Results 151 to 160 of about 72,699 (283)

Psychedelics as pharmacotherapeutics for substance use disorders: A scoping review on clinical trials and perspectives on underlying neurobiology

British Journal of Pharmacology, Volume 183, Issue 14, Page 4022-4047, July 2026.
Theorized mechanism of dopamine homeostasis restoration in the nucleus accumbens core induced by a psychedelic intervention. Abstract Psychedelics have garnered great attention in recent years as treatments for major depressive disorder (MDD) and treatment‐resistant depression because of their ability to alter consciousness and afflicted cognitive ...
Lucas Wittenkeller, Gary Gudelsky, T. John Winhusen, Davide Amato   +3 more
wiley   +1 more source

Automatic segmentation of Nucleus Accumbens

, 2012
Segmentation of subcortical structures in the brain has become an increasingly important topic in contemporary medicine. The ability to effi ciently isolate different regions of the human brain has allowed doctors and technicians to become more e ...
Sem, Federico
core   +1 more source

Differential effect of NMDA receptor antagonist in the nucleus accumbens on reconsolidation of morphine -related positive and aversive memory in rats

, 2012
Dysfunctional reconsolidation processes may help drug memories resist extinction and contribute to high rate of relapse. Reconsolidation of drug memory is mainly affected by the appetitive and aversive emotional experiences associated with an addictive ...
Sui, Nan, Wu, Yan, Sui, N (reprint author), Chinese Acad Sci, Inst Psychol, Key Lab Mental Hlth, 4A Datun Rd, Beijing 100101, Peoples R China., Li, Yonghui, Gao, Jun   +4 more
core  

In rats, neurodevelopmental disorders induced by maternal hypoxia are associated with attenuated excitatory neurotransmission in the cingulate cortex

British Journal of Pharmacology, Volume 183, Issue 13, Page 3723-3742, July 2026.
Background and Purpose Maternal hypoxia is a recognised risk factor for neurodevelopmental disorders in offspring. Although rodent models of hypoxia have been reported, the detailed pathogenesis of maternal hypoxia‐induced neurodevelopmental disorders remains unclear.
Kentaro Tokudome, Masaaki Ueki, Takujiro Homma, Shinji Matsunaga, Saki Shimizu, Yukihiro Ohno, Shuhei Tomita   +6 more
wiley   +1 more source

Neuromodulator Dynamics Underlying Associative Learning in the Ventral Striatum's Olfactory Tubercle

Advanced Science, Volume 13, Issue 32, 9 June 2026.
Using fiber photometry and genetically encoded sensors, the dynamic release patterns of four neuromodulators in the olfactory tubercle (OT)—a brain region overlapping with the olfactory cortex and ventral striatum—were systematically monitored in response to external rewards and distinct reward‐associated learning processes.
Maojun Hong, Liuting Zou, Yiqing Chen, Juan Guo, Zhixiang Xu, Tong Ma, Shuaishuai Hu, Rongfeng K. Hu   +7 more
wiley   +1 more source

Contributions of the Alzheimer's Disease Neuroimaging Initiative to advancing AD research: a targeted review of recent publications

Alzheimer's &Dementia, Volume 22, Issue 6, June 2026.
Abstract The Alzheimer's Disease Neuroimaging Initiative (ADNI) recently celebrated its 20th anniversary, reflecting two decades of major contributions to Alzheimer's research through open data sharing and longitudinal multimodal assessments. This review synthesizes 122 high‐impact studies using ADNI data or biospecimens from 2023 to mid‐2025 to ...
Dallas P. Veitch, Melanie J. Miller, Shaveta Kanoria, Paul S. Aisen, Laurel A. Beckett, Robert C. Green, Danielle J. Harvey, Clifford R. Jack Jr., William Jagust, Edward B. Lee, Kwangsik Nho, Rachel Nosheny, Ozioma C. Okonkwo, Richard J. Perrin, Ronald C. Petersen, Monica Rivera Mindt, Andrew J. Saykin, Leslie M. Shaw, Arthur W. Toga, Duygu Tosun, Susan M Landau, Michael W. Weiner, for the Alzheimer's Disease Neuroimaging Initiative   +22 more
wiley   +1 more source

How loneliness and social isolation are linked to cognitive decline among older adults? A systematic review of underlying physiological and psychobehavioral mechanisms

Alzheimer's &Dementia, Volume 22, Issue 6, June 2026.
Abstract Despite empirical evidence linking loneliness and social isolation to cognitive decline (CD) in later life, the underlying physiological and psychobehavioral mechanisms remain unclear. We conducted a systematic review to synthesize relevant evidence.
Kexin Yu, Karina Van Bogart, Jee Eun Kang, Harry O. Taylor, Karra D. Harrington, Lisa C. Silbert, Ihab Hajjar, Hiroko H. Dodge   +7 more
wiley   +1 more source

Pubertal isolation alters latent inhibition and DA in nucleus accumbens of adult rats

, 2009
Puberty is a critical period for neurodevelopment of schizophrenia. In the present study, we investigated the effects of peri-pubertal social isolation on psychotic behaviors in rats and its relationship to dopamine expression.
Jin, Jian, Meng, Qingxuan, Wang, Weiwen, W. W. Wang, Shao, Feng, Lin, Wenjuan, Xie, Xi, Liu, Mei   +7 more
core  

Structural Connectivity of Functionally Defined Episodic Memory Networks: A Large‐Scale Connectome–Behavior Study

Brain and Behavior, Volume 16, Issue 6, June 2026.
Abstract Background Previous task‐based fMRI work in a large cohort of young adults identified nine large‐scale functional brain networks whose encoding‐related responsivity was robustly associated with individual differences in episodic memory. It remains unclear whether structural connectivity within these task‐fMRI‐defined networks explains inter ...
Neda Ghasemi, David Coynel, Andreas Papassotiropoulos, Dominique J. F. de Quervain   +3 more
wiley   +1 more source

Dopamine in the Nucleus Accumbens Signals Salience of Auditory Deviance. [PDF]

Eur J Neurosci
Iizuka R, Yamaki R, Isoguchi Shiramatsu T, Morikawa S, Ikegaya Y, Takahashi H.   +5 more
europepmc   +1 more source