Results 121 to 130 of about 111,869 (302)
The Acetylcholine Esterase Inhibitor Donepezil Increases Dopamine Levels in the Nucleus Accumbens and Blocks the Alcohol Deprivation Effect in Rats. [PDF]
Addict BiolThis study examined the effects of donepezil on mesolimbic dopamine signalling and alcohol‐related behaviours in male rats. Donepezil increases nucleus accumbens dopamine via muscarinic mechanisms and prevented further dopamine elevation after alcohol administration. Although it did not reduce regular alcohol intake, it abolished relapse‐like drinking.
Loftén A +4 more
europepmc +2 more sources
Nucleus accumbens activation mediates the influence of reward cues on financial risk-taking [PDF]
In functional magnetic resonance imaging (FMRI) research, nucleus accumbens (NAcc) activation spontaneously increases prior to financial risk taking.
Knutson, Brian +3 more
core +1 more source
Perspective: Depression in Persons with Parkinson's Disease
Movement Disorders, EarlyView.Abstract Depression is a prevalent and disabling syndrome characterized by sustained sadness and/or anhedonia, as well as cognitive and physical symptoms. In Parkinson's disease (PD), depression is both common and clinically challenging due to overlapping symptoms and complex etiologic interactions. Major depressive disorder occurs in approximately 17%
Albert F.G. Leentjens +1 more
wiley +1 more source
Behavioral and pharmacological characterization of a mouse model of palatable diet alternation [PDF]
, 2017 Obesity and eating disorders represent a severe problem in Western societies. Both the increased availability of highly palatable foods and dieting are major risk factors contributing to the epidemic disorders of feeding. The purpose of this study was to
Schlain, Gabrielle Star
core
¿Cómo funciona el nucleus accumbens? [PDF]
Revista de Neurología, 2000 O nucleus accumbens é considerado uma interfase neural entre a motivaçao, conduta sexual, resposta ao stress, autoadministraçao de drogas, etc. Desenvolvimento. O nucleus accumbens apresenta dois territórios, o núcleus e a cobertura, cujas conexoes desenham nitidamente as suas vertentes motora e límbica.
openaire +3 more sources
Addiction, EarlyView.Abstract Background and aims Tobacco smoking is a major risk factor for cardiovascular and lung diseases. A better understanding of its neurobiological underpinnings will benefit the prevention of smoking‐related illnesses and mortality. Previous studies link smoking to increased iron concentration in the striatum, a central component of the brain's ...
Olga Trofimova +2 more
wiley +1 more source
Frontiers in Neuroscience, 2017 The human nucleus accumbens is a challenging region to study using proton magnetic resonance spectroscopy (1H-MRS) on a 70-cm wide-bore clinical 3T MRI system.
Xi-Long Liu +5 more
doaj +1 more source
Addiction, EarlyView.Abstract Background and aims Cannabis is the most widely used illicit drug worldwide and is often co‐used with tobacco, the leading cause of preventable death. Although cannabis and tobacco have distinct neurobiological actions, their associations with brain volumes are unclear.
Katherine Sawyer +16 more
wiley +1 more source
British Journal of Pharmacology, EarlyView.Theorized mechanism of dopamine homeostasis restoration in the nucleus accumbens core induced by a psychedelic intervention. Abstract Psychedelics have garnered great attention in recent years as treatments for major depressive disorder (MDD) and treatment‐resistant depression because of their ability to alter consciousness and afflicted cognitive ...
Lucas Wittenkeller +3 more
wiley +1 more source
Effects of Memantine, an NMDA Antagonist, on Metabolic Syndromes in Female NMRI Mice
Basic and Clinical Neuroscience, 2015 Introduction: The brain glutamate neurotransmitter system and its NMDA receptors in the nucleus accumbens play an important role in the incidence of the phenomena of sensitivity and addiction. The present study examined the inhibitory effect of glutamate
Naser Osanloo +5 more
doaj