Results 61 to 70 of about 270,289 (306)

Modelling of Single-Gas Adsorption Isotherms

open access: yesMetals, 2022
The present paper reviews and analyses different models that could be used to describe the adsorption equilibrium of pure gases. The adsorption equilibrium of hydrogen, nitrogen and methane is characterised and modelled. Several thermodynamic conceptions
Chavdar Chilev   +3 more
doaj   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Numerical experiment and a case study of sediment transport simulation of the 2004 Indian Ocean tsunami in Lhok Nga, Banda Aceh, Indonesia

open access: yesEarth, Planets and Space, 2012
We use a two-dimensional tsunami sediment transport model to study the source of the 2004 earthquake. To test the model behavior, numerical experiment on sediment deposition and erosion is performed using various hypothetical parameters of tsunami ...
Aditya Riadi Gusman   +2 more
doaj   +1 more source

ASSESSMENT OF GAS-HYDROTHERMAL ACTIVITY OF THE BAIKAL RIFT IN THE LAKE AREA FROM NUMERICAL EXPERIMENT DATA

open access: yesГеодинамика и тектонофизика, 2015
The Baikal rift is characterized by high heat flow, seismic activity and large thickness of sediments through which gas and hydrothermal water are intensely released into the lake water.
V. I. Gunin
doaj   +1 more source

Towards the Optimal Design of Numerical Experiments [PDF]

open access: yesIEEE Transactions on Neural Networks, 2008
This paper addresses the problem of the optimal design of numerical experiments for the construction of nonlinear surrogate models. We describe a new method, called learner disagreement from experiment resampling (LDR), which borrows ideas from active learning and from resampling methods: the analysis of the divergence of the predictions provided by a ...
Gazut, Stéphane   +3 more
openaire   +3 more sources

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

Influence of structural parameters of the masonry on effective elastic properties and strength

open access: yesИнженерно-строительный журнал, 2014
Two phase masonry model, which contains elastic mortar and elastic bricks, is analyzed numerically in order to evaluate sensitivity of effective elastic moduli and strength properties to a deviation in the masonry structural parameters. Different methods
А.I. Grishchenko   +3 more
doaj   +1 more source

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

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