Results 61 to 70 of about 4,829,005 (281)

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Computation of relative integral bases for algebraic number fields

International Journal of Mathematics and Mathematical Sciences, 1988
At first we are given conditions for existence of relative integral bases for extension (K;k)=n. Then we will construct relative integral bases for extensions OK6(−36)/Ok2(−3), OK6(−36)/Ok3(−33), OK6(−36)/Z.
Mahmood Haghighi
doaj   +1 more source

Exceptional jumps of Picard ranks of reductions of K3 surfaces over number fields

Forum of Mathematics, Pi, 2022
Given a K3 surface X over a number field K with potentially good reduction everywhere, we prove that the set of primes of K where the geometric Picard rank jumps is infinite.
Ananth N. Shankar, Arul Shankar, Yunqing Tang, Salim Tayou   +3 more
doaj   +1 more source

On Mertens-Ces\`aro Theorem for Number Fields

, 2015
Let $K$ be a number field with ring of integers $\mathcal O$. After introducing a suitable notion of density for subsets of $\mathcal O$, generalizing that of natural density for subsets of $\mathbb Z$, we show that the density of the set of coprime $m ...
Ferraguti, Andrea, Micheli, Giacomo
core   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions

FEBS Letters, EarlyView.
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf, Nicholas F. Downing, Kaitlyn M. Mills, Samuel C. Metcalfe, Alexander E. Kritzer, Lindsey D. Mayo, Peter C. Hollenhorst   +6 more
wiley   +1 more source

Monogenity and Power Integral Bases: Recent Developments

Axioms
Monogenity is a classical area of algebraic number theory that continues to be actively researched. This paper collects the results obtained over the past few years in this area.
István Gaál
doaj   +1 more source

The newfound relationship between extrachromosomal DNAs and excised signal circles

FEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

FEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva, Puspa Kunwar, Md Ibnul Rifat Rahman, Joanna Koryo Kwao, Nathan Lehman, Zihan Zhang, Trenton Paul, Claire Cheng, Nicholas Truex, Hui‐Ting Lee, Jun Zhang   +10 more
wiley   +1 more source

On monogenity of certain pure number fields of degrees $2^r\cdot3^k\cdot7^s$ [PDF]

Mathematica Bohemica
Let $K = \mathbb{Q} (\alpha) $ be a pure number field generated by a complex root $\alpha$ of a monic irreducible polynomial $ F(x) = x^{2^r\cdot3^k\cdot7^s} -m \in\bb{Z}[x]$, where $r$, $k$, $s$ are three positive natural integers.
Hamid Ben Yakkou, Jalal Didi
doaj   +1 more source