Results 41 to 50 of about 4,212,854 (223)
FEBS Letters, EarlyView.This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley +1 more source
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
FEBS Letters, EarlyView.We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace +6 more
wiley +1 more source
AxiomsA reduced-dimension (RD) method based on the proper orthogonal decomposition (POD) technology and the linearized Crank–Nicolson mixed finite element (CNMFE) scheme for solving the 2D nonlinear extended Fisher–Kolmogorov (EFK) equation is proposed.
Xiaohui Chang, Hong Li
doaj +1 more source
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
FEBS Letters, EarlyView.Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
Sensitivity of the Intensity and Structure of Tropical Cyclones to Tropospheric Stability Conditions
Atmosphere, 2020 The intensity of tropical cyclones (TCs) is controlled by their environmental conditions. In addition to the sea surface temperature, tropospheric temperature lapse rate and tropopause height are highly variable.
Tetsuya Takemi, Shota Yamasaki
doaj +1 more source
Method for calculating a two-stage thermoelectric system for local hypothermia
Вестник Дагестанского государственного технического университета: Технические науки, 2023 . Objective. The aim of the study is to develop a methodology for calculating a two-cascade thermoelectric system (TPS) for local hypothermia, as well as a theoretical analysis of its operation.Method.
Z. M.-Z. Badrudinova +4 more
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Modelling stem cell differentiation related processes—A practical overview for biologists
FEBS Letters, EarlyView.Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
Учёные записки Казанского университета: Серия Физико-математические науки, 2019 The problem of identifying the mechanical characteristics of a fibrous compo site material (FCM), from which cylindrical panels or pre-curved plates are made by superposition at an angle to the edge, has been considered. The problem has been solved using
R.A. Kayumov +3 more
doaj +1 more source
FEBS Letters, EarlyView.CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens +8 more
wiley +1 more source