Results 101 to 110 of about 5,204,168 (291)

Structures of mycobacterial 3‐methylcrotonyl‐CoA carboxylase reveal carrier‐domain translocation between catalytic sites

FEBS Letters, EarlyView.
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav, Bogdan I. Florea, Sebastian Geibel   +2 more
wiley   +1 more source

Benchmarking of numerical integration methods for ODE models of biological systems. [PDF]

Sci Rep, 2021
Städter P, Schälte Y, Schmiester L, Hasenauer J, Stapor PL.   +4 more
europepmc   +1 more source

Numerical integration of celestial bodies equations with taking into account regularization and use osculating elements of major planets

Vestnik Samarskogo Gosudarstvennogo Tehničeskogo Universiteta. Seriâ: Fiziko-Matematičeskie Nauki, 2010
The regular differential equations for a problem of perturbed motion are received. The computing algorithm and the program of numerical integration of the equations of celestial motion by a method of Everhart taking into account regularization and use ...
Dmitriy A Zausaev, Leonid A Solov'ev
doaj  

Theory of the Process of Vibratory Digging of Carrot Root from the Soil

AgriEngineering
Mechanical interaction during carrot harvesting can impair root quality, motivating analysis of the lifting stage before damage assessment. Therefore, an important task is the design and research of working bodies that reduce this negative impact on root
Volodymyr Bulgakov, Simone Pascuzzi, Francesco Paciolla, Gerardo Betrò, Dmytro Polishchuk, Ivan Holovach, Jüri Olt, Yevhen Ihnatiev, Maroš Korenko, Zinoviy Ruzhylo   +9 more
doaj   +1 more source

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

FEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

Dynamical Model of Rotation and Orbital Coupling for Deimos

Remote Sensing
This paper introduces a novel dynamical model, building upon the existing dynamical model for Deimos in the current numerical ephemerides, which only encompasses the simple libration effects of Deimos.
Kai Huang, Lijun Zhang, Yongzhang Yang, Mao Ye, Yuqiang Li   +4 more
doaj   +1 more source

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

FEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge, Vivian Pogenberg, Alexander Baumgart, Bente Siebels, Hartmut Schlüter, Michael Hecht‐Bucher, Aymelt Itzen   +6 more
wiley   +1 more source

Assessing the Metrological Reliability of Static Firing Tests of Rocket Motors Through the Evaluation of Thrust and Total Impulse Measurement Uncertainty

Applied Sciences
A solid propellant rocket motor is a propulsion system used in missiles and rockets that burns a propellant, typically composed of a mixture of fuel and an oxidizer, to generate the thrust necessary to propel the vehicle.
Fernando de Paula Leite Castor, Carlos Roberto Hall Barbosa, Elcio Cruz de Oliveira   +2 more
doaj   +1 more source

Prospecting the protein design landscape

FEBS Letters, EarlyView.
This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona, Katharina T. Stonig, Jens Meiler, Clara T. Schoeder, Monica L. Fernández‐Quintero   +4 more
wiley   +1 more source

L‐aspartate oxidase provides new insights into fumarate reduction in anaerobic darkness in Synechocystis sp. PCC6803

FEBS Letters, EarlyView.
Synechocystis strains deficient in succinate dehydrogenase (SDH) secrete more succinate than the WT under dark anaerobic conditions, supporting that SDH then primarily acts as SDH, not as a fumarate reductase. L‐aspartate oxidase (Laspo) from Synechocystis is functional under anaerobic conditions, reducing fumarate to succinate.
Kateryna Kukil, Jeffrey A. Hawkes, Cecilia Blikstad, Pia Lindberg   +3 more
wiley   +1 more source