Results 61 to 70 of about 4,212,854 (223)

Structure‐forward targeting of claudins with synthetic binders

open access: yesFEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Annual report, Agricultural Experiment Station, University of Minnesota, 1893

open access: yes, 1894
1 electronic resource (PDF, xxii pages)University of Minnesota. Agricultural Experiment Station. (1894). Annual report, Agricultural Experiment Station, University of Minnesota, 1893.
University of Arizona. Agricultural Experiment Station.   +1 more
core  

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

open access: yesFEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas   +4 more
wiley   +1 more source

Winter spraying for the apple aphis (040, Agricultural Experiment Bulletin, 1904)

open access: yes, 1904
18 p., University of Idaho Agricultural Experiment Station, Bulletin No.
Aldrich, John M.
core  

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

open access: yesFEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt   +8 more
wiley   +1 more source

Soil and Water Conservation and Management Research at the Wheatland Conservation Experiment Station

open access: yes, 1953
The Oklahoma Agricultural Experiment Station periodically issues revisions to its publications. The most current edition is made available. For access to an earlier edition, if available for this title, please contact the Oklahoma State University ...
Darlow, A. E., Hawkins, Louis Edward
core  

Numerical Analysis of Impact Resistance of Prefabricated Polypropylene Fiber-Reinforced Concrete Sandwich Wall Panels

open access: yesBuildings
In order to explore new wall panel materials and structural systems suitable for prefabricated buildings, this study proposes a polypropylene fiber-reinforced concrete sandwich wall panel (PFRC sandwich wall panel) and a polypropylene fiber-reinforced ...
Yingying Shang   +3 more
doaj   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

Fertilization of Native Grass Pasture on Eroded and Brush Land at the Red Plains Conservation Experiment Station

open access: yes, 1953
The Oklahoma Agricultural Experiment Station periodically issues revisions to its publications. The most current edition is made available. For access to an earlier edition, if available for this title, please contact the Oklahoma State University ...
Darlow, A. E., Hawkins, Louis Edward
core  

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

open access: yesFEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee   +2 more
wiley   +1 more source

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