Results 81 to 90 of about 337,061 (308)

Effect of chemotherapy on passenger mutations in metastatic colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Changes in passenger mutation load and predicted immunotherapy response after chemotherapy treatment. Tumor cells rich with passenger mutations have increased sensitivity to chemotherapy. Correlation of passenger mutations with neoantigen load suggests highly mutated clones promote a more effective response to immunotherapy, and therefore, first‐line ...
Marium T. Siddiqui   +6 more
wiley   +1 more source

Numerical function generators using bilinear interpolation

open access: yes2008 International Conference on Field Programmable Logic and Applications, 2008
Two-variable numerical functions are widely used in various applications, such as computer graphics and digital signal processing. Fast and compact hardware implementations are required. This paper introduces the bilinear interpolation method to produce fast and compact numerical function generators (NFGs) for two-variable functions.
Nagayama, Shinobu   +2 more
openaire   +2 more sources

Methylation biomarkers can distinguish pleural mesothelioma from healthy pleura and other pleural pathologies

open access: yesMolecular Oncology, EarlyView.
We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck   +12 more
wiley   +1 more source

Models of Random Processes and Their Particular Application in the Optimum Linear Interpolation and Forecasting

open access: yesИзвестия высших учебных заведений России: Радиоэлектроника, 2016
Models of correlation functions of random processes are considered. Numerical methods show that efficiency of the optimum linear interpolation and forecasting is defined by higher derivative of random processes.
V. A. Golovkov
doaj  

Optimal control for a fractional tuberculosis infection model including the impact of diabetes and resistant strains

open access: yesJournal of Advanced Research, 2019
The objective of this paper is to study the optimal control problem for the fractional tuberculosis (TB) infection model including the impact of diabetes and resistant strains. The governed model consists of 14 fractional-order (FO) equations.
N.H. Sweilam   +2 more
doaj   +1 more source

Monitoring of circulating tumor DNA allows early detection of disease relapse in patients with operable breast cancer

open access: yesMolecular Oncology, EarlyView.
Monitoring circulating tumor DNA (ctDNA) in patients with operable breast cancer can reveal disease relapse earlier than radiology in a subset of patients. The failure to detect ctDNA in some patients with recurrent disease suggests that ctDNA could serve as a supplement to other monitoring approaches.
Kristin Løge Aanestad   +35 more
wiley   +1 more source

LOCAL INTERPOLATION AND APPROXIMATION IN TASKS OF HEURISTIC SYNTHESIS OF DIGITAL FILTER

open access: yesРоссийский технологический журнал, 2018
The article has an overview character with elements of generalization, but at the same time it includes information brought to the level of immediate practical implementation.
V. N. Isakov, P. I. Timoshenko
doaj   +1 more source

LINC01116, a hypoxia‐lncRNA marker of pathological lymphangiogenesis and poor prognosis in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola   +12 more
wiley   +1 more source

Bivariate High-Accuracy Hermite-Type Multiquadric Quasi-Interpolation Operators

open access: yesJournal of Mathematics
In this paper, a kind of Hermite-type multiquadric quasi-interpolation operator is constructed by combining an extended univariate multiquadric quasi-interpolation operator with a bivariate Hermite interpolation polynomial.
Ruifeng Wu
doaj   +1 more source

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