Results 131 to 140 of about 72,699 (283)

The altered volume of striatum: A neuroimaging marker of treatment in first-episode and drug-naïve schizophrenia

Schizophrenia Research: Cognition
Although schizophrenia patients exhibit structural abnormalities in the striatum, it remains largely unknown for the role of the striatum subregions in the treatment response of antipsychotic drugs.
Gao-Xia Wei, Haoran Shen, Li-Kun Ge, Bo Cao, Roja Manohar, Xiangyang Zhang   +5 more
doaj   +1 more source

Knocking Down the DRD2 by shRNA Expressing Plasmids in the Nucleus Accumbens Prevented the Disrupting Effect of Apomorphine on Prepulse Inhibition in Rat [PDF]

Journal of Sciences, Islamic Republic of Iran, 2015
Prepulse Inhibition (PPI), the objective measure of sensorimotor gating disturbance has being widely used in animal models of schizophrenia. Dopaminergic direct and indirect agonists impair PPI.
M.R. Noori-daloii, A. Shahbazi, S. Alizadeh Zendehrood, A. Shayan Nia, M. Mojarrad, M. Kheirollahi, A. Rashidi-Nezhad, A. Haghparast, F. Zare Mehrjerdi, S. Niknazar, M. Mostowfi, H. Hashemi Sotoobadi, M. Khaksari, A. R. Noori-Daloii, A. Mohammadi   +14 more
doaj  

Mesocorticolimbic circuitry in episodic migraine: reward- and punishment-related responses and resting-state connectivity

The Journal of Headache and Pain
Background Clinical evidence suggests an involvement of the dopaminergic system in migraine pathophysiology; however, its functional role remains poorly understood.
Stefania Ferraro, Menghan Li, Dan Liu, Yali Zhou, Yiqi Mi, Shengkun Peng, Longlin Yin, Bin Huang, Luca Giani, Keith M. Kendrick, Michael Maes, Benjamin Becker   +11 more
doaj   +1 more source

Characteristic fMRI BOLD response to ghrelin in the nucleus accumbens.

, 2014
a. Position of the nucleus accumbens (highlighted in red) is shown in a horizontal scheme of the rat brain [44]. b. Ghrelin evoked a negative BOLD response in the nucleus accumbens. Slice thickness is 1 mm.
Miklós Sárvári (466921), Zsolt Liposits (88218), Nikolett Hegedűs (564704), Zsófia Pozsgay (564703), Szabolcs Dávid (564702), Levente Deli (564700), Dávid Gajári (564701), Pál Kocsis (564699), Károly Tihanyi (564705)   +8 more
core   +1 more source

Abstinence from cocaine self-administration promotes microglial pruning of astrocytes, which drives cocaine-seeking behavior

Cell Reports
Summary: Rodent drug self-administration leads to a compromised ability of nucleus accumbens astrocytes to maintain glutamate homeostasis as well as to reductions in surface area, volume, and synaptic colocalization of astrocyte membranes.
Anze Testen, Jonathan W. VanRyzin, Tania J. Bellinger, Ronald Kim, Han Wang, Matthew J. Gastinger, Emily A. Witt, Janay P. Franklin, Haley A. Vecchiarelli, Katherine Picard, Michael D. Scofield, Marie-Ève Tremblay, Kathryn J. Reissner   +12 more
doaj   +1 more source

Innovations in Obesity Treatment: Beyond Adipose Tissue Dysfunction

Obesity Reviews, EarlyView.
Obesity drives chronic inflammation, insulin resistance, type 2 diabetes, and cancer development through adipocyte dysfunction. Addressing this multisystemic disorder requires integrated strategies beyond diet and exercise, such as thermogenesis activation via menthol or capsinoids and appetite control through GLP‐1/GIP agonists and neuromodulation to ...
Jesica Martínez‐Godfrey, Irene Pomares‐Bri, Paula de Juan‐Maciá, Mariló Olivares‐Vicente, Enrique Barrajón‐Catalán, Vicente Micol, Enrique Roche, María Herranz‐López   +7 more
wiley   +1 more source

How does the nucleus accumbens tick?

, 2000
El nucleus accumbens se considera una interfase neural entre motivación y acción motora, y participa de modo decisivo en la ingesta, conducta sexual, recompensa, respuesta al estrés, autoadminstración de drogas, etc. Desarrollo.
Fernández-Espejo, Emilio
core  

Glutamate Inputs to the Nucleus Accumbens: Does Source Matter?

, 2012
How the nucleus accumbens integrates information from multiple upstream regions has been a central question for decades. In this issue of Neuron, Britt et al. (2012) photostimulate glutamatergic axons from the amygdala, prefrontal cortex, and hippocampus
Tye, Kay M., Tye, Kay
core   +1 more source

Canonical and non‐canonical functions of proteins regulating mitochondrial dynamics in mammalian physiology

The Journal of Physiology, EarlyView.
Abstract figure legend Mitochondria are highly dynamic organelles that continuously remodel their architecture through coordinated cycles of fusion and fission. This review examines the four key GTPases that orchestrate mitochondrial dynamics in mammals: MFN1, MFN2, OPA1, and DRP1.
Rémi Chaney, Vincent Marcangeli, Krystel Desjardins, Shima Taherkhani, Gilles Gouspillou   +4 more
wiley   +1 more source

Mitochondrial control of ciliary gene expression and structure in striatal neurons

The Journal of Physiology, EarlyView.
Abstract figure legend Neurons drive animal behaviour by receiving and transmitting information and require energy, primarily supplied by mitochondria, to function. Additionally, neurons need to sense environmental changes to adapt, a function that is locally played by the primary cilia.
Dogukan H. Ulgen, Alessandro Chioino, Olivia Zanoletti, Albert Quintana, Elisenda Sanz, Carmen Sandi   +5 more
wiley   +1 more source