Results 61 to 70 of about 144,309 (270)

A Cre‐dependent lentiviral vector for neuron subtype‐specific expression of large proteins

open access: yesFEBS Letters, EarlyView.
We designed a versatile and modular lentivector comprising a Cre‐dependent switch and self‐cleaving 2A peptide and tested it for co‐expression of GFP and a 2.8 kb gene of interest (GOI) in mouse cortical parvalbumin (PV+) interneurons and midbrain dopamine (TH+) neurons.
Weixuan Xue   +6 more
wiley   +1 more source

Structural insights into lacto‐N‐biose I recognition by a family 32 carbohydrate‐binding module from Bifidobacterium bifidum

open access: yesFEBS Letters, EarlyView.
Bifidobacterium bifidum establishes symbiosis with infants by metabolizing lacto‐N‐biose I (LNB) from human milk oligosaccharides (HMOs). The extracellular multidomain enzyme LnbB drives this process, releasing LNB via its catalytic glycoside hydrolase family 20 (GH20) lacto‐N‐biosidase domain.
Xinzhe Zhang   +5 more
wiley   +1 more source

Driver’s influence on kinematics of articulated bus

open access: yesActa Universitatis Agriculturae et Silviculturae Mendelianae Brunensis, 2013
Driver’s influence on kinematics of articulated bus. This paper studies kinematics properties of the particle coach as function of driver’s activity. The main goals are the prediction of the trajectory, the computation of the vector of velocity of each ...
Tomáš Krumpholc, Stanislav Bartoň
doaj   +1 more source

Molecular bases of circadian magnesium rhythms across eukaryotes

open access: yesFEBS Letters, EarlyView.
Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley   +1 more source

A note on a family of quadrature formulas and some applications [PDF]

open access: yesOpuscula Mathematica, 2008
In this paper a construction of a one-parameter family of quadrature formulas is presented. This family contains the classical quadrature formulas: trapezoidal rule, midpoint rule and two-point Gauss rule.
Bogusław Bożek   +2 more
doaj  

Optimal Subinterval Selection Approach for Power System Transient Stability Simulation

open access: yesEnergies, 2015
Power system transient stability analysis requires an appropriate integration time step to avoid numerical instability as well as to reduce computational demands.
Soobae Kim, Thomas J. Overbye
doaj   +1 more source

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

open access: yesFEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang   +8 more
wiley   +1 more source

CDR-Solv: Solving the Convection-Diffusion-Reaction Equation with Algebraic Sub-Grid Scale Stabilization Using Python

open access: yesApplied Sciences
The convection-diffusion-reaction (CDR) equation is a fundamental mathematical model for simulating the transport of pollutants. It is a crucial tool for addressing global environmental challenges.
Ángel P. Villota-Cadena   +3 more
doaj   +1 more source

A Transient Stability Numerical Integration Algorithm for Variable Step Sizes Based on Virtual Input

open access: yesEnergies, 2017
In order to reduce the online calculations for power system simulations of transient stability, and dramatically improve numerical integration efficiency, a transient stability numerical integration algorithm for variable step sizes based on virtual ...
Yifan Gao   +3 more
doaj   +1 more source

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