Results 111 to 120 of about 4,850,865 (288)
Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network
FEBS Letters, EarlyView.Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley +1 more source
Simulated data set for exponential numerical example.
, 2018 Simulated data set for exponential numerical example.
Dan Yu (214174) +3 more
core +1 more source
On solving the plateau problem in parametric form
International Journal of Mathematics and Mathematical Sciences, 1983 This paper presents a numerical method for finding the solution of Plateau's problem in parametric form. Using the properties of minimal surfaces we succeded in transferring the problem of finding the minimal surface to a problem of minimizing a ...
Baruch cahlon +2 more
doaj +1 more source
FEBS Letters, EarlyView.Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante +10 more
wiley +1 more source
Simulated data set for Weibull numerical example.
, 2018 Simulated data set for Weibull numerical example.
Dan Yu (214174) +3 more
core +1 more source
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
FEBS Letters, EarlyView.EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
Pre-specified parameters for exponential numerical example.
, 2018 Pre-specified parameters for exponential numerical example.
Dan Yu (214174) +3 more
core +1 more source
Emerging experimental and computational methods for studying redox‐regulated structural transitions
FEBS Letters, EarlyView.Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
FailureCriteriaandtheYieldCriterionintheNumericalCalculationsofSlopeStability
工程科学与技术, 2014 :The failure criteria and failure models of slopes in the numerical calculations of slope stability were discussed extensively by using theoretical analysis and two typical examples.Qualitative mechanical analyses showed that, if subjective factor was ...
周正军 +4 more
doaj
Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding
FEBS Letters, EarlyView.In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança +2 more
wiley +1 more source