Results 51 to 60 of about 1,082,587 (269)
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
An Implementation of the Number Field Sieve [PDF]
The Number Field Sieve (NFS) is the asymptotically fastest known factoring algorithm for large integers. This article describes an implementation of the NFS, including the choice of two quadratic polynomials, both classical sieving and a special form of lattice sieving (line sieving), the block Lanczos method and a new square root algorithm.
openaire +3 more sources
Diversity and complexity in neural organoids
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
Units in families of totally complex algebraic number fields
Multidimensional continued fraction algorithms associated with GLn(ℤk), where ℤk is the ring of integers of an imaginary quadratic field K, are introduced and applied to find systems of fundamental units in families of totally complex algebraic number ...
L. Ya. Vulakh
doaj +1 more source
About the Entropy of a Natural Number and a Type of the Entropy of an Ideal
In this article, we find some properties of certain types of entropies of a natural number. We are studying a way of measuring the “disorder” of the divisors of a natural number. We compare two of the entropies H and H¯ defined for a natural number.
Nicuşor Minculete, Diana Savin
doaj +1 more source
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas +3 more
wiley +1 more source
Invariants of number fields related to central embedding problems
Every central embedding problem over a number field becomes solvable after enlarging its kernel in a certain way. We show that these enlargements can be arranged in a universal way.
H. Opolka
doaj +1 more source
The unit group of some fields of the form $\mathbb{Q}(\sqrt2, \sqrt{p}, \sqrt{q}, \sqrt{-l})$ [PDF]
Let $p$ and $q$ be two different prime integers such that $p\equiv q\equiv3\pmod8$ with $(p/q)=1$, and $l$ a positive odd square-free integer relatively prime to $p$ and $q$.
Moha Ben Taleb El Hamam
doaj +1 more source

