Results 61 to 70 of about 450,807 (339)

Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology

open access: yesMolecular Oncology, EarlyView.
Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts   +8 more
wiley   +1 more source

High order operator splitting methods based on an integral deferred correction framework

open access: yes, 2014
Integral deferred correction (IDC) methods have been shown to be an efficient way to achieve arbitrary high order accuracy and possess good stability properties. In this paper, we construct high order operator splitting schemes using the IDC procedure to
Christlieb, Andrew J.   +2 more
core   +1 more source

Adenosine‐to‐inosine editing of miR‐200b‐3p is associated with the progression of high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
A‐to‐I editing of miRNAs, particularly miR‐200b‐3p, contributes to HGSOC progression by enhancing cancer cell proliferation, migration and 3D growth. The edited form is linked to poorer patient survival and the identification of novel molecular targets.
Magdalena Niemira   +14 more
wiley   +1 more source

Iterative Splitting Methods for Integrodifferential Equations: Theory and Applications

open access: yesJournal of Applied Mathematics, 2014
We present novel iterative splitting methods to solve integrodifferential equations. Such integrodifferential equations are applied, for example, in scattering problems of plasma simulations.
Jürgen Geiser
doaj   +1 more source

Eigenfunctions for Liouville Operators, Classical Collision Operators, and Collision Bracket Integrals in Kinetic Theory [PDF]

open access: yes, 2010
In the kinetic theory of dense fluids the many-particle collision bracket integral is given in terms of a classical collision operator defined in the phase space.
Eu, Byung Chan
core  

Integrated genomic and proteomic profiling reveals insights into chemoradiation resistance in cervical cancer

open access: yesMolecular Oncology, EarlyView.
A comprehensive genomic and proteomic analysis of cervical cancer revealed STK11 and STX3 as a potential biomarkers of chemoradiation resistance. Our study demonstrated EGFR as a therapeutic target, paving the way for precision strategies to overcome treatment failure and the DNA repair pathway as a critical mechanism of resistance.
Janani Sambath   +13 more
wiley   +1 more source

A Novel Third Order Numerical Method for Solving Volterra Integro-Differential Equations

open access: yes, 2016
In this paper we introduce a numerical method for solving nonlinear Volterra integro-differential equations. In the first step, we apply implicit trapezium rule to discretize the integral in given equation.
Bhalekar, Sachin, Patade, Jayvant
core  

Exact Derivation of Luttinger Liquid Relation in a One-Dimensional Two-Component Quantum System with Hyperbolic Interactions

open access: yes, 1994
We present an exact calculation of the Luttinger liquid relation for the one-dimensional, two-component SC model in the interaction strength range ...
Affleck   +23 more
core   +1 more source

Inhibition of CDK9 enhances AML cell death induced by combined venetoclax and azacitidine

open access: yesMolecular Oncology, EarlyView.
The CDK9 inhibitor AZD4573 downregulates c‐MYC and MCL‐1 to induce death of cytarabine (AraC)‐resistant AML cells. This enhances VEN + AZA‐induced cell death significantly more than any combination of two of the three drugs in AraC‐resistant AML cells.
Shuangshuang Wu   +18 more
wiley   +1 more source

Numerical Solution of Integral-Algebraic Equations with Weakly Singular Kernels by k−step Methods

open access: yesИзвестия Иркутского государственного университета: Серия "Математика", 2015
In this paper we describe numerical methods for solution integral-algebraic equations wiht weakly singular kernels. Methods are based on explicit Adam’s methods, product integration methods for the integral part and on extrapolation formulas for the main
M.V. Bulatov, O.S. Budnikova
doaj  

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