Results 151 to 160 of about 376,324 (266)

Psychiatric effects of cannabidiol, cannabinol, and tetrahydrocannabinol: A narrative review of clinical evidence and risk profiles

Psychiatry and Clinical Neurosciences Reports, Volume 5, Issue 3, September 2026.
Abstract Cannabinoid products are increasingly used worldwide despite limited psychiatric evidence. This narrative review synthesizes preclinical and clinical evidence on cannabidiol (CBD), cannabinol (CBN), and tetrahydrocannabinol (THC) to clarify their distinct psychiatric profiles and discuss how current evidence may inform ongoing clinical and ...
Yasuhiro Kishi, Ichiro Takumi, Kakusho Chigusa Nakajima‐Ohyama   +2 more
wiley   +1 more source

Duration-dependent attenuation of nucleus accumbens synchronisation via noninvasive temporal interference. [PDF]

Gen Psychiatr
Zang Z, Zhang Y, Li C, Yang Z.
europepmc   +1 more source

The neuropsychological impact of early childhood trauma on cognitive development: A narrative review of mechanisms, outcomes, and interventions

Psychiatry and Clinical Neurosciences Reports, Volume 5, Issue 3, September 2026.
Abstract Research indicates that early traumatic experiences can profoundly affect a child's ability to manage emotions, develop social skills, and adapt effectively. Still, the impact of trauma on children goes beyond just emotional and behavioral dimensions.
Kalliopi Megari, Kremena Dinkova Genova
wiley   +1 more source

Obesity is associated with greater variability of reward signals in the nucleus accumbens. [PDF]

Transl Psychiatry
van den Hoek Ostende MM, Kühnel A, Neuser MP, Dresler T, Svaldi J, Kroemer NB.   +5 more
europepmc   +1 more source

Research Progress on the Regulatory Mechanisms of Gut Microbiota in Methamphetamine Addiction and Targeted Interventions

Addiction Biology, Volume 31, Issue 9, September 2026.
ABSTRACT Methamphetamine (METH) is a globally prevalent, highly addictive synthetic psychostimulant, for which no FDA‐approved pharmacotherapy is currently available for METH use disorder (MUD). The microbiota–gut–brain axis has been well established as a key regulatory pathway in substance use disorders, yet its specific mechanistic basis and ...
Jihao Yang, Yishuang Dai, Jia Li
wiley   +1 more source

Nucleus accumbens DRD2 receptor agonism attenuates escape behavior. [PDF]

Front Neurosci
Côté BE, Grafelman EM, Moster L, Zimolzak K, Hix HE, Cooper M, Padula GN, Wheeler DS, Hearing MC, Mantsch JR, Wheeler RA.   +10 more
europepmc   +1 more source

Inhibition of kynurenine 3‐monooxygenase (KMO) reduces fentanyl and sucrose intake and relapse‐like behaviour in rats

British Journal of Pharmacology, Volume 183, Issue 18, Page 5458-5475, September 2026.
Abstract Background and Purpose Opioid use disorder, particularly involving fentanyl, poses major challenges due to high relapse rates and limited effectiveness of pharmacotherapies. The kynurenine pathway has emerged as a target for addiction treatment through its modulation of glutamatergic and dopaminergic neurotransmission.
Carlos Núñez‐de la Calle, Lluna Careaga, Stefanie Malan‐Müller, Álvaro del Río‐García, Yaiza Trueba, Leticia Gil de Biedma‐Elduayen, Nuria Morales‐Puerto, Rebeca Vidal, Åsa Wiman, Sophie Erhardt, María Dolores Gutiérrez‐López, Esther O'Shea, María Isabel Colado   +12 more
wiley   +1 more source

A cholinergic hub in the nucleus accumbens gates opioid-reward learning. [PDF]

Nature
Yousefzadeh SA, Yan H, Kwak SH, Oh Y, Jeong P, Pogorelov V, Ravenel JR, Lim SSX, Roach JM, Shields BC, Rodriguiz RM, Wetsel WC, Hong J, Tadross MR.   +13 more
europepmc   +1 more source

Genetic Parameters and Genome‐Wide Association Studies for Fertility and Reproduction Traits in U.S. Katahdin Sheep Based on the Single‐Step GBLUP Methodology

Journal of Animal Breeding and Genetics, Volume 143, Issue 5, Page 625-638, September 2026.
ABSTRACT Sheep production contributes to a secure and diverse food and fibre supply in the United States, with growing ethnic diversity strengthening demand. Katahdin is a composite hair‐type sheep breed developed in the United States that has become the most popular breed in many regions of the country and the first one to have genomic selection ...
Alejandra Toro Ospina, Ronald M. Lewis, Bradley A. Freking, Joan M. Burke, Thomas W. Murphy, Carrie S. Wilson, Luiz F. Brito   +6 more
wiley   +1 more source

Altered Postnatal Chromatin Development in the Nucleus Accumbens Primes Enduring Stress Sensitivity. [PDF]

J Neurosci
Rashford RL, Fang LZ, DeBerardine M, Kim HJJ, Hirschfield LW, Cervi E, Barrett MR, Thompson JM, Creed MC, Peña CJ.   +9 more
europepmc   +1 more source