Results 71 to 80 of about 4,819,757 (284)

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

On the number of irreducible polynomials of special kinds in finite fields

AIMS Mathematics, 2020
Let $\mathbb{F}_q$ be the finite field of order $q$ and $f(x)$ be an irreducible polynomial of degree $n$ over $\mathbb{F} _q$. For a positive divisor $n_1$ of $n$, define the $n_1$-traces of $f(x)$ to be $\mathrm{Tr}(\alpha;n_1)=\alpha+\alpha^q+\cdots ...
Weihua Li, Chengcheng Fang, Wei Cao
doaj   +1 more source

By dawn or dusk—how circadian timing rewrites bacterial infection outcomes

FEBS Letters, EarlyView.
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo, Catherine S. Palmer, Jacqueline M. Kimmey   +2 more
wiley   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

On monogenity of certain pure number fields of degrees $2^r\cdot3^k\cdot7^s$ [PDF]

Mathematica Bohemica
Let $K = \mathbb{Q} (\alpha) $ be a pure number field generated by a complex root $\alpha$ of a monic irreducible polynomial $ F(x) = x^{2^r\cdot3^k\cdot7^s} -m \in\bb{Z}[x]$, where $r$, $k$, $s$ are three positive natural integers.
Hamid Ben Yakkou, Jalal Didi
doaj   +1 more source

The role and implications of mammalian cellular circadian entrainment

FEBS Letters, EarlyView.
At their most fundamental level, mammalian circadian rhythms occur inside every individual cell. To tell the correct time, cells must align (or ‘entrain’) their circadian rhythm to the external environment. In this review, we highlight how cells entrain to the major circadian cues of light, feeding and temperature, and the implications this has for our
Priya Crosby
wiley   +1 more source

On some differences between number fields and function fields

, 2016
The analogy between the arithmetic of varieties over number fields and the arithmetic of varieties over function fields is a leading theme in arithmetic geometry. This analogy is very powerful but there are some gaps.
Gasbarri, Carlo
core  

Molecular bases of circadian magnesium rhythms across eukaryotes

FEBS Letters, EarlyView.
Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley   +1 more source

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

FEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source

Average Analytic Ranks of Elliptic Curves over Number Fields

Forum of Mathematics, Sigma
We give a conditional bound for the average analytic rank of elliptic curves over an arbitrary number field. In particular, under the assumptions that all elliptic curves over a number field K are modular and have L-functions which satisfy the ...
Tristan Phillips
doaj   +1 more source