Results 61 to 70 of about 5,204,168 (291)

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Design of quadrature rules for Müntz and Müntz-logarithmic polynomials using monomial transformation [PDF]

open access: yes, 2009
A method for constructing the exact quadratures for Müntz and Müntz-logarithmic polynomials is presented. The algorithm does permit to anticipate the precision (machine precision) of the numerical integration of Müntz-logarithmic polynomials in terms of ...
Lombardi, Guido, Guido Lombardi
core   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

open access: yesFEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

Geometric Integration & Kahan's Method

open access: yes, 2017
The first half of this talk presents a general overview of Geometric Numerical Integration of differential equations. The second half discusses geometric integrability properties of Kahan¹s method.Non UBCUnreviewedAuthor affiliation: La Trobe ...
Quispel, Reinout
core   +1 more source

Integration as a two-way process in the EU? Assessing the Relationship between the European Integration Fund and the Common Basic Principles on Integration. CEPS Paperbacks, July 2011 [PDF]

open access: yes, 2011
This report examines the nature, the limits and potential of the principle of integration as a two-way process of mutual accommodation between migrants and the receiving societies.
Atger, Anais Faure, Carrera, Sergio
core  

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

open access: yesFEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens   +8 more
wiley   +1 more source

Numerical Integration in S-PLUS or R: A Survey [PDF]

open access: yes
This paper reviews current quadrature methods for approximate calculation of integrals within S-Plus or R. Starting with the general framework, Gaussian quadrature will be discussed first, followed by adaptive rules and Monte Carlo methods.
Diego Kuonen
core  

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

Semi-Implicit Numerical Integration of Boundary Value Problems

open access: yesMathematics
The numerical solution to boundary differential problems is a crucial task in modern applied mathematics. Usually, implicit integration methods are applied to solve this class of problems due to their high numerical stability and convergence.
Maksim Galchenko   +4 more
doaj   +1 more source

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