Results 111 to 120 of about 245,507 (312)

Numerical Optimization to AI, and Back

open access: yesProceedings of the AAAI Conference on Artificial Intelligence, 2019
The impact of numerical optimization on modern data analysis has been quite significant. Today, these methods lie at the heart of most statistical machine learning applications in domains spanning genomics, finance and medicine. The expanding scope of these applications (and the complexity of the associated data) has continued to raise the expectations
openaire   +2 more sources

Numerical methods for topology optimization in Electromagnetics [PDF]

open access: yes
openTopology optimization (TO) is the process used to find the best material distribution of a design domain under given constraints.TO was used for the first time in the field of structural mechanics but it’s recently applied also for electromagnetics ...
BERNARDINI, CATERINA
core  

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

A Multi-Strategy Improved Seagull Optimization Algorithm for Global Optimization and Artistic Image Segmentation

open access: yesBiomimetics
Multilevel threshold image segmentation is a key task in image processing, yet it faces challenges such as low search efficiency in high-dimensional spaces, difficulty in balancing segmentation accuracy and stability, and insufficient adaptability to ...
Yangyang Jiang
doaj   +1 more source

Design optimization of permanent magnet actuators. [PDF]

open access: yes, 1992
This study describes the design optimization of permanent actuators, of both rotary and linear topologies. Parameter scanning, constrained single and multi-criterion optimization techniques are developed, with due emphasis on the efficient ...
Widdowson, G P
core  

Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma

open access: yesMolecular Oncology, EarlyView.
Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski   +10 more
wiley   +1 more source

Enhancing Fire Resistance: A Thermal and Structural Optimization Approach for Fire Door Frame Using Numerical Simulation

open access: yesFire
Fire resistance is a critical aspect of passive fire protection, particularly in door systems that must maintain integrity under extreme conditions. This paper presents the thermal and structural performance of a single-leaf sandwich fire door, with the ...
Margarida Fernandes   +5 more
doaj   +1 more source

Liquid biopsy‐based diagnostic evaluation of hypermethylated CpG sites for ovarian cancer diagnosis

open access: yesMolecular Oncology, EarlyView.
This schematic outlines the workflow from biomarker identification to duplex MethyLight assay validation for epithelial ovarian cancer diagnosis using cfDNA‐based liquid biopsy. Initial screening of hypermethylated CpG candidates (cg02957270, cg10061138 cg00480298, COL2A1) was performed in tissue using ARMS‐PCR, COBRA, qPCR and image analysis. Selected
Deepa Bisht   +3 more
wiley   +1 more source

Plasmonic Nanoprism Distributions to Promote Enhanced and Uniform Energy Deposition in Passive and Active Targets

open access: yesNanomaterials
Passive and active targets, both implanted with gold nanoprisms, were designed to achieve enhanced, uniform power absorption during two-sided illumination with short laser pulses.
Dávid Vass   +8 more
doaj   +1 more source

Numerical Optimization [PDF]

open access: yesJournal of the Operational Research Society, 2001
openaire   +1 more source

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