Results 101 to 110 of about 922,998 (286)

Finding Optimal Zone II Settings for Distance Relays in Coordination With Directional Overcurrent Relays Using QCQP Algorithm

IEEE Access
This paper introduces a deterministic method to address coordination challenges between distance relays (DS) and directional overcurrent relays (DOR) by employing quadratic programming with quadratic constraints (QCQP).
N. Praneeth, S. T. P. Srinivas, Alivelu M. Parimi, J. Ankamma Rao, Getie Tesfaye Zelie   +4 more
doaj   +1 more source

Planning the Minimum Time and Optimal Survey Trajectory for Autonomous Underwater Vehicles in Uncertain Current

Robotics, 2015
The authors develop an approach to a “best” time path for Autonomous Underwater Vehicles conducting oceanographic measurements under uncertain current flows.
Michael A. Hurni, Kiriakos Kiriakidis
doaj   +1 more source

Tumor mutational burden as a determinant of metastatic dissemination patterns

Molecular Oncology, EarlyView.
This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal, Andrea Moreno‐Manuel, Miguel Salvadó‐Pertierra, Cristina Santos‐Vivas, Rebeca Sanz‐Pamplona   +4 more
wiley   +1 more source

NUMERICAL ANALYSIS AND OPTIMIZATION OF SUPPORTING SYSTEM FOR FOUR HORNS ASSEMBLY [PDF]

Scientific Journal of Silesian University of Technology. Series Transport, 2014
In the paper the supporting frame for four horns design for the High Intensity Neutrino Project EURONu is proposed and numerically investigated. The whole set is designed for the experimental investigations of the neutrino oscillations.
Bogdan SZYBIŃSKI
doaj  

Targeting p38α in cancer: challenges, opportunities, and emerging strategies

Molecular Oncology, EarlyView.
p38α normally regulates cellular stress responses and homeostasis and suppresses malignant transformation. In cancer, however, p38α is co‐opted to drive context‐dependent proliferation and dissemination. p38α also supports key functions in cells of the tumor microenvironment, including fibroblasts, myeloid cells, and T lymphocytes.
Angel R. Nebreda
wiley   +1 more source

Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer

Molecular Oncology, EarlyView.
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta, Yang Song, Madeleine Ndahayo, Anirudh Saxena, Theresa Guo, Dylan Z. Kelley, Jessica Gore, Andrew Hennigan, Alexa Anderson, John C. Papadimitriou, Daria A. Gaykalova   +10 more
wiley   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source

Plasmonic Nanoprism Distributions to Promote Enhanced and Uniform Energy Deposition in Passive and Active Targets

Nanomaterials
Passive and active targets, both implanted with gold nanoprisms, were designed to achieve enhanced, uniform power absorption during two-sided illumination with short laser pulses.
Dávid Vass, Emese Tóth, András Szenes, Balázs Bánhelyi, István Papp, Tamás Sándor Biró, László Pál Csernai, Norbert Kroó, Mária Csete   +8 more
doaj   +1 more source

Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin

Molecular Oncology, EarlyView.
Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon, Dong Young Kim, Yuna Kim, Uk‐Il Kim, Jae‐Sung Kim   +4 more
wiley   +1 more source

Enhancing Fire Resistance: A Thermal and Structural Optimization Approach for Fire Door Frame Using Numerical Simulation

Fire
Fire resistance is a critical aspect of passive fire protection, particularly in door systems that must maintain integrity under extreme conditions. This paper presents the thermal and structural performance of a single-leaf sandwich fire door, with the ...
Margarida Fernandes, Ana Araújo, João Silva, Nelson Rodrigues, Senhorinha Teixeira, José Carlos Teixeira   +5 more
doaj   +1 more source