Results 81 to 90 of about 209,471 (303)

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

FEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

FEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens, Brendan W. Chandler, Anna M. Schmoker, Jaye L. Weinert, Charlotte A. Kearns, Warren T. Yacawych, Amila Šemić, Alicia M. Ebert, Bryan A. Ballif   +8 more
wiley   +1 more source

Numerical integration of an advanced Gurson model for shear loading: Application to the blanking process [PDF]

, 2013
A new extension of the Gurson damage model has been proposed recently to predict ductile fracture under shear dominated loads. The aim of this work is to verify the ability of this approach to simulate, in an accurate way, the damage evolution in ...
GERMAIN, Guénaël, DAL SANTO, Philippe, ACHOURI, Mohamed, SAIDANE, Delphine   +3 more
core   +1 more source

CDR-Solv: Solving the Convection-Diffusion-Reaction Equation with Algebraic Sub-Grid Scale Stabilization Using Python

Applied Sciences
The convection-diffusion-reaction (CDR) equation is a fundamental mathematical model for simulating the transport of pollutants. It is a crucial tool for addressing global environmental challenges.
Ángel P. Villota-Cadena, Iván P. Sandoval-Palis, Gabriel F. Grijalva-Villegas, Erick P. Herrera-Granda   +3 more
doaj   +1 more source

Generalization of Companion of Ostrowski's Type Inequality Via Riemann-Liouville Fractional Integral and Applications in Numerical Integration, Probability Theory and Special Means [PDF]

Sahand Communications in Mathematical Analysis
We apply the Riemann-Liouville fractional integral to generalize a companion of Ostrowski's type integral inequality. The present article recaptures all the results of M. W.
Faraz Mehmood, Akhmadjon Soleev
doaj   +1 more source

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

Molecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce, Simone Bini, Marialuisa Sponziello, Giorgio Grani, Giulia Fiscon, Paola Paci, Lorenzo Farina, Rosa Falcone, Valentina Maggisano, Sebastiano Filetti, Cosimo Durante, Antonella Verrienti   +11 more
wiley   +1 more source

Geometric Integration & Kahan's Method

, 2017
The first half of this talk presents a general overview of Geometric Numerical Integration of differential equations. The second half discusses geometric integrability properties of Kahan¹s method.Non UBCUnreviewedAuthor affiliation: La Trobe ...
Quispel, Reinout
core  

Numerical Solutions for Systems of Fractional and Classical Integro-Differential Equations via Finite Integration Method Based on Shifted Chebyshev Polynomials

, 2021
In this paper, the finite integration method and the operational matrix of fractional integration are implemented based on the shifted Chebyshev polynomial.
Ampol Duangpan, Ratinan Boonklurb, Matinee Juytai   +2 more
core   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Numerical analysis of structure preserving Nyström methods for Hamiltonian systems

, 2005
Energy conservation is an essential property of conservative mechanical systems that should be carried over to the numerical solution. Betsch and Steinmann proposed recently perturbed potentials to achieve energy conservation in the time integration of N-
Pfeiffer, Andreas, Arnold, Martin
core