Results 121 to 130 of about 376,324 (266)

Nucleus accumbens-associated protein 1 (NAC1) expression.

open access: yes, 2015
Nucleus accumbens-associated protein 1 (NAC1) expression.
Takahiro Kanno (680073)   +7 more
core   +1 more source

Prescription Sequence Symmetry Analysis of Glucagon‐Like Peptide‐1 Receptor Agonists and Neuropsychiatric Conditions

open access: yesClinical Pharmacology &Therapeutics, Volume 120, Issue 4, Page 1092-1100, October 2026.
Glucagon‐like peptide‐1 receptor agonists (GLP‐1RAs) are increasingly prescribed for type 2 diabetes and weight management. However, conflicting evidence from preclinical, clinical, and pharmacovigilance studies suggests potential neuropsychiatric effects.
Maria J. Alfonso Arvez   +6 more
wiley   +1 more source

Nucleus accumbens to globus pallidus GABA projection subserving ambulatory activity

open access: yes, 1980
The present experiments investigated the hypothesis of a projection relating to the release of gamma-aminobutyric acid (GABA) from the nucleus accumbens to the globus pallidus subserving ambulatory activity in the rat.
G. J. Mogenson, D. L. Jones
core   +1 more source

Knocking Down the DRD2 by shRNA Expressing Plasmids in the Nucleus Accumbens Prevented the Disrupting Effect of Apomorphine on Prepulse Inhibition in Rat [PDF]

open access: yesJournal of Sciences, Islamic Republic of Iran, 2015
Prepulse Inhibition (PPI), the objective measure of sensorimotor gating disturbance has being widely used in animal models of schizophrenia. Dopaminergic direct and indirect agonists impair PPI.
M.R. Noori-daloii   +14 more
doaj  

The Astrocyte Clock Controls Circadian Perineuronal Net Remodeling, Synapse Strength and Learning Behavior

open access: yesGlia, Volume 74, Issue 10, October 2026.
Bmal1 regulates astrocyte extracellular matrix (ECM) gene expression. Bmal1 deletion in astrocytes disrupts normal circadian rhythms in perineuronal nets (PNN) and reduces PNN content in the hippocampus. In parallel with loss of PNNs, deletion of the core circadian clock gene Bmal1 in astrocytes alters behavior and synaptic function in vivo.
Philip C. Smith   +6 more
wiley   +1 more source

Nucleus accumbens

open access: yes, 1997
Nucleus accumbens. Coronal plane.

core  

Mesocorticolimbic circuitry in episodic migraine: reward- and punishment-related responses and resting-state connectivity

open access: yesThe Journal of Headache and Pain
Background Clinical evidence suggests an involvement of the dopaminergic system in migraine pathophysiology; however, its functional role remains poorly understood.
Stefania Ferraro   +11 more
doaj   +1 more source

The altered volume of striatum: A neuroimaging marker of treatment in first-episode and drug-naïve schizophrenia

open access: yesSchizophrenia Research: Cognition
Although schizophrenia patients exhibit structural abnormalities in the striatum, it remains largely unknown for the role of the striatum subregions in the treatment response of antipsychotic drugs.
Gao-Xia Wei   +5 more
doaj   +1 more source

Muscarinic agonists for schizophrenia: Bridging preclinical evidence and clinical enthusiasm

open access: yesBritish Journal of Pharmacology, Volume 183, Issue 19, Page 5701-5731, October 2026.
Abstract Antipsychotic drugs targeting dopamine receptors have been used to treat schizophrenia for decades, primarily alleviating positive symptoms such as hallucinations and delusions. However, they provide limited benefit for cognitive and negative symptoms—major contributors to poor outcomes—and are frequently associated with significant side ...
Brian J. Morris, Judith A. Pratt
wiley   +1 more source

A Depolarizing Leak in Sodium Bicarbonate Cotransporter NBCe1 Causes Brain Edema

open access: yesAnnals of Clinical and Translational Neurology, Volume 13, Issue 9, Page 1817-1830, September 2026.
ABSTRACT Objectives SLC4A4 encodes electrogenic sodium bicarbonate cotransporter NBCe1, prominently expressed in kidney and brain. Recessive loss‐of‐function variants in SLC4A4 cause proximal renal tubular acidosis, no brain edema. In the brain, NBCe1 is expressed by astrocytes, where it regulates pH and mediates astrocyte volume changes.
Quinty Bisseling   +16 more
wiley   +1 more source

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