Results 101 to 110 of about 4,850,865 (288)
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Liver organoids: modelling complexity in homeostasis and disease
FEBS Letters, EarlyView.Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
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Input data for numerical example network.
, 2017 Input data for numerical example network.
Lili Lu (408133) +3 more
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Epigenetic reprogramming of lineage switching in cancer
FEBS Letters, EarlyView.Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı +4 more
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Basic input parameters of numerical example.
, 2017 Basic input parameters of numerical example.
Dezhi Zhang (3685177) +3 more
core +1 more source
Nonlinear Dynamics of the Vehicle-Bridge Coupled Interaction System
Nonlinear Engineering, 2013 Considering geometry nonlinear of the bridge, the differential equations of vehicle-bridge coupled interaction system are established. Using numerical method, the numerical solution of the coupling nonlinear differential equation are obtained.
Qian C.Z., Chen C.P., Hong L., Zhou G.W.
doaj +1 more source
The microbiome in human skin aging
FEBS Letters, EarlyView.Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana +3 more
wiley +1 more source
Finance performance and statistics of numerical example.
, 2018 Finance performance and statistics of numerical example.
Gilberto de Miranda Júnior (5019236) +4 more
core +1 more source
Finite Difference Method for Two-Dimensional Fractional Partial Differential Equation with parameter
Ibn Al-Haitham Journal for Pure and Applied Sciences, 2017 In this paper, we introduce and discuss an algorithm for the numerical solution of two- dimensional fractional partial differential equation with parameter.
I. I. Gorial
doaj
FEBS Letters, EarlyView.This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source