Results 101 to 110 of about 3,753,786 (301)

Benchmarking the HRP-2 Humanoid Robot During Locomotion

Frontiers in Robotics and AI, 2018
In this paper we report results on benchmarking a HRP-2 humanoid robot. The humanoid robots of this serie are known to be very robust. They have been successfully used by several research groups for the design of new motion generation algorithms. As such
Olivier Stasse, Kevin Giraud--Esclasse, Edouard Brousse, Maximilien Naveau, Rémi Régnier, Guillaume Avrin, Philippe Souères   +6 more
doaj   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

Mixed-Integer Linear Optimization: Primal–Dual Relations and Dual Subgradient and Cutting-Plane Methods

, 2020
This chapter presents several solution methodologies for mixed-integer linear optimization, stated as mixed-binary optimization problems, by means of Lagrangian duals, subgradient optimization, cutting-planes, and recovery of primal solutions.
Ann-Brith Strömberg, Str\uf6mberg, Ann-Brith, Torbjörn Larsson, Larsson, Torbj\uf6rn, Larsson, T., Patriksson, Michael,, Michael Patriksson, Patriksson, Michael, Larsson, Torbjörn,, Strömberg, Ann-Brith,   +9 more
core   +1 more source

Preoperative circulating tumor cells integrated with imaging analysis for prognostic evaluation in head and neck squamous cell carcinoma

Molecular Oncology, EarlyView.
Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach, Gizem Abaci, Tom Huberty, Axel Lechner, Lukas Käsmann, Jens Ricke, Sophia Stöcklein, Martin Canis, Philipp Baumeister, Marianna Alunni‐Fabbroni   +9 more
wiley   +1 more source

Quality by Design (QbD)-Based Numerical and Graphical Optimization Technique for the Development of Osmotic Pump Controlled-Release Metoclopramide HCl Tablets

Drug Design, Development and Therapy, 2020
Sadaf Farooqi,1 Rabia Ismail Yousuf,1 Muhammad Harris Shoaib,1 Kamran Ahmed,1 Sabah Ansar,2 Tazeen Husain1 1Department of Pharmaceutics, Faculty of Pharmacy and Pharmaceutical Sciences, University of Karachi, Karachi 75270, Pakistan; 2Department of ...
Farooqi S, Yousuf RI, Shoaib MH, Ahmed K, Ansar S, Husain T   +5 more
doaj  

A Gaussian Estimation of Distribution Algorithm With Random Walk Strategies and Its Application in Optimal Missile Guidance Handover for Multi-UCAV in Over-the-Horizon Air Combat

IEEE Access, 2019
To overcome the premature convergence caused by the ill-distribution of solutions in the basic Gaussian estimation of distribution algorithm (GEDA), this paper explores a novel GEDA variant with random walk strategies, namely RW-GEDA.
Xiaofei Wang, Hui Zhao, Tong Han, Zhenglei Wei, Yajun Liang, Yintong Li   +5 more
doaj   +1 more source

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

Molecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

A Conjugate Gradient-Based BPTT-Like Optimal Control Algorithm With Vehicle Dynamics Control Application [PDF]

, 2010
The paper presents a gradient-based algorithm for optimal control of nonlinear multivariable systems with control and state vectors constraints. The algorithm has a backward-in-time recurrent structure similar to the backpropagation-through-time ...
Kolmanovsky, Ilya V., Novakovic, Branko, Joško Deur, Josip Kasac, Kasac, Josip, Francis Assadian, Branko Novakovic, Deur, Josko, Assadian, Francis, Kolmanovsky, Ilya, Ilya V. Kolmanovsky   +10 more
core   +1 more source

Spatial biology in cancer epigenetics

Molecular Oncology, EarlyView.
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley   +1 more source

Numerical methods for topology optimization in Electromagnetics [PDF]

openTopology optimization (TO) is the process used to find the best material distribution of a design domain under given constraints.TO was used for the first time in the field of structural mechanics but it’s recently applied also for electromagnetics ...
BERNARDINI, CATERINA
core