurity to ADHD Precision Therapy

CNS Neuroscience &Therapeutics, Volume 32, Issue 4, April 2026.
Viloxazine, a serotonin–norepinephrine modulating agent, has been repurposed from an antidepressant to a novel non‐stimulant for ADHD. Its multimodal mechanism and Phase II/III trials demonstrate clinically meaningful symptom reduction with a distinct safety and interaction profile, offering an alternative for patients who cannot tolerate stimulants ...
Ghaith K. Mansour, Sabry Babiker H. Sayed, Sajjad Ghanim Al‐Badri, Mohammed Gamaleldin Abdulrahim Abdalla, Dina Essam Abo‐elnour   +4 more
wiley   +1 more source

GABAergic Neuron Activation in the RMTg‐VTA Pathway Modulates Dopaminergic Neuron Excitability and Social Stress Susceptibility in Male Mice

CNS Neuroscience &Therapeutics, Volume 32, Issue 4, April 2026.
In susceptible mice, dopamine neurons in the VTA exhibit increased excitability along with upregulation of GABAA receptors. Administration of the GABAA receptor agonist muscimol reduces this neuronal hyperexcitability and reverses social avoidance behavior.
Guang‐Yue Ma, Jin‐Zhu Zhuang, Shu‐Feng Li, Yu‐E Zhang, Di Zhang, Jun Zhao, Zhen Peng, Liu Yang, Zhang Cao, Xin Xie, Rong Jiang, Hui Sun   +11 more
wiley   +1 more source

A Review of Vagus Nerve Stimulation for Disease: Comprehensive Theory and Evidence for Mechanisms of Action

Comprehensive Physiology, Volume 16, Issue 2, April 2026.
Vagus nerve stimulation (VNS) effects span central and peripheral organ systems through diverse mechanistic pathways. This comprehensive review provides a unified synthesis of these mechanisms across neurological, cardiovascular, immunological, metabolic, and gastrointestinal domains, filling a critical gap and serving as a foundational resource for ...
Yifeng Bu, Alex Liang, Benjamin U. Hoffman, Dawn M. Schiehser, Oliver Case, Alan Simmons, Ruth Klaming, Andres Gottfried‐Blackmore, Ravinder K. Mittal, Christopher Puleo, Hubert Lim, Imanuel Lerman   +11 more
wiley   +1 more source

Nucleus Accumbens [PDF]

, 2011
openaire   +1 more source

D1 and D2 neurons in medial nucleus accumbens participate in chronic orofacial pain phenotypes. [PDF]

Pain Rep
Montes-Ángeles CD, Andrade-González RD, Perrusquia-Hernández E, González-Alva P, García-Hernández AL, Pérez-Martínez IO.   +5 more
europepmc   +1 more source

GLP‐1 at the Metabolic–Cognitive Interface: Reward, Affect, and Memory

Comprehensive Physiology, Volume 16, Issue 2, April 2026.
GLP‐1R signaling integrates metabolic state with neural circuits controlling reward, mood, and memory, acting as a metabolic‐cognitive interface. In reward pathways, it suppresses hedonic feeding and drug seeking; in affective circuits, sustained signaling promotes anxiolytic and antidepressant effects; and in the hippocampus, it enhances synaptic ...
Serena X. Gao, Léa Décarie‐Spain, Cindy Gu, Giulia Mazzini, Scott E. Kanoski, Tito Borner   +5 more
wiley   +1 more source

Reduced neural specificity for a romantic partner in the nucleus accumbens over relationship duration. [PDF]

Soc Cogn Affect Neurosci
Fujisaki K, Ueda R, Nakai R, Abe N.
europepmc   +1 more source

Astrocytes as central integrators of neural circuit function: Mechanisms and dysregulation in neuropsychiatric disorders

Clinical and Translational Discovery, Volume 6, Issue 2, April 2026.
1. Astrocytes are central integrators of neural circuit function through tripartite synapse modulation and neurovascular coupling. 2. Dysregulation of glutamate/GABA homeostasis and neuroinflammation represents shared mechanisms across diverse neuropsychiatric disorders. 3.
Xinyu Liu, Xinyue Zhou, Ruotong Meng, Yanxi Chen, You Chen, Blake Highet, Maurice Curtis, Bernhard Hirt, Shunying Yu, Jin Zhou, Linya You   +10 more
wiley   +1 more source