Results 71 to 80 of about 2,209 (285)
Numerical Experiments in Collisionless Systems [PDF]
Gravitational n-body calculations handling 105 particles have become routine in the last three or four years. The plasma physicists have also run calculations with comparable numbers of particles – you will hear of these from Dawson this afternoon. In the stellar dynamics area, two groups have been making these calculations – our own group with Kevin ...
openaire +1 more source
The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga +3 more
wiley +1 more source
A Cognitive Taxonomy of Numeration Systems
In this paper, we study the representational properties of numeration systems. We argue that numeration systems are distributed representationsÑrepresentations that are distributed across the internal mind and the external environment.
Jiajie Zhang
core
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure +3 more
wiley +1 more source
Bertrand numeration systems and recognizability
There exist various well-known characterizations of sets of numbers recognizable by a finite automaton, when they are represented in some integer base p⩾2.
Bruyère, Véronique, Hansel, Georges
core +1 more source
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai +4 more
wiley +1 more source
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace +6 more
wiley +1 more source
Numerical Treatment of Catenary Systems [PDF]
AbstractSimulation is of great importance in the development of railway cable systems. Mathematical models and numerical methods for the computation of both static equilibria and dynamic oscillations of railroad catenaries are being derived. These cable systems form a complex network of string and beam elements and lead to coupled partial differential ...
openaire +1 more source
Phosphoinositides and inositol phosphates as molecular glues
Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry +9 more
wiley +1 more source

