Results 51 to 60 of about 4,212,854 (223)
Earth, Planets and Space, 2012 We use a two-dimensional tsunami sediment transport model to study the source of the 2004 earthquake. To test the model behavior, numerical experiment on sediment deposition and erosion is performed using various hypothetical parameters of tsunami ...
Aditya Riadi Gusman +2 more
doaj +1 more source
Геодинамика и тектонофизика, 2015 The Baikal rift is characterized by high heat flow, seismic activity and large thickness of sediments through which gas and hydrothermal water are intensely released into the lake water.
V. I. Gunin
doaj +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
FEBS Letters, EarlyView.The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi +6 more
wiley +1 more source
Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
Influence of structural parameters of the masonry on effective elastic properties and strength
Инженерно-строительный журнал, 2014 Two phase masonry model, which contains elastic mortar and elastic bricks, is analyzed numerically in order to evaluate sensitivity of effective elastic moduli and strength properties to a deviation in the masonry structural parameters. Different methods
А.I. Grishchenko +3 more
doaj +1 more source
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
A continual model of damaged media for describing the creep failure process
Учёные записки Казанского университета: Серия Физико-математические науки, 2019 The main laws of deformation and degradation processes of the initial strength properties of structural materials (metals and their alloys) according to the long-term strength mechanism were considered.
I.V. Volkov +2 more
doaj +1 more source
An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes
FEBS Letters, EarlyView.GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg +14 more
wiley +1 more source
The history of public health entomology at the Connecticut Agricultural Experiment Station 1904-2009
, 2010 Title from PDF t.p. (publisher's Web site, viewed June 3, 2011).; Includes bibliographical references (p.
Anderson, John Frederic, 1936-
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